Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: APWMVEPVRRR RAPDSGSKCE TKKLPPNQCN KSGQSICQKL VSAQQKAPTR KSGCNKNSVL VKPKKGHSGK
Highest antigen sequence identity to the following orthologs - mouse 66%, rat 70%.
Mipu1, also known as zinc finger protein 667 or ZNF667, encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain. This protein is highly expressed in heart and brain and is upregulated in rat heart after a transient ischemia-reperfusion procedure. Overexpression experiments suggest that Mipu1 suppresses the transcriptional activities of AP-1 and SRE in the MAPK signaling pathway and thus may play a role in the pathogenesis of cardiac and vascular disease. At least four isoforms of MIPU1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: myocardial ischemic preconditioning upregulated 1 ortholog; Zinc finger protein 667
Gene Aliases: MIPU1; ZNF667
UniProt ID: (Human) Q5HYK9
Entrez Gene ID: (Human) 63934
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