Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAAESDVLHF QFEQQGDVVL QKMNLLRQQN LFCDVSIYIN DTEFQGHKVI LAACSTFMRD QFLLTQSKHV RITILQSAEV GRKLLLSCYT GALEVKRKEL LKYLTAASYL QMVHIVEKCT EALSKYLEID LSMKNNNQHT DLCQSSDPDV KNEDENSDKD CEIIEISEDS PVNIDFHVKE EESNALQSTV ESLTSERKEM KSPELSTVDI GFKDNEICIL HVESISTAGV ENGQFSQPCT SSKASMYFSE TQHSLINSTV ESRVAEVPGN QDQGLFCENT EGSYGTVSEI QNLEEGYSLR HQCPRCPRGF LHVENYLRHL KMHKLFLCLQ CGKTFTQKKN LNRHIRGHMG IRPFQCTVCL KTFTAKSTLQ DHLNIHSGDR PYKCHCCDMD FKHKSALKKH LTSVHGRSSG EKLSRPDLKR QSLL
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB6, also known as ZNF482, is highly expressed in brain. While little is known about ZBTB6, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB family member, ZBTB5, also acts as a transcriptional repressor, and can interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, suggesting that ZBTB6 may also act as a transcriptional repressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Zinc finger and BTB domain-containing protein 6; Zinc finger protein 482; Zinc finger protein with interaction domain
Gene Aliases: ZBTB6; ZID; ZNF482
UniProt ID: (Human) Q15916
Entrez Gene ID: (Human) 10773
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