Proteintech

VPS33B Polyclonal Antibody

VPS33B Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 17

VPS33B Antibody (12195-1-AP) in ICC/IF

Immunofluorescent analysis of MCF-7 cells, using VPS33B antibody 12195-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

VPS33B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

12195-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:10-1:100

View 5 publications 5 publications

Immunoprecipitation (IP)

Assay-dependent

View 2 publications 2 publications

ChIP assay (ChIP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

VPS33B Fusion Protein Ag2833 (318-617 aa encoded by BC016445)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MDIKQMKNF VSQELKGLKQ EHRLLSLHIG ACESIMKKKT KQDFQELIKT EHALLEGFNI RESTSYIEEH IDRQVSPIES LRLMCLLSIT ENGLIPKDYR SLKTQYLQSY GPEHLLTFSN LRRAGLLTEQ APGDTLTAVE SKVSKLVTDK AAGKITDAFS SLAKRSNFRA ISKKLNLIPR VDGEYDLKVP RDMAYVFSGA YVPLSCRIIE QVLERRSWQG LDEVVRLLNC SDFAFTDMTK EDKASSESLR LILVVFLGGC TFSEISALRF LGREKGYRFI FLTTAVTNSA RLMEAMSEVK A (318-617 aa encoded by BC016445)

Target Information

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.

Cancer science

Ning Y,Zeng Z,Deng Y,Feng W,Huang L,Liu H,Lin J,Zhang C,Fan Y,Liu L

Sat May 01 00:00:00 EDT 2021

VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.

Cancer science

Ning Y,Zeng Z,Deng Y,Feng W,Huang L,Liu H,Lin J,Zhang C,Fan Y,Liu L

Sat May 01 00:00:00 EDT 2021

VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.

Cancer science

Ning Y,Zeng Z,Deng Y,Feng W,Huang L,Liu H,Lin J,Zhang C,Fan Y,Liu L

Sat May 01 00:00:00 EDT 2021

VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.

Cancer science

Ning Y,Zeng Z,Deng Y,Feng W,Huang L,Liu H,Lin J,Zhang C,Fan Y,Liu L

Sat May 01 00:00:00 EDT 2021

Circadian control of the secretory pathway maintains collagen homeostasis.

Nature cell biology

Chang J,Garva R,Pickard A,Yeung CC,Mallikarjun V,Swift J,Holmes DF,Calverley B,Lu Y,Adamson A,Raymond-Hayling H,Jensen O,Shearer T,Meng QJ,Kadler KE

Wed Jan 01 00:00:00 EST 2020

Eyes shut homolog (EYS) interacts with matriglycan of O-mannosyl glycans whose deficiency results in EYS mislocalization and degeneration of photoreceptors.

Scientific reports

Liu Y,Yu M,Shang X,Nguyen MHH,Balakrishnan S,Sager R,Hu H

Fri May 08 00:00:00 EDT 2020

VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.

International journal of cancer

Chen Y,Liu Z,Wang H,Tang Z,Liu Y,Liang Z,Deng X,Zhao M,Fu Q,Li L,Cai H,Xie W,Fang W

Wed Jan 15 00:00:00 EST 2020

VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.

International journal of cancer

Chen Y,Liu Z,Wang H,Tang Z,Liu Y,Liang Z,Deng X,Zhao M,Fu Q,Li L,Cai H,Xie W,Fang W

Wed Jan 15 00:00:00 EST 2020

Decreased expression of VPS33B correlates with disease progression and unfavorable prognosis in renal cell carcinoma.

International journal of clinical and experimental pathology

Zhang L,Xiao Y,Zhong X,Zeng Q,Hu W

Fri Jan 17 00:00:00 EST 2020

Cellular interactome analysis of vaccinia virus K7 protein identifies three transport machineries as binding partners for K7.

Virus genes

Li Y,Zhang L,Ke Y

Fri Dec 01 00:00:00 EST 2017

Cellular interactome analysis of vaccinia virus K7 protein identifies three transport machineries as binding partners for K7.

Virus genes

Li Y,Zhang L,Ke Y

Fri Dec 01 00:00:00 EST 2017

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.

The Journal of biological chemistry

van der Kant R,Jonker CT,Wijdeven RH,Bakker J,Janssen L,Klumperman J,Neefjes J

Fri Dec 18 00:00:00 EST 2015

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.

The Journal of biological chemistry

van der Kant R,Jonker CT,Wijdeven RH,Bakker J,Janssen L,Klumperman J,Neefjes J

Fri Dec 18 00:00:00 EST 2015

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.

The Journal of biological chemistry

van der Kant R,Jonker CT,Wijdeven RH,Bakker J,Janssen L,Klumperman J,Neefjes J

Fri Dec 18 00:00:00 EST 2015

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.

The Journal of biological chemistry

van der Kant R,Jonker CT,Wijdeven RH,Bakker J,Janssen L,Klumperman J,Neefjes J

Fri Dec 18 00:00:00 EST 2015

Glomerular involvement in the arthrogryposis, renal dysfunction and cholestasis syndrome.

Clinical kidney journal

Holme A,Hurcombe JA,Straatman-Iwanowska A,Inward CI,Gissen P,Coward RJ

Mon Apr 01 00:00:00 EDT 2013

Glomerular involvement in the arthrogryposis, renal dysfunction and cholestasis syndrome.

Clinical kidney journal

Holme A,Hurcombe JA,Straatman-Iwanowska A,Inward CI,Gissen P,Coward RJ

Mon Apr 01 00:00:00 EDT 2013

Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.

Journal of cell science

van der Kant R,Fish A,Janssen L,Janssen H,Krom S,Ho N,Brummelkamp T,Carette J,Rocha N,Neefjes J

Thu Aug 01 00:00:00 EDT 2013

Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.

Journal of cell science

van der Kant R,Fish A,Janssen L,Janssen H,Krom S,Ho N,Brummelkamp T,Carette J,Rocha N,Neefjes J

Thu Aug 01 00:00:00 EDT 2013

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification.

Proceedings of the National Academy of Sciences of the United States of America

Wong D,Bach H,Sun J,Hmama Z,Av-Gay Y

Tue Nov 29 00:00:00 EST 2011

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification.

Proceedings of the National Academy of Sciences of the United States of America

Wong D,Bach H,Sun J,Hmama Z,Av-Gay Y

Tue Nov 29 00:00:00 EST 2011

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification.

Proceedings of the National Academy of Sciences of the United States of America

Wong D,Bach H,Sun J,Hmama Z,Av-Gay Y

Tue Nov 29 00:00:00 EST 2011

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification.

Proceedings of the National Academy of Sciences of the United States of America

Wong D,Bach H,Sun J,Hmama Z,Av-Gay Y

Tue Nov 29 00:00:00 EST 2011

Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

Nature genetics

Cullinane AR,Straatman-Iwanowska A,Zaucker A,Wakabayashi Y,Bruce CK,Luo G,Rahman F,Gürakan F,Utine E,Ozkan TB,Denecke J,Vukovic J,Di Rocco M,Mandel H,Cangul H,Matthews RP,Thomas SG,Rappoport JZ,Arias IM,Wolburg H,Knisely AS,Kelly DA,Müller F,Maher ER,Gissen P

Thu Apr 01 00:00:00 EDT 2010

Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

Nature genetics

Thu Apr 01 00:00:00 EDT 2010

Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

Nature genetics

Thu Apr 01 00:00:00 EDT 2010

Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

Nature genetics

Thu Apr 01 00:00:00 EDT 2010

Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

Nature genetics

Thu Apr 01 00:00:00 EDT 2010

Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.

Nature genetics

Thu Apr 01 00:00:00 EDT 2010

Bioinformatics

Protein Aliases: FLJ14848; hVPS33B; r-vps33b; vacuolar protein sorting 33 homolog B; vacuolar protein sorting 33-like protein B; vacuolar protein sorting 33B; vacuolar protein sorting homolog r-vps33b; Vacuolar protein sorting-associated protein 33B

View more View less

Gene Aliases: VPS33B

View more View less

UniProt ID: (Human) Q9H267, (Mouse) P59016, (Rat) Q63616

View more View less

Entrez Gene ID: (Human) 26276, (Mouse) 233405, (Rat) 64060

View more View less

Function(s)

protein binding syntaxin binding syntaxin-3 binding membrane trafficking regulatory protein

Process(es)

vesicle docking involved in exocytosis endosome organization endosome to lysosome transport protein transport vesicle-mediated transport melanosome localization lysosome localization megakaryocyte development membrane fusion platelet alpha granule organization regulation of platelet aggregation autophagosome maturation transport biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

VPS33B Polyclonal Antibody

VPS33B Antibody (12195-1-AP) in ICC/IF

Product Details

12195-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!