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Product Details
PA5-106916
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human VEGFC(Accession P49767), corresponding to amino acid residues L171-V221.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854580
Product Specific Information
Antibody detects endogenous levels of total VEGFC.
Target Information
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Flt4 ligand; FLT4 ligand DHM; Flt4-L; Vascular endothelial growth factor C; vascular endothelial growth factor C isoform 129; vascular endothelial growth factor C isoform 184; Vascular endothelial growth factor-related protein; VEGF-C; VEGF3; VRP
Gene Aliases: AW228853; Flt4-L; LMPH1D; VEGF-C; VEGFC; VRP
UniProt ID: (Human) P49767, (Rat) O35757, (Mouse) P97953
Entrez Gene ID: (Human) 7424, (Rat) 114111, (Mouse) 22341
angiogenesis
positive regulation of cell-matrix adhesion
positive regulation of neuroblast proliferation
platelet degranulation
substrate-dependent cell migration
signal transduction
positive regulation of cell proliferation
negative regulation of cell proliferation
organ morphogenesis
morphogenesis of embryonic epithelium
regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein autophosphorylation
response to drug
positive regulation of blood vessel endothelial cell migration
positive regulation of angiogenesis
negative regulation of blood pressure
vascular endothelial growth factor receptor signaling pathway
positive regulation of epithelial cell proliferation
positive regulation of protein secretion
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
induction of positive chemotaxis
positive regulation of cell division
positive regulation of mast cell chemotaxis
positive regulation of lymphangiogenesis
regulation of angiogenesis
multicellular organism development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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