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VEGFD Antibody (MA5-37878) in WB
Western blot analysis of VEGFD in extracts of various cell lines. Samples were incubated with VEGFD Monoclonal antibody (Product # MA5-37878) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
MA5-37878
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC2402
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human VEGF-D (O43915)
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897798
Product Specific Information
Positive Samples: HT-29, A-549, NCI-H460, H9C2, Mouse lung, Mouse heart, Rat heart
Immunogen sequence: YSIIRRSIQI PEEDRCSHSK KLCPIDMLWD SNKCKCVLQE ENPLAGTEDH SHLQEPALCG PHMMFDEDRC ECVCKTPCPK DLIQHPKNCS CFECKESLET C
Target Information
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-fos induced growth factor (vascular endothelial growth factor D); c-Fos-induced growth factor; FIGF; Vascular endothelial growth factor D; VEGF-D; VEGF4
Gene Aliases: AI325264; FIGF; VEGF-D; VEGFD
UniProt ID: (Human) O43915, (Mouse) P97946, (Rat) O35251
Entrez Gene ID: (Human) 2277, (Mouse) 14205, (Rat) 360457
platelet-derived growth factor receptor binding
vascular endothelial growth factor receptor binding
protein binding
growth factor activity
chemoattractant activity
protein homodimerization activity
vascular endothelial growth factor receptor 3 binding
vascular endothelial growth factor receptor 2 binding
growth factor
angiogenesis
response to hypoxia
platelet degranulation
cell proliferation
positive regulation of cell proliferation
regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of interleukin-6 production
vascular endothelial growth factor receptor signaling pathway
positive chemotaxis
induction of positive chemotaxis
positive regulation of cell division
positive regulation of mast cell chemotaxis
response to interleukin-1
dopaminergic neuron differentiation
cell differentiation
positive regulation of angiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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