Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is predicted to react with non-human primate based on sequence homology.
Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DUB; Lys-63-specific deubiquitinase ZUFSP; zinc finger with UFM1-specific peptidase domain; Zinc finger with UFM1-specific peptidase domain protein; Zinc finger-containing ubiquitin peptidase 1
Gene Aliases: 2700019D07Rik; C6orf113; dJ412I7.3; ZUFSP; ZUP1
UniProt ID: (Human) Q96AP4, (Mouse) Q3T9Z9
Entrez Gene ID: (Human) 221302, (Mouse) 72580, (Chinese hamster) 100771141
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