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Product Details
PA5-58965
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ZDHHC16. Recombinant protein control fragment (Product #RP-91045).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2649853
Product Specific Information
Immunogen sequence: VLISRGETSI ERHINKKERR RLQAKGRVFR NPYNYGCLDN WKVFLGVDTG RHWLTRVLLP SSHLPHGNGM SWEPPPWVTA
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one DHHC-type zinc finger. Existing as multiple alternatively spliced isoforms, ZDHHC16 interacts with c-Abl and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Via its association with c-Abl, ZDHHC16 may be involved in the regulation of apoptosis. The gene encoding ZDHHC16 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abl-philin 2; DHHC-16; Palmitoyltransferase ZDHHC16; Zinc finger DHHC domain-containing protein 16; zinc finger, DHHC domain containing 16; zinc finger, DHHC-type containing 16
Gene Aliases: APH2; DHHC-16; UNQ2570/PRO6258; ZDHHC16
UniProt ID: (Human) Q969W1
Entrez Gene ID: (Human) 84287
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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