Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEISSHQSHL LQQLNEQRRQ DVFCDCSILV EGKVFKAHRN VLFASSGYFK MLLSQNSKET SQPTTATFQA FSPDTFTVIL DFVYSGKLSL TGQNVIEVMS AASFLQMTDV ISVCKTFIKS SLDISEKEKD RYFSLSDKDA NSNGVERSSF YSGGWQEGSS SPRSHLSPEQ GTGIISGKSW NKYNYHPASQ KNTQQPLAKH EPRKESIKKT KHLRLSQPSE VTHYKSSKRE VRTSDSSSHV SQSEEQAQID AEMDSTPVGY QYGQGSDVTS KSFPDDLPRM RFKCPYCTHV VKRKADLKRH LRCHTGERPY PCQACGKRFS RLDHLSSHFR TIHQACKLIC RKCKRHVTDL TGQVVQEGTR RYRLCNECLA EFGIDSLPID LEAEQHLMSP SDGDKDSRWH LSEDENRSYV EIVEDGSADL VIQQVDDSEE EEEKEIKPNI R
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BOZ-F1; BTB/POZ and zinc-finger domain-containing factor; BTB/POZ and zinc-finger domains factor on chromosome 1; zinc finger and BTB domain containing 8; Zinc finger and BTB domain-containing protein 8A
Gene Aliases: BOZF1; ZBTB8; ZBTB8A; ZNF916A
UniProt ID: (Human) Q96BR9
Entrez Gene ID: (Human) 653121
Molecular Function:
non-motor actin binding protein
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