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Product Details
PA5-21012
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 21 amino acid peptide near the center of human WDR92.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11153216
Product Specific Information
A suggested positive control is human kidney tissue lysate.
PA5-21012 can be used with blocking peptide PEP-1126.
Target Information
WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR92, also known as monad, contains two WD40 repeats is widely expressed in human tissues, especially testis. Overexpression of this protein or its binding partner RNA polymerase II-associated protein 3 (RPAP3) potentiated apoptosis and caspase-3 activation induced by TNF-a and cycloheximide, suggesting that WDR92, together with RPAP3, may function as a novel modulator of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dynein axonemal assembly factor 10; monad; testicular secretory protein Li 67; WD repeat-containing protein 92; WD repeat-containing protein Monad
Gene Aliases: AI553587; DNAAF10; HZGJ; WDR92
UniProt ID: (Human) Q96MX6, (Mouse) Q8BGF3
Entrez Gene ID: (Human) 116143, (Mouse) 103784
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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