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VEGFC Antibody (MA5-11119) in WB
Western blot analysis of VEGFC in various lysates. Samples were incubated with VEGFC monoclonal antibody (Product # MA5-11119) using a dilution of 1:2,000 followed by Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: human ovary lysate; Lane 2: human testis lysate; Lane 3: mouse heart lysate. Predicted band size: 47 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
MA5-11119
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
30AT1174.77
Immunogen
KLH conjugated synthetic peptides selected from the N-terminal, central, and C-terminal regions of human VEGF3
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2256994
Target Information
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Flt4 ligand; FLT4 ligand DHM; Flt4-L; Vascular endothelial growth factor C; vascular endothelial growth factor C isoform 129; vascular endothelial growth factor C isoform 184; Vascular endothelial growth factor-related protein; VEGF-C; VEGF3; VRP
Gene Aliases: AW228853; Flt4-L; LMPH1D; VEGF-C; VEGFC; VRP
UniProt ID: (Human) P49767, (Mouse) P97953
Entrez Gene ID: (Human) 7424, (Mouse) 22341
angiogenesis
positive regulation of cell-matrix adhesion
positive regulation of neuroblast proliferation
platelet degranulation
substrate-dependent cell migration
signal transduction
positive regulation of cell proliferation
negative regulation of cell proliferation
organ morphogenesis
morphogenesis of embryonic epithelium
regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein autophosphorylation
response to drug
positive regulation of blood vessel endothelial cell migration
positive regulation of angiogenesis
negative regulation of blood pressure
vascular endothelial growth factor receptor signaling pathway
positive regulation of epithelial cell proliferation
positive regulation of protein secretion
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
induction of positive chemotaxis
positive regulation of cell division
positive regulation of mast cell chemotaxis
positive regulation of lymphangiogenesis
multicellular organism development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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