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FIGURE: 1 / 1
Positive Samples: HeLa, MCF7, SKOV3, A-549, Mouse brain, Mouse lung, Mouse testis, Rat brain, Rat lung
Immunogen sequence: VFGDEKKYWL LPIFSSLGDG CSFPTRLVGM DPEQASVTNQ NEYARSSGSN QPFPIKPLSE SKNRLLDSES QWLENGAEEG IVKSGTNNHV TVAIEN
Catalyzes palmitoylation of Cys residues on target proteins (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245). [UniProt]
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Protein Aliases: Acyltransferase ZDHHC20; DHHC domain-containing cysteine-rich protein 20; DHHC-20; DHHC-containing protein 20; DHHC20; membrane-associated DHHC24 zinc finger protein; Palmitoyltransferase ZDHHC20; probable palmitoyltransferase ZDHHC20; Zinc finger DHHC domain-containing protein 20; zinc finger, DHHC domain containing 20; zinc finger, DHHC-type containing 20
Gene Aliases: 4933421L13Rik; 5033406L14Rik; AI448102; B230110O18Rik; DHHC-20; HK11; RGD1305755; ZDHHC20
UniProt ID: (Human) Q5W0Z9, (Mouse) Q5Y5T1
Entrez Gene ID: (Human) 253832, (Rat) 305923, (Mouse) 75965
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