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Immunogen sequence: MALHSMRKA RERWSFIRAL HKGSAAAPAL QKDSKKRVFS GIQPTGILHL SNYLGAIESW VRLQDEYDSV LYSIVDLHSI TVPQDPAVLR QSILDMTAVL LACGINPEKS ILFQQSQVSE HTQLSWILSC MVRLPRLQHL HQWKAKTTKQ KHDGTVGLLT YPVLQAADIL LYKSTHVPVG EDQVQHMELV QDLAQGFNKK YGEFFPVPES ILTSMKKVKS LRDPSAKMSK SDPDKLATVR ITDSPEEIVQ KFRKAVTDFT SEVTYDPAGR AGVSNIVAVH AAVTGLSVEE VVRRSAGMNT ARYKLAVADA VIEKFAPIKR EIEKLKLDKD HLEKVLQIGS AKAKELAYTV CQEVKKLVGF L (1-360 aa encoded by BC044575)
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described.
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Protein Aliases: (Mt)TrpRS; TrpRS; tryptophan tRNA ligase 2, mitochondrial; Tryptophan--tRNA ligase, mitochondrial; Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase, mitochondrial
Gene Aliases: 5730427B17Rik; 9430020O07Rik; AI413375; TrpRS; WARS2
UniProt ID: (Human) Q9UGM6, (Mouse) Q9CYK1
Entrez Gene ID: (Human) 10352, (Rat) 690654, (Mouse) 70560
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