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T cell activation by APCs is positively and negatively regulated by members of the B7 family. VSIG4 is a strong negative regulator of murine and human T cell proliferation and IL-2 production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: complement receptor of the immunoglobulin superfamily; Ig superfamily protein; Protein Z39Ig; V-set and immunoglobulin domain-containing protein 4
Gene Aliases: A530061A11; BC025105; CRIg; UNQ317/PRO362; VSIG4; Z39IG
UniProt ID: (Human) Q9Y279
Entrez Gene ID: (Human) 11326, (Rat) 312102, (Mouse) 278180
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