Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: GSEFDEMFV GVGASRIRNL FREAKANAPC VIFIDELDSV GGKRIESPMH PYSRQTINQL LAEMDGFKPN EGVIIIGATN FPEALDNALI RPGRFDMQVT VPRPDVKGRT EILKWYLNKI KFDQSVDPEI IARGTVGFSG AELENLVNQA ALKAAVDGKE MVTMKELEFS KDKILMGPER RSVEIDNKNK TITAYHESGH AIIAYYTKDA MPINKATIMP RGPTLGHVSL LPENDRWNET RAQLLAQMDV SMGGRVAEEL IFGTDHITTG ASSDFDNATK IAKRMVTKFG MSEKLGVMTY SDTGKLSPET QSAIEQEIRI LLRDSYERAK HILKTHAKEH KNLAEALLTY ETLDAKEIQI VLEGKKLEVR (348-716 aa encoded by BC023507)
YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent metalloprotease FtsH1; ATP-dependent metalloprotease FtsH1 homolog; ATP-dependent metalloprotease YME1L1; ATP-dependent zinc metalloprotease YME1L1; Meg-4; PAMP; Presenilin-associated metalloprotease; YME1-like protein 1
Gene Aliases: FTSH; FTSH1; MEG4; PAMP; UNQ1868/PRO4304; YME1L; YME1L1
UniProt ID: (Human) Q96TA2, (Mouse) O88967
Entrez Gene ID: (Human) 10730, (Rat) 114217, (Mouse) 27377
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