Product References
Human Ubiquilin 2 and TDP-43 copathology drives neurodegeneration in transgenic Caenorhabditis elegans.
G3 (Bethesda, Md.)
Saxton AD,Kraemer BC
37-7700 was used in Western Blot to show that this model of UBQLN2-mediated neurodegeneration may be useful for further mechanistic investigation into the molecular cascades driving neurodegeneration in ALS and ALS-FTLD.
Sat Aug 07 00:00:00 EDT 2021
Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.
Acta neuropathologica communications
Wang S,Tatman M,Monteiro MJ
Published figure using Ubiquilin 2 monoclonal antibody (Product # 37-7700) in Immunohistochemistry
Wed Oct 07 00:00:00 EDT 2020
Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.
Acta neuropathologica communications
Wang S,Tatman M,Monteiro MJ
Published figure using Ubiquilin 2 monoclonal antibody (Product # 37-7700) in Immunohistochemistry
Wed Oct 07 00:00:00 EDT 2020
Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.
Acta neuropathologica communications
Wang S,Tatman M,Monteiro MJ
Published figure using Ubiquilin 2 monoclonal antibody (Product # 37-7700) in Immunohistochemistry
Wed Oct 07 00:00:00 EDT 2020
Signature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease.
Brain research
Safren N,Chang L,Dziki KM,Monteiro MJ
Published figure using Dsk2 monoclonal antibody (Product # 37-7700) in Western Blot
Mon Feb 09 00:00:00 EST 2015
Signature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease.
Brain research
Safren N,Chang L,Dziki KM,Monteiro MJ
Published figure using Dsk2 monoclonal antibody (Product # 37-7700) in Western Blot
Mon Feb 09 00:00:00 EST 2015
Ubiquilin-1 overexpression increases the lifespan and delays accumulation of Huntingtin aggregates in the R6/2 mouse model of Huntington's disease.
PloS one
Safren N,El Ayadi A,Chang L,Terrillion CE,Gould TD,Boehning DF,Monteiro MJ
37-7700 was used in immunohistochemistry and western blot to test if overexpression of ubiquilin-1 delays or prevents neurodegeneration in R6/2 mice
Mon Sep 29 00:00:00 EDT 2014
Nuclear proteasomes carry a constitutive posttranslational modification which derails SDS-PAGE (but not CTAB-PAGE).
Biochimica et biophysica acta
Pitcher DS,de Mattos-Shipley K,Wang Z,Tzortzis K,Goudevenou K,Flynn H,Bohn G,Rahemtulla A,Roberts I,Snijders AP,Karadimitris A,Kleijnen MF
37-7700 was used in western blot to identify the unique SDS-PAGE pattern of nuclear proteasomes.
Mon Dec 01 00:00:00 EST 2014
Studies of the role of ubiquitination in the interaction of ubiquilin with the loop and carboxyl terminal regions of presenilin-2.
Biochemistry
Ford DL,Monteiro MJ
Tue Jul 31 00:00:00 EDT 2007
Studies of the role of ubiquitination in the interaction of ubiquilin with the loop and carboxyl terminal regions of presenilin-2.
Biochemistry
Ford DL,Monteiro MJ
Tue Jul 31 00:00:00 EDT 2007
Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion.
The Journal of biological chemistry
Hiltunen M,Lu A,Thomas AV,Romano DM,Kim M,Jones PB,Xie Z,Kounnas MZ,Wagner SL,Berezovska O,Hyman BT,Tesco G,Bertram L,Tanzi RE
Fri Oct 27 00:00:00 EDT 2006
Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion.
The Journal of biological chemistry
Hiltunen M,Lu A,Thomas AV,Romano DM,Kim M,Jones PB,Xie Z,Kounnas MZ,Wagner SL,Berezovska O,Hyman BT,Tesco G,Bertram L,Tanzi RE
Fri Oct 27 00:00:00 EDT 2006