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VEGFD Antibody (PA5-88271) in WB
Western blot analysis of VEGFD in extracts of NCI-H460 cells. Samples were incubated with VEGFD Polyclonal antibody (Product # PA5-88271) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product Details
PA5-88271
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human VEGF-D (NP_0044601)
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804791
Product Specific Information
Immunogen sequence: QGSSNEHGPV KRSSQSTLER SEQQIRAASS LEELLRITHS EDWKLWRCRL RLKSFTSMDS RSASHRSTRF AATFYDIETL KVIDEEWQRT QCSPRETCVE VASELGKSTN TFFKPPCVNV FRCGGCCNEE SLICMNTSTS YISKQLFEIS VPLTSVPELV PVKVANHTGC KCLPTAPRHP YSIIRRSIQI PEEDRCSHSK K; Positive Samples: NCI-H460
Target Information
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-fos induced growth factor (vascular endothelial growth factor D); c-Fos-induced growth factor; FIGF; Vascular endothelial growth factor D; VEGF-D; VEGF4
Gene Aliases: FIGF; VEGF-D; VEGFD
UniProt ID: (Human) O43915
Entrez Gene ID: (Human) 2277
angiogenesis
response to hypoxia
platelet degranulation
cell proliferation
positive regulation of cell proliferation
regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of interleukin-6 production
vascular endothelial growth factor receptor signaling pathway
positive chemotaxis
induction of positive chemotaxis
positive regulation of cell division
positive regulation of mast cell chemotaxis
response to interleukin-1
dopaminergic neuron differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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