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Product Details
PA5-33112
Product Specifications
Species Reactivity
Bat,
Bovine,
Dog,
Human,
Non-human primate,
Rabbit
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from internal region of human WNT10A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550571
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bovine, Bat, Elephant, Panda, Rabbit (100%); Rat, Hamster, Opossum (94%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-10a; wingless-type MMTV integration site family member 10A; wingless-type MMTV integration site family, member 10A
Gene Aliases: OODD; SSPS; STHAG4; WNT10A
UniProt ID: (Human) Q9GZT5
Entrez Gene ID: (Dog) 488528, (Rabbit) 100352839, (Bovine) 537330, (Human) 80326
hair follicle development
positive regulation of gene expression
neural crest cell differentiation
Wnt signaling pathway
neuron differentiation
hair follicle morphogenesis
odontogenesis
regulation of odontogenesis of dentin-containing tooth
tongue development
skin development
cell fate commitment
epidermis morphogenesis
sebaceous gland development
cellular response to transforming growth factor beta stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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