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ZBTB20 Antibody (PA5-96881) in WB
Western blot analysis of ZBTB20 in extracts of various cell lines. Samples were incubated with ZBTB20 Polyclonal antibody (Product # PA5-96881) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-96881
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human ZBTB20 (NP_0564573)
Conjugate
Form
Liquid
Concentration
1.18 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808683
Product Specific Information
Immunogen sequence: ILTAASILQI KTVIDECTRI VSQNVGDVFP GIQDSGQDTP RGTPESGTSG QSSDTESGYL QSHPQHSVDR IYSALYACSM QNGSGERSFY SGAVVSHHET ALGLPRDHHM EDPSWITRIH ERSQQMERYL STTPETTHCR KQPRPVRIQT LVGNIHIKQE MEDDYDYYGQ QRVQILERNE SEECTEDTDQ AEGTESEPKG ESFDSGVSSS IGTEPDSVEQ QFGPGAARDS QAEPTQPEQA AEAPAEGGPQ TNQLETGASS PERSNEVEMD STVITVSNSS DKSVLQQPSV NTSIGQPLPS T; Positive Samples: Jurkat, Mouse brain; Cellular Location: Nucleus
Target Information
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BTB/POZ domain zinc finger factor HOF; BTB/POZ zinc finger protein DPZF; dendritic cell-derived BTB/POZ zinc finger; Dendritic-derived BTB/POZ zinc finger protein; POZ/zinc finger transcription factor ODA-8; Zinc finger and BTB domain-containing protein 20; Zinc finger protein 288
Gene Aliases: 1300017A20Rik; 7330412A13Rik; A930017C21Rik; D16Wsu73e; DPZF; HOF; ODA-8S; Oda8; PRIMS; RGD1560387; ZBTB20; Zfp288; ZNF288
UniProt ID: (Human) Q9HC78, (Mouse) Q8K0L9
Entrez Gene ID: (Human) 26137, (Rat) 288105, (Mouse) 56490
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
positive regulation of interferon-beta production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
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