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YME1L1 Antibody (PA5-99974) in ICC/IF
Immunofluorescent analysis of YME1L1 in HepG2. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with YME1L1 polyclonal antibody (Product # PA5-99974) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-99974
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human YME1L1(Accession Q96TA2), corresponding to amino acid residues L648-L698.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818907
Product Specific Information
Antibody detects endogenous levels of total YME1L1.
Target Information
YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent metalloprotease FtsH1; ATP-dependent metalloprotease FtsH1 homolog; ATP-dependent metalloprotease YME1L1; ATP-dependent zinc metalloprotease YME1L1; Meg-4; PAMP; Presenilin-associated metalloprotease; YME1-like protein 1
Gene Aliases: FTSH; FTSH1; MEG4; PAMP; UNQ1868/PRO4304; YME1L; YME1L1
UniProt ID: (Human) Q96TA2, (Mouse) O88967
Entrez Gene ID: (Human) 10730, (Rat) 114217, (Mouse) 27377
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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