Proteintech

WNT3A Polyclonal Antibody

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WNT3A Antibody (26744-1-AP) in WB

Fetal Human brain tissue were subjected to SDS PAGE followed by western blot with 26744-1-AP (WNT3A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Product Details

26744-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:600

View 17 publications 17 publications

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

WNT3A Fusion Protein Ag25051

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

267 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

Wnt3a, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

MicroRNA profiling reveals the role of miR-133b-3p in promoting apoptosis and inhibiting cell proliferation and testosterone synthesis in mouse TM3 cells.

In vitro cellular & developmental biology. Animal

Pan C,Fei Q,Jin J,Zheng J,Wu D,Li H,Huang X,Kong X

Sun Jan 01 00:00:00 EST 2023

The potential mechanism of qinghua quyu jianpi decoction in the treatment of ulcerative colitis based on network pharmacology and experimental validation.

Journal of ethnopharmacology

Qu F,Li D,Zhang S,Zhang C,Shen A

Wed Jun 28 00:00:00 EDT 2023

Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.

Acta pharmacologica Sinica

Wu H,Tang LX,Wang XM,Li LP,Chen XK,He YJ,Yang DZ,Shi Y,Shou JL,Zhang ZS,Wang L,Lu BJ,An SM,Zeng CY,Wang WE

Thu Jun 01 00:00:00 EDT 2023

NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.

Journal of gastrointestinal oncology

Yang H,Pu L,Li R,Zhu R

Sat Apr 29 00:00:00 EDT 2023

Compound heterozygous variants in WLS gene causes Zaki syndrome.

Clinical genetics

Yu C,Wang C,Zhou W,Zhang A,Jia Z,Zheng B,Ding G

Tue Aug 01 00:00:00 EDT 2023

Peptidase Inhibitor 16 Attenuates Left Ventricular Injury and Remodeling After Myocardial Infarction by Inhibiting the HDAC1-Wnt3a-β-Catenin Signaling Axis.

Journal of the American Heart Association

Wang L,Du A,Lu Y,Zhao Y,Qiu M,Su Z,Shu H,Shen H,Sun W,Kong X

Tue May 16 00:00:00 EDT 2023

XAV-939 inhibits epithelial-mesenchymal transformation in pulmonary fibrosis induced by crystalline silica via the Wnt signaling pathway.

Environmental toxicology

Lv Z,Xu H,Si X,Xu S,Li X,Li N,Zhou Q,Chang M,Yao S,Li H

Wed Feb 01 00:00:00 EST 2023

SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.

Apoptosis : an international journal on programmed cell death

Wu ZL,Chen YJ,Zhang GZ,Xie QQ,Wang KP,Yang X,Liu TC,Wang ZQ,Zhao GH,Zhang HH

Tue Feb 01 00:00:00 EST 2022

Insulin and liraglutide attenuate brain pathology in diabetic mice by enhancing the Wnt/β-catenin signaling pathway.

Experimental and therapeutic medicine

Zhao Y,Yu J,Ping F,Xu L,Li W,Zhang H,Li Y

Fri Jul 01 00:00:00 EDT 2022

High expression of NPM1 via the Wnt/β-catenin signalling pathway might predict poor prognosis for patients with prostate adenocarcinoma.

Clinical and experimental pharmacology & physiology

Ruan Y,Xu H,Ji X

Fri Apr 01 00:00:00 EDT 2022

The carbonic anhydrase inhibitor acetazolamide inhibits urinary bladder cancers via suppression of β-catenin signaling.

Cancer science

Matsue T,Gi M,Shiota M,Tachibana H,Suzuki S,Fujioka M,Kakehashi A,Yamamoto T,Kato M,Uchida J,Wanibuchi H

Mon Aug 01 00:00:00 EDT 2022

Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca²⁺-Activin A circuit in chronic cerebral hypoperfusion rats.

Aging

Zhang X,Shi X,Wang J,Xu Z,He J

Mon Aug 30 00:00:00 EDT 2021

MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.

Oncology reports

Chen ZQ,Yuan T,Jiang H,Yang YY,Wang L,Fu RM,Luo SQ,Zhang T,Wu ZY,Wen KM

Fri Oct 01 00:00:00 EDT 2021

Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.

Journal of Cancer

Yu J,Wang W,Liu B,Gu J,Chen S,Cui Y,Sun G

Tue Jun 08 00:00:00 EDT 2021

BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.

Journal of bone oncology

Guo H,Peng J,Hu J,Chang S,Liu H,Luo H,Chen X,Tang H,Chen Y

Wed Dec 01 00:00:00 EST 2021

BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu J,Shangguan Y,Sun J,Cong W,Xie Y

Tue Sep 01 00:00:00 EDT 2020

Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.

Bioscience reports

Li H,Wu W,He X,Cao C,Yu X,Zeng Y,Li L

Mon Sep 30 00:00:00 EDT 2019

Developmental exposure to nonylphenol induced rat axonal injury in vivo and in vitro.

Archives of toxicology

Li S,You M,Chai W,Xu Y,Wang Y

Sun Sep 01 00:00:00 EDT 2019

Bioinformatics

Protein Aliases: MGC119418; MGC119419; MGC119420; Protein Wnt-3a; vestigial tail; wingless-related MMTV integration site 3A; wingless-type MMTV integration site family member 3A; wingless-type MMTV integration site family, member 3A; Wnt 3a; WNT3A protein

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Gene Aliases: vt; Wnt-3a; WNT3A

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UniProt ID: (Human) P56704, (Mouse) P27467

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Entrez Gene ID: (Human) 89780, (Mouse) 22416

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Function(s)

transcription coactivator activity receptor binding frizzled binding frizzled-2 binding protein binding protein domain specific binding co-receptor binding receptor agonist activity intercellular signal molecule

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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WNT3A Polyclonal Antibody

WNT3A Antibody (26744-1-AP) in WB

Product Details

26744-1-AP

Western Blot (WB)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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