Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MISFCPDCG KSIQAAFKFC PYCGNSLPVE EHVGSQTFVN PHVSSFQGSK RGLNSSFETS PKKVKWSSTV TSPRLSLFSD GDSSESEDTL SSSERSKGSG SRPPTPKSSP QKTRKSPQVT RGSPQKTSCS PQKTRQSPQT LKRSRVTTSL EALPTGTVLT DKSGRQWKLK SFQTRDNQGI LYEAAPTSTL TCDSGPQKQK FSLKLDAKDG RLFNEQNFFQ RAAKPLQVNK WKKLYSTPLL AIPTCMGFGV HQDKYRFLVL PSLGRSLQSA LDVSPKHVLS ERSVLQVACR LLDALEFLHE NE (1-301 aa encoded by BC023556)
This gene encodes a member of the vaccinia-related kinase family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Serine/threonine-protein kinase VRK3; serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3
Gene Aliases: VRK3
UniProt ID: (Human) Q502Y2
Entrez Gene ID: (Human) 51231
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support