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WIZ Antibody (A305-864A) in WB
Detection of human WIZ by western blot. Samples: Whole cell lysate (50 µg) from HEK293T, MCF-7, HeLa, LNCaP, and A-549 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-WIZ antibody (A305-864A-2 lot 1) used for WB at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A305-864A
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A region between residue 1601 and 1651 of human Protein Wiz.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate, tris citrate
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wiz; widely-interspaced zinc finger motifs; Widely-interspaced zinc finger-containing protein; WIZ zinc finger; Zinc finger protein 803
Gene Aliases: WIZ; ZNF803
UniProt ID: (Human) O95785, (Mouse) O88286
Entrez Gene ID: (Human) 58525, (Mouse) 22404
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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