Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.
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Protein Aliases: Zinc finger MYM-type protein 3; Zinc finger protein 261; zinc finger, MYM-type 3
Gene Aliases: DXS6673E; KIAA0385; MYM; XFIM; ZMYM3; ZNF198L2; ZNF261
UniProt ID: (Human) Q14202
Entrez Gene ID: (Human) 9203
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