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VDAC2/VDAC3 Antibody (PA1-41205) in WB
Western blot analysis of VDAC2/VDAC3 in human brain cell lysate in the A) absence and B) presence of immunizing peptide using this antibody. Samples were incubated in VDAC2/VDAC3 polyclonal antibody (Product # PA1-41205). The approximately 55 kD band is not blocked by the immunizing peptide and is believed to result from non-specific cross-reaction.
Product Details
PA1-41205
Product Specifications
Species Reactivity
Bovine,
Dog,
Cat,
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues K(120) K S G K I K S S Y K R E(132) of human VDaC2.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2212344
Product Specific Information
Suggested positive control: human brain cell lysate, antigen standard for VDAC2 (transient overexpression lysate), human brain protein.
Target Information
The Voltage-Dependant Anion Channel (VDAC) of the outer mitochondrial membrane, a small abundant protein found in all eukaryotic kingdoms, forms a voltage-gated pore when incorporated into planar lipid bilayers. VDAC is also the site of binding of the metabolic enzymes hexokinase and glycerol kinase to the mitochondrion in what may be a significant metabolic regulatory interaction. VDAC3 is involved specifically in translocation of adenine nucleotides through the outer membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ23841; hVDAC-2; hVDAC-3; Outer mitochondrial membrane protein porin 2; Outer mitochondrial membrane protein porin 3; RP11-375G3.1; VDAC-2; VDAC-3; voltage-dependent anion channel 1 pseudogene 5; voltage-dependent anion channel 2; voltage-dependent anion channel 3; voltage-dependent anion channel 5, pseudogene; Voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 3
Gene Aliases: HD-VDAC3; POR; VDAC-3; VDAC1P5; VDAC2; VDAC3; VDAC5P
UniProt ID: (Bovine) P68002, (Human) P45880, (Bovine) Q9MZ13, (Human) Q9Y277
Entrez Gene ID: (Bovine) 282120, (Dog) 479255, (Human) 7417, (Bovine) 282716, (Human) 7419, (Dog) 606963
binding of sperm to zona pellucida
inorganic anion transport
anion transmembrane transport
anion transport
negative regulation of protein polymerization
transmembrane transport
regulation of anion transmembrane transport
negative regulation of intrinsic apoptotic signaling pathway
regulation of cilium assembly
adenine transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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