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WNT10A Antibody (PA5-22155) in ICC/IF
WNT10A Polyclonal Antibody detects WNT10A protein at cytoplasm by immunofluorescent analysis. Sample: SKNSH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: WNT10A protein stained by WNT10A Polyclonal Antibody (Product # PA5-22155) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-22155
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 47 and 271 of WNT10A (Uniprot ID#Q9GZT5)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11154376
Product Specific Information
Recommended positive controls: Molt-4, Raji.
Predicted reactivity: Mouse (96%), Rat (97%), Chicken (82%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-10a; wingless-type MMTV integration site family member 10A; wingless-type MMTV integration site family, member 10A
Gene Aliases: OODD; SSPS; STHAG4; WNT10A
UniProt ID: (Human) Q9GZT5
Entrez Gene ID: (Human) 80326
hair follicle development
positive regulation of gene expression
neural crest cell differentiation
Wnt signaling pathway
neuron differentiation
hair follicle morphogenesis
odontogenesis
regulation of odontogenesis of dentin-containing tooth
tongue development
skin development
cell fate commitment
epidermis morphogenesis
sebaceous gland development
cellular response to transforming growth factor beta stimulus
Performance Guarantee
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