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FIGURE: 1 / 1
USP44 Antibody (PA5-110559) in WB
Western blot analysis of USP44 in extracts of various cell lines. Samples were incubated with USP44 Polyclonal antibody (Product # PA5-110559) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-110559
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 100-270 of human USP44 (NP_115523.2).
Conjugate
Form
Liquid
Concentration
1.83 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855970
Product Specific Information
Immunogen sequence: RTLSAIKSQN YHCTTRSGRF LRSMGTGDDS YFLHDGAQSL LQSEDQLYTA LWHRRRILMG KIFRTWFEQS PIGRKKQEEP FQEKIVVKRE VKKRRQELEY QVKAELESMP PRKSLRLQGL AQSTIIEIVS VQVPAQTPAS PAKDKVLSTS ENEISQKVSD SSVKRRPIVT P
Target Information
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP44 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes.[supplied by OMIM, Mar 2008].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Deubiquitinating enzyme 44; inactive deubiquitinating enzyme 44; inactive ubiquitin carboxyl-terminal hydrolase 44; inactive ubiquitin thioesterase 44; inactive ubiquitin-specific-processing protease 44; Ubiquitin carboxyl-terminal hydrolase 44; ubiquitin specific peptidase 49 pseudogene; ubiquitin specific protease 44; Ubiquitin thioesterase 44; ubiquitin thiolesterase 44; Ubiquitin-specific-processing protease 44
Gene Aliases: E430004F17Rik; USP44
UniProt ID: (Human) Q9H0E7, (Mouse) Q8C2S0
Entrez Gene ID: (Human) 84101, (Rat) 314746, (Mouse) 327799
mitotic nuclear division
protein deubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
cell division
regulation of spindle checkpoint
regulation of mitotic cell cycle spindle assembly checkpoint
negative regulation of ubiquitin protein ligase activity
biological_process
regulation of proteasomal protein catabolic process
proteolysis
ubiquitin-dependent protein catabolic process
cell cycle
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