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Invitrogen
WIPI1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-52443
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human WIPI1. Recombinant protein control fragment (Product #RP-89638).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2649653
Product Specific Information
Immunogen sequence: HQDRAFATAR LNFSGQRNIC TLSTIQKLPR LLVASSSGHL YMYNLDPQDG GECVLIKTHS LLGSGTTEEN KENDLRPSLP QSYAATVARP SASSASTVPG YSEDGGALRG EVIPEHEFAT GPVCLDDENE FPPIILCRG
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
Target Information
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Atg18 protein homolog; WD repeat domain phosphoinositide-interacting protein 1; WD40 repeat protein interacting with phosphoinositides of 49 kDa; WD40 repeat protein Interacting with phosphoInositides of 49kDa; WIPI 49 kDa; WIPI-1; WIPI-1 alpha
Gene Aliases: 4930533H01Rik; ATG18; ATG18A; AW411817; D11Ertd498e; RGD1307754; WIPI1; WIPI49
UniProt ID: (Human) Q5MNZ9, (Mouse) Q8R3E3
Entrez Gene ID: (Human) 55062, (Rat) 303630, (Mouse) 52639
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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