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Immunogen sequence: TESLLVALP PCHLTGGNAT LMVRRANDSK VVTSSFVVPP CRGRRELVSV VDSGAGFTVT RLSAYQVTNL VPGTKFYISY LVKKGTATES SREIPMSTLP RRNMESIGLG MARTGGMVVI TVLLSVAMF (41-168 aa encoded by BC113900)
This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: UP2; UPII; Uroplakin II; Uroplakin-2
Gene Aliases: AW491716; UP2; UPII; UPK2
UniProt ID: (Human) O00526
Entrez Gene ID: (Human) 7379, (Mouse) 22269, (Rat) 689093
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