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Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MNFLRGVMGG QSAGPQHTEA ETIQKLCDRV ASSTLLDDRR NAVRALKSLS KKYRLEVGIQ AMEHLIHVLQ TDRSDSEIIG YALDTLYNII SNEEEEVEEN STRQSEDLGS QFTEIFIKQQ ENVTLLLSLL EEFDFHVRWP GVKLLTSLLK QLGPQVQQII LVSPMGVSRL MDLLADSREV IRNDGVLLLQ ALTRSNGAIQ KIVAFENAFE RLLDIISEEG NSDGGIVVED CLILLQNLLK NNNSNQNFFK EGSYIQRMKP WFEVGDENSG WSAQKVTNLH LMLQLVRVLV SPTNPPGATS SCQKAMFQCG LLQQLCTILM ATGVPADILT ETINTVSEVI RGCQVNQDYF ASVNAPSNPP RPAIVVLLMS MVNERQPFVL RCAVLYCFQC FLYKNQKGQG EIVSTLLPST IDATGNSVSA GQLLCGGLFS TDSLSNWCAA VALAHALQEN ATQKEQLLRV QLATSIGNPP VSLLQQCTNI LSQGSKIQTR VGLLMLLCTW LSNCPIAVTH FLHNSANVPF LTGQIAENLG EEEQLVQGLC ALLLGISIYF NDNSLESYMK EKLKQLIEKR IGKENFIEKL GFISKHELYS RASQKPQPNF PSPEYMIFDH EFTKLVKELE GVITKAIYKS SEEDKKEEEV KKTLEQHDNI VTHYKNMIRE QDLQLEELRQ QVSTLKCQNE QLQTAVTQQV SQIQQHKDQY NLLKIQLGKD NQHQGSYSEG AQMNGIQPEE IGRLREEIEE LKRNQELLQS QLTEKDSMIE NMKSSQTSGT NEQSSAIVSA RDSEQVAELK QELATLKSQL NSQSVEITKL QTEKQELLQK TEAFAKSVEV QGETETIIAT KTTDVEGRLS ALLQETKELK NEIKALSEER TAIKEQLDSS NSTIAILQTE KDKLELEITD SKKEQDDLLV LLADQDQKIL SLKNKLKDLG HPVEEEDELE SGDQEDEDDE SEDPGKDLDH I
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: General vesicular transport factor p115; Protein USO1 homolog; TAP; transcytosis associated protein; Transcytosis-associated protein; USO1 vesicle docking protein homolog; VDP p115; vesicle docking protein p115; Vesicle-docking protein
Gene Aliases: P115; TAP; USO1; VDP
UniProt ID: (Human) O60763
Entrez Gene ID: (Human) 8615
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