Product References
L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis.
Oncogene
Tabata S,Kojima Y,Sakamoto T,Igarashi K,Umetsu K,Ishikawa T,Hirayama A,Kajino-Sakamoto R,Sakamoto N,Yasumoto KI,Okano K,Suzuki Y,Yachida S,Aoki M,Soga T
37-7500 was used in Western Blotting to indicate that L2HG ameliorates nutritional stress by activating the mTOR-ATF4 axis and thus could be a potential therapeutic target for CRC.
Sat Apr 01 00:00:00 EDT 2023
The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma.
Haematologica
Ponnusamy K,Tzioni MM,Begum M,Robinson ME,Caputo VS,Katsarou A,Trasanidis N,Xiao X,Kostopoulos IV,Iskander D,Roberts I,Trivedi P,Auner HW,Naresh K,Chaidos A,Karadimitris A
37-7500 was used in Immunoprecipitation to show a non-canonical function of constitutive ZBP1 in human cells and expand our knowledge of the role of cellular immune sensors in cancer biology.
Tue Mar 01 00:00:00 EST 2022
Kinetoplastid-specific X2-family kinesins interact with a kinesin-like pleckstrin homology domain protein that localizes to the trypanosomal microtubule quartet.
Molecular microbiology
Benz C,Müller N,Kaltenbrunner S,Váchová H,Vancová M,Lukeš J,Varga V,Hashimi H
37-7500 was used in Immunocytochemistry-immunofluorescence to characterize in Trypanosoma brucei TbKifX2A, an orphaned X2 kinesin.
Thu Sep 01 00:00:00 EDT 2022
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Autophagy
Han T,Wang P,Wang Y,Xun W,Lei J,Wang T,Lu Z,Gan M,Zhang W,Yu B,Wang JB
37-7500 was used in Cell growth assay to discover new functions of FAIM and elucidated an important molecular mechanism for GAC in maintaining its high enzymatic activity and protein stability.
Wed Jun 01 00:00:00 EDT 2022
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.
Nature communications
Rossitto M,Déjardin S,Rands CM,Le Gras S,Migale R,Rafiee MR,Neirijnck Y,Pruvost A,Nguyen AL,Bossis G,Cammas F,Le Gallic L,Wilhelm D,Lovell-Badge R,Boizet-Bonhoure B,Nef S,Poulat F
37-7500 was used in Western Blotting to show that TRIM28 is required to prevent female-to-male sex reversal of the mouse ovary after birth.
Fri Jul 29 00:00:00 EDT 2022
Physical and functional interactome atlas of human receptor tyrosine kinases.
EMBO reports
Salokas K,Liu X,Öhman T,Chowdhury I,Gawriyski L,Keskitalo S,Varjosalo M
37-7500 was used in ELISA, Immunocytochemistry, Western Blot to apply three complementary methods to map the molecular context and substrate profiles of RTKs.
Tue Jun 07 00:00:00 EDT 2022
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy.
Science (New York, N.Y.)
Verweij MC,Hansen SG,Iyer R,John N,Malouli D,Morrow D,Scholz I,Womack J,Abdulhaqq S,Gilbride RM,Hughes CM,Ventura AB,Ford JC,Selseth AN,Oswald K,Shoemaker R,Berkemeier B,Bosche WJ,Hull M,Shao J,Sacha JB,Axthelm MK,Edlefsen PT,Lifson JD,Picker LJ,Früh K
37-7500 was used in Western Blot to show Rh67-enabled direct priming of MHC-E-restricted T cells is crucial for RhCMV/SIV vaccine efficacy.
Fri Apr 30 00:00:00 EDT 2021
SARS-CoV-2-host proteome interactions for antiviral drug discovery.
Molecular systems biology
Liu X,Huuskonen S,Laitinen T,Redchuk T,Bogacheva M,Salokas K,Pöhner I,Öhman T,Tonduru AK,Hassinen A,Gawriyski L,Keskitalo S,Vartiainen MK,Pietiäinen V,Poso A,Varjosalo M
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Immunocytochemistry
Mon Nov 01 00:00:00 EDT 2021
SARS-CoV-2-host proteome interactions for antiviral drug discovery.
Molecular systems biology
Liu X,Huuskonen S,Laitinen T,Redchuk T,Bogacheva M,Salokas K,Pöhner I,Öhman T,Tonduru AK,Hassinen A,Gawriyski L,Keskitalo S,Vartiainen MK,Pietiäinen V,Poso A,Varjosalo M
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Immunocytochemistry
Mon Nov 01 00:00:00 EDT 2021
Onset of Senescence and Steatosis in Hepatocytes as a Consequence of a Shift in the Diacylglycerol/Ceramide Balance at the Plasma Membrane.
Cells
Deevska G,Dotson PP,Mitov M,Butterfield DA,Nikolova-Karakashian M
37-7500 was used in Immunocytochemistry to show that SMS2 regulates DAG homeostasis and signaling in hepatocytes and also provide proof of principle for the concept that offset in bioactive lipids' production at the plasma membrane can drive the senescence program in association with steatosis and, seemingly, by cell-autonomous mechanisms.
Fri May 21 00:00:00 EDT 2021
Onset of Senescence and Steatosis in Hepatocytes as a Consequence of a Shift in the Diacylglycerol/Ceramide Balance at the Plasma Membrane.
Cells
Deevska G,Dotson PP,Mitov M,Butterfield DA,Nikolova-Karakashian M
37-7500 was used in Immunocytochemistry to show that SMS2 regulates DAG homeostasis and signaling in hepatocytes and also provide proof of principle for the concept that offset in bioactive lipids' production at the plasma membrane can drive the senescence program in association with steatosis and, seemingly, by cell-autonomous mechanisms.
Fri May 21 00:00:00 EDT 2021
A Yellow Fever 17D Virus Replicon-Based Vaccine Platform for Emerging Coronaviruses.
Vaccines
Oreshkova N,Myeni SK,Mishra N,Albulescu IC,Dalebout TJ,Snijder EJ,Bredenbeek PJ,Dallmeier K,Kikkert M
37-7500 was used in Western Blot to transfer mechanisms from yellow fever virus 17D vaccine to coronavirus vaccines.
Thu Dec 16 00:00:00 EST 2021
Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia.
Cell death & disease
Lai Y,Li X,Li T,Nyunoya T,Chen K,Kitsios GD,Nouraie SM,Zhang Y,McVerry BJ,Lee JS,Mallampalli RK,Zou C
37-7500 was used in Immunoprecipitation to report that a chromatin modulator protein arginine N-methyltransferase 4/coactivator-associated arginine methyltransferase 1 (PRMT4/CARM1) is elevated in human lung tissues with pneumonia and in experimental lung injury models.
Fri Sep 03 00:00:00 EDT 2021
Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia.
Cell death & disease
Lai Y,Li X,Li T,Nyunoya T,Chen K,Kitsios GD,Nouraie SM,Zhang Y,McVerry BJ,Lee JS,Mallampalli RK,Zou C
37-7500 was used in Immunoprecipitation to report that a chromatin modulator protein arginine N-methyltransferase 4/coactivator-associated arginine methyltransferase 1 (PRMT4/CARM1) is elevated in human lung tissues with pneumonia and in experimental lung injury models.
Fri Sep 03 00:00:00 EDT 2021
A visual pathway for skylight polarization processing in Drosophila.
eLife
Hardcastle BJ,Omoto JJ,Kandimalla P,Nguyen BM,Keleş MF,Boyd NK,Hartenstein V,Frye MA
37-7500 was used in Immunohistochemistry to identify computational motifs of the transformation, enabling mechanistic comparisons of multisensory integration and central processing for navigation in the brains of insects.
Tue Mar 23 00:00:00 EDT 2021
Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy.
The EMBO journal
Schutt C,Hallmann A,Hachim S,Klockner I,Valussi M,Atzberger A,Graumann J,Braun T,Boettger T
37-7500 was used in Proximity Ligation Assay (PLA), Immunocytochemistry to demonstrate that the evolutionary conserved long noncoding RNA linc-MYH plays a major role in the control of MuSC proliferation by specifically regulating composition and activity of the INO80 complex.
Mon Nov 16 00:00:00 EST 2020
Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy.
The EMBO journal
Schutt C,Hallmann A,Hachim S,Klockner I,Valussi M,Atzberger A,Graumann J,Braun T,Boettger T
37-7500 was used in Proximity Ligation Assay (PLA), Immunocytochemistry to demonstrate that the evolutionary conserved long noncoding RNA linc-MYH plays a major role in the control of MuSC proliferation by specifically regulating composition and activity of the INO80 complex.
Mon Nov 16 00:00:00 EST 2020
Intramolecular chaperone-mediated secretion of an Rhs effector toxin by a type VI secretion system.
Nature communications
Pei TT,Li H,Liang X,Wang ZH,Liu G,Wu LL,Kim H,Xie Z,Yu M,Lin S,Xu P,Dong TG
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Western Blot
Mon Apr 20 00:00:00 EDT 2020
Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes.
The Journal of biological chemistry
Zoltner M,Campagnaro GD,Taleva G,Burrell A,Cerone M,Leung KF,Achcar F,Horn D,Vaughan S,Gadelha C,Zíková A,Barrett MP,de Koning HP,Field MC
37-7500 was used in Western Blotting to conclude that suramin has multiple and complex effects on trypanosomes, but unexpectedly partially activates mitochondrial ATP-generating activity.
Fri Jun 12 00:00:00 EDT 2020
Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes.
The Journal of biological chemistry
Zoltner M,Campagnaro GD,Taleva G,Burrell A,Cerone M,Leung KF,Achcar F,Horn D,Vaughan S,Gadelha C,Zíková A,Barrett MP,de Koning HP,Field MC
37-7500 was used in Western Blotting to conclude that suramin has multiple and complex effects on trypanosomes, but unexpectedly partially activates mitochondrial ATP-generating activity.
Fri Jun 12 00:00:00 EDT 2020
TAZ Represses the Neuronal Commitment of Neural Stem Cells.
Cells
Robledinos-Antón N,Escoll M,Guan KL,Cuadrado A
37-7500 was used in Western Blotting to investigate the role of transcriptional co-factor TAZ during homeostasis of neural stem progenitor cells.
Fri Oct 02 00:00:00 EDT 2020
14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases.
PLoS pathogens
Gupta S,Ylä-Anttila P,Sandalova T,Sun R,Achour A,Masucci MG
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Western Blot
Fri Nov 01 00:00:00 EDT 2019
Identification of Genes Regulating Breast Cancer Dormancy in 3D Bone Endosteal Niche Cultures.
Molecular cancer research : MCR
McGrath J,Panzica L,Ransom R,Withers HG,Gelman IH
37-7500 was used in Western Blotting to describe several novel, potentially targetable pathways controlling breast cancer dormancy in the EN.
Mon Apr 01 00:00:00 EDT 2019
Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt.
Journal of cell science
Gleason CE,Oses-Prieto JA,Li KH,Saha B,Situ G,Burlingame AL,Pearce D
37-7500 was used in Immunoprecipitation to demonstrate that SGK1 activation occurs at a distinct subcellular compartment from that of Akt and suggests a mechanism for the selective activation of these functionally distinct mTORC2 targets through subcellular partitioning of mTORC2 activity.
Tue Apr 09 00:00:00 EDT 2019
Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism.
Biology open
Martin JB,Muccioli M,Herman K,Finnell RH,Plageman TF
37-7500 was used in Immunocytochemistry to assess a novel mechanism by which folic acid modifies epithelial cell shape during morphogenesis, shedding light onto how folic acid may prevent neural tube defects.
Tue Jan 22 00:00:00 EST 2019
Cyclin-Dependent Kinase 5 (CDK5)-Mediated Phosphorylation of Upstream Stimulatory Factor 2 (USF2) Contributes to Carcinogenesis.
Cancers
Chi TF,Horbach T,Götz C,Kietzmann T,Dimova EY
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Western Blot
Fri Apr 12 00:00:00 EDT 2019
Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A.
Autophagy
Pajares M,Rojo AI,Arias E,Díaz-Carretero A,Cuervo AM,Cuadrado A
37-7500 was used in Chromatin immunoprecipitation to determine if nuclear factor, erythroid derived 2, like 2 has an impact on chaperone-mediated autophagy modulation.
Fri Oct 11 00:00:00 EDT 2019
Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.
PLoS pathogens
Gupta S,Ylä-Anttila P,Callegari S,Tsai MH,Delecluse HJ,Masucci MG
37-7500 was used in Western Blotting to identify cellular proteins that interact with the Epstein-Barr virus encoded homologue BPLF1.
Mon Jan 01 00:00:00 EST 2018
Genetically Encoded Protein Phosphorylation in Mammalian Cells.
Cell chemical biology
Beránek V,Reinkemeier CD,Zhang MS,Liang AD,Kym G,Chin JW
37-7500 was used in Western Blotting to demonstrate the synthetic activation of a protein kinase in mammalian cells.
Thu Sep 20 00:00:00 EDT 2018
High-efficiency non-mosaic CRISPR-mediated knock-in and indel mutation in F0 Xenopus.
Development (Cambridge, England)
Aslan Y,Tadjuidje E,Zorn AM,Cha SW
37-7500 was used in Western Blotting to report a method for CRISPR-mediated genome editing in Xenopus oocytes with homology-directed repair that provides efficient non-mosaic targeted insertion of small DNA fragments in 4.4-25.7% of F0 tadpoles.
Tue Aug 01 00:00:00 EDT 2017
Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication.
mBio
Oudshoorn D,Rijs K,Limpens RWAL,Groen K,Koster AJ,Snijder EJ,Kikkert M,Bárcena M
37-7500 was used in Western Blotting to demonstrate that, for both MERS-coronavirus and SARS-coronavirus, coexpression of nonstructural proteins 3 and 4 is required and sufficient to induce double-membrane vesicles.
Tue Nov 21 00:00:00 EST 2017
Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication.
mBio
Oudshoorn D,Rijs K,Limpens RWAL,Groen K,Koster AJ,Snijder EJ,Kikkert M,Bárcena M
37-7500 was used in Western Blotting to demonstrate that, for both MERS-coronavirus and SARS-coronavirus, coexpression of nonstructural proteins 3 and 4 is required and sufficient to induce double-membrane vesicles.
Tue Nov 21 00:00:00 EST 2017
Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.
Autophagy
Pajares M,Jiménez-Moreno N,García-Yagüe ÁJ,Escoll M,de Ceballos ML,Van Leuven F,Rábano A,Yamamoto M,Rojo AI,Cuadrado A
37-7500 was used in ChIP assay to identify NFE2L2/NRF2 as a regulator of autophagy gene expression and study its role in Alzheimer disease
Sun Oct 02 00:00:00 EDT 2016
Divergent regulation of functionally distinct γ-tubulin complexes during differentiation.
The Journal of cell biology
Muroyama A,Seldin L,Lechler T
37-7500 was used in immunocytochemistry to study functionally distinct gamma-tubulin complexes and divergent regulation during differentiation
Mon Jun 20 00:00:00 EDT 2016
Evolutionary origin and functional divergence of totipotent cell homeobox genes in eutherian mammals.
BMC biology
Maeso I,Dunwell TL,Wyatt CD,Marlétaz F,Vető B,Bernal JA,Quah S,Irimia M,Holland PW
37-7500 was used in immunocytochemistry to study totipotent cell homeobox genes in eutherian mammals for functional divergence and evolutionary origin
Mon Jun 13 00:00:00 EDT 2016
Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
The Journal of biological chemistry
Fleck D,Voss M,Brankatschk B,Giudici C,Hampel H,Schwenk B,Edbauer D,Fukumori A,Steiner H,Kremmer E,Haug-Kröper M,Rossner MJ,Fluhrer R,Willem M,Haass C
377500 was used in immunoprecipitation to characterize the proteolytic cleavage of neuregulin 1 type III
Fri Jan 01 00:00:00 EST 2016
Modeling familial cancer with induced pluripotent stem cells.
Cell
Lee DF,Su J,Kim HS,Chang B,Papatsenko D,Zhao R,Yuan Y,Gingold J,Xia W,Darr H,Mirzayans R,Hung MC,Schaniel C,Lemischka IR
37-7500 was used in western blot to generate patient-derived iPSCs from a Li-Fraumeni syndrome family and assess the role of mutant p53 in the development of osteosarcoma
Thu Apr 09 00:00:00 EDT 2015
Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73.
Brain : a journal of neurology
Jinks RN,Puffenberger EG,Baple E,Harding B,Crino P,Fogo AB,Wenger O,Xin B,Koehler AE,McGlincy MH,Provencher MM,Smith JD,Tran L,Al Turki S,Chioza BA,Cross H,Harlalka GV,Hurles ME,Maroofian R,Heaps AD,Morton MC,Stempak L,Hildebrandt F,Sadowski CE,Zaritsky J,Campellone K,Morton DH,Wang H,Crosby A,Strauss KA
37-7500 was used in immunocytochemistry to describe a novel nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum.
Sat Aug 01 00:00:00 EDT 2015
Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73.
Brain : a journal of neurology
Jinks RN,Puffenberger EG,Baple E,Harding B,Crino P,Fogo AB,Wenger O,Xin B,Koehler AE,McGlincy MH,Provencher MM,Smith JD,Tran L,Al Turki S,Chioza BA,Cross H,Harlalka GV,Hurles ME,Maroofian R,Heaps AD,Morton MC,Stempak L,Hildebrandt F,Sadowski CE,Zaritsky J,Campellone K,Morton DH,Wang H,Crosby A,Strauss KA
37-7500 was used in immunocytochemistry to describe a novel nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum.
Sat Aug 01 00:00:00 EDT 2015
Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
eLife
Chojnowski A,Ong PF,Wong ES,Lim JS,Mutalif RA,Navasankari R,Dutta B,Yang H,Liow YY,Sze SK,Boudier T,Wright GD,Colman A,Burke B,Stewart CL,Dreesen O
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Western Blot
Thu Aug 27 00:00:00 EDT 2015
Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
eLife
Chojnowski A,Ong PF,Wong ES,Lim JS,Mutalif RA,Navasankari R,Dutta B,Yang H,Liow YY,Sze SK,Boudier T,Wright GD,Colman A,Burke B,Stewart CL,Dreesen O
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Western Blot
Thu Aug 27 00:00:00 EDT 2015
Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
eLife
Chojnowski A,Ong PF,Wong ES,Lim JS,Mutalif RA,Navasankari R,Dutta B,Yang H,Liow YY,Sze SK,Boudier T,Wright GD,Colman A,Burke B,Stewart CL,Dreesen O
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Western Blot
Thu Aug 27 00:00:00 EDT 2015
Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
eLife
Chojnowski A,Ong PF,Wong ES,Lim JS,Mutalif RA,Navasankari R,Dutta B,Yang H,Liow YY,Sze SK,Boudier T,Wright GD,Colman A,Burke B,Stewart CL,Dreesen O
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Western Blot
Thu Aug 27 00:00:00 EDT 2015
Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor.
Cancer cell
Lu G,Zhang Q,Huang Y,Song J,Tomaino R,Ehrenberger T,Lim E,Liu W,Bronson RT,Bowden M,Brock J,Krop IE,Dillon DA,Gygi SP,Mills GB,Richardson AL,Signoretti S,Yaffe MB,Kaelin WG
37-7500 was used in western blot to study how phosphorylation alters COP1-binding sites of oncoproteins.
Mon Aug 11 00:00:00 EDT 2014
Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.
Human molecular genetics
Lyon AN,Pineda RH,Hao le T,Kudryashova E,Kudryashov DS,Beattie CE
Tue Apr 15 00:00:00 EDT 2014
Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression.
The Journal of biological chemistry
Bailey-Elkin BA,Knaap RC,Johnson GG,Dalebout TJ,Ninaber DK,van Kasteren PB,Bredenbeek PJ,Snijder EJ,Kikkert M,Mark BL
37-7500 was used in western blot to investigate the role MERS-CoV protease in the host innate immune suppression
Fri Dec 12 00:00:00 EST 2014
Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9.
Nature communications
Shi M,Cho H,Inn KS,Yang A,Zhao Z,Liang Q,Versteeg GA,Amini-Bavil-Olyaee S,Wong LY,Zlokovic BV,Park HS,García-Sastre A,Jung JU
37-7500 was used in immunoprecipitation and western blot to analyze NF-kappaB activity and its negative regulation by brain-specific TRIpartite Motif protein 9
Fri Sep 05 00:00:00 EDT 2014
Lamin B1 fluctuations have differential effects on cellular proliferation and senescence.
The Journal of cell biology
Dreesen O,Chojnowski A,Ong PF,Zhao TY,Common JE,Lunny D,Lane EB,Lee SJ,Vardy LA,Stewart CL,Colman A
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Western Blot
Mon Mar 04 00:00:00 EST 2013
Characterization of FUS mutations in amyotrophic lateral sclerosis using RNA-Seq.
PloS one
van Blitterswijk M,Wang ET,Friedman BA,Keagle PJ,Lowe P,Leclerc AL,van den Berg LH,Housman DE,Veldink JH,Landers JE
37-7500 was used in western blot to investigate the role of fused in sarcoma/translated in liposarcoma (FUS) in amyotrophic lateral sclerosis.
Tue Oct 22 00:00:00 EDT 2013
Phosphorylation of CalDAG-GEFI by protein kinase A prevents Rap1b activation.
Journal of thrombosis and haemostasis : JTH
Subramanian H,Zahedi RP,Sickmann A,Walter U,Gambaryan S
37-7500 was used in immunoprecipitation to elucidate Rap1b regulation by PKA and PKG.
Thu Aug 01 00:00:00 EDT 2013
DLC1 interaction with α-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activity.
Molecular and cellular biology
Tripathi V,Popescu NC,Zimonjic DB
Fri Jun 01 00:00:00 EDT 2012
Primary hyperoxaluria type 1 and brachydactyly mental retardation syndrome caused by a novel mutation in AGXT and a terminal deletion of chromosome 2.
American journal of medical genetics. Part A
Tammachote R,Kingsuwannapong N,Tongkobpetch S,Srichomthong C,Yeetong P,Kingwatanakul P,Monico CG,Suphapeetiporn K,Shotelersuk V
37-7500 was used in immunocytochemistry to report on a girl who had phenotypes of both primary hyperoxaluria type and brachydactyly mental retardation syndrome.
Sat Sep 01 00:00:00 EDT 2012
Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis.
PLoS genetics
Winter SF,Lukes L,Walker RC,Welch DR,Hunter KW
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Immunoprecipitation
Tue May 01 00:00:00 EDT 2012
Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis.
PLoS genetics
Winter SF,Lukes L,Walker RC,Welch DR,Hunter KW
Published figure using V5 Tag monoclonal antibody (Product # 37-7500) in Immunoprecipitation
Tue May 01 00:00:00 EDT 2012
Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs.
The Journal of biological chemistry
Van Etten J,Schagat TL,Hrit J,Weidmann CA,Brumbaugh J,Coon JJ,Goldstrohm AC
37-7500 was used in western blot to study the role of deacetylase recruitment in the mechanism by which human Pumilio proteins repress mRNA translation.
Fri Oct 19 00:00:00 EDT 2012
Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4.
Cancer research
Powers MA,Fay MM,Factor RE,Welm AL,Ullman KS
37-7500 was used in western blot to explore the significance of PDCD4 in breast cancer.
Mon Aug 15 00:00:00 EDT 2011
Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction.
Experimental physiology
Bento CF,Fernandes R,Matafome P,Sena C,Seiça R,Pereira P
37-7500 was used in western blot to study how methylglyoxal affects retinal endothelial cells
Wed Sep 01 00:00:00 EDT 2010
The chaperone-dependent ubiquitin ligase CHIP targets HIF-1α for degradation in the presence of methylglyoxal.
PloS one
Bento CF,Fernandes R,Ramalho J,Marques C,Shang F,Taylor A,Pereira P
37-7500 was used in Western Blotting to suggest that accumulation of MGO is likely to be the link between high glucose and the loss of cell response to hypoxia in diabetes.
Mon Nov 29 00:00:00 EST 2010
Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.
Cancer research
Liu D,Hou P,Liu Z,Wu G,Xing M
37-7500 was used in western blot to study the genotype-dependent therapeutic potential of targeting the phosphoinositide 3-kinase/Akt pathway for thyroid cancer
Tue Sep 15 00:00:00 EDT 2009
The COOH-terminal domain of the JIL-1 histone H3S10 kinase interacts with histone H3 and is required for correct targeting to chromatin.
The Journal of biological chemistry
Bao X,Cai W,Deng H,Zhang W,Krencik R,Girton J,Johansen J,Johansen KM
Fri Nov 21 00:00:00 EST 2008
The COOH-terminal domain of the JIL-1 histone H3S10 kinase interacts with histone H3 and is required for correct targeting to chromatin.
The Journal of biological chemistry
Bao X,Cai W,Deng H,Zhang W,Krencik R,Girton J,Johansen J,Johansen KM
Fri Nov 21 00:00:00 EST 2008
The c-myc DNA-unwinding element-binding protein modulates the assembly of DNA replication complexes in vitro.
The Journal of biological chemistry
Casper JM,Kemp MG,Ghosh M,Randall GM,Vaillant A,Leffak M
Fri Apr 01 00:00:00 EST 2005
