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Immunogen sequence: APLNVSMSPT GDFLATSHVD HLGIYLWSNI SLYSVVSLRP LPADYVPSIV MLPGTCQTQD VEVSEETVEP SDELIEYDSP EQLNEQLVTL S
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: T-cell activation WD repeat protein; T-cell activation WD repeat-containing protein; TA-WDRP; WD repeat-containing protein 36
Gene Aliases: GLC1G; TA-WDRP; TAWDRP; UTP21; WDR36
UniProt ID: (Human) Q8NI36
Entrez Gene ID: (Human) 134430
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