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WRCH-1 Antibody (BS-1944R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with WRCH-1 Polyclonal Antibody, Unconjugated (bs-1944R) at 1:400 overnight at 4°C, DAB staining.
Product Details
BS-1944R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human WRCH-1, amino acids 151-258.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310026M05Rik; CDC42-like GTPase 1; GTP-binding protein like 1; GTP-binding protein SB128; GTP-binding protein-like 1; ras homolog gene family, member U; ras-like gene family member U; Ras-like protein member U; Rho GTPase-like protein ARHU; Rho-related GTP-binding protein RhoU; RHOU; Ryu GTPase; similar to ras homolog gene family, member U; Wnt-1 responsive Cdc42 homolog 1; Wnt1 responsive Cdc42 homolog; WRCH-1
Gene Aliases: 2310026M05Rik; AI182090; ARHU; CDC42L1; G28K; hG28K; mG28K; RHOU; SB128; WRCH-1; WRCH1
UniProt ID: (Human) Q7L0Q8, (Mouse) Q9EQT3
Entrez Gene ID: (Rat) 678766, (Human) 58480, (Mouse) 69581
G1/S transition of mitotic cell cycle
cytoskeleton organization
regulation of cell shape
Rac protein signal transduction
actin cytoskeleton organization
regulation of small GTPase mediated signal transduction
positive regulation of protein targeting to mitochondrion
small GTPase mediated signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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