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Product Details
H00007424-B02P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
VEGFC (ABM85407.1, 1 a.a. approximately 419 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MHLLGFFSVA CSLLAAALLP GPREAPAAAA AFESGLDLSD AEPDAGEATA YASKDLEEQL RSVSSVDELM TVLYPEYWKM YKCQLRKGGW QHNREQANLN SRTEETIKFA AAHYNTEILK SIDNEWRKTQ CMPREVCIDV GKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY LSKTLFEITV PLSQGPKPVT ISFANHTSCR CMSKLDVYRQ VHSIIRRSLP ATLPQCQAAN KTCPTNYMWN NHICRCLAQE DFMFSSDAGD DSTDGFHDIC GPNKELDEET CQCVCRAGLR PASCGPHKEL DRNSCQCVCK NKLFPSQCGA NREFDENTCQ CVCKRTCPRN QPLNPGKCAC ECTESPQKCL LKGKKFHHQT CSCYRRPCTN RQKACEPGFS YSEEVCRCVP SYWKRPQMS
Target Information
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Flt4 ligand; FLT4 ligand DHM; Flt4-L; Vascular endothelial growth factor C; Vascular endothelial growth factor-related protein; VEGF-C; VEGF3; VRP
Gene Aliases: Flt4-L; LMPH1D; VEGFC; VRP
UniProt ID: (Human) P49767
Entrez Gene ID: (Human) 7424
angiogenesis
positive regulation of cell-matrix adhesion
positive regulation of neuroblast proliferation
platelet degranulation
substrate-dependent cell migration
signal transduction
positive regulation of cell proliferation
negative regulation of cell proliferation
organ morphogenesis
morphogenesis of embryonic epithelium
regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein autophosphorylation
response to drug
positive regulation of blood vessel endothelial cell migration
positive regulation of angiogenesis
negative regulation of blood pressure
vascular endothelial growth factor receptor signaling pathway
positive regulation of epithelial cell proliferation
positive regulation of protein secretion
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
induction of positive chemotaxis
positive regulation of cell division
positive regulation of mast cell chemotaxis
positive regulation of lymphangiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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