Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The antibody detects endogenous levels of total ZFHX3 protein.
Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer. Miura Y., J. Biol. Chem. 270:26840-26848(1995). Morinaga T., Mol. Cell. Biol. 11:6041-6049(1991). Martin J., Nature 432:988-994(2004).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha-fetoprotein enhancer binding protein; Alpha-fetoprotein enhancer-binding protein; AT motif binding factor 1; AT motif-binding factor 1; AT-binding transcription factor 1; ZFH-3; Zinc finger homeobox protein 3; Zinc finger homeodomain protein 3
Gene Aliases: A230102L03Rik; ATBF1; ATBT; C16orf47; mKIAA4228; WBP9; ZFHX3; ZNF927
UniProt ID: (Human) Q15911
Entrez Gene ID: (Human) 463, (Mouse) 11906
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