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ZnT6 Polyclonal Antibody

View all (8) SLC30A6 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (2)

ZnT6 Antibody in Western Blot (WB)

ZnT6 Antibody in Western Blot (WB)

FIGURE: 1 / 2

ZnT6 Antibody (13526-1-AP) in WB

K-562 cells were subjected to SDS PAGE followed by western blot with 13526-1-AP (ZnT6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

ZnT6 Antibody in Western Blot (WB)

ZnT6 Antibody in Western Blot (WB)

Product Image Gallery

ZnT6 Antibody in Western Blot (WB) — K-562 cells were subjected to SDS PAGE followed by western blot with 13526-1-AP (ZnT6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

ZnT6 Antibody in Western Blot (WB) — A375 cells were subjected to SDS PAGE followed by western blot with 13526-1-AP (ZnT6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

13526-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 7 publications 7 publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ZnT6 Fusion Protein Ag4403 (286-501 aa encoded by BC032525)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSVYSGKVL LQTTPPHVIG QLDKLIREVS TLDGVLEVRN EHFWTLGFGS LAGSVHVRIR RDANEQMVLA HVTNRLYTLV STLTVQIFKD DWIRPALLSG PVAANVLNFS DHHVIPMPLL KGTDDLNPVT STPAKPSSPP PEFSFNTPGK NVNPVILLNT QTRPYGFGLN HGHTPYSSML NQGLGVPGIG ATQGLRTGFT NIPSRYGTNN RIGQPRP (286-501 aa encoded by BC032525 )

Target Information

Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc (Seve et al., 2004).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Transcriptional responses of four slc30a/znt family members and their roles in Zn homeostatic modulation in yellow catfish Pelteobagrus fulvidraco.

Biochimica et biophysica acta. Gene regulatory mechanisms

Song CC,Chen GH,Zhong CC,Chen F,Chen SW,Luo Z

Sun Aug 01 00:00:00 EDT 2021

Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation.

The Journal of biological chemistry

Suzuki E,Ogawa N,Takeda TA,Nishito Y,Tanaka YK,Fujiwara T,Matsunaga M,Ueda S,Kubo N,Tsuji T,Fukunaka A,Yamazaki T,Taylor KM,Ogra Y,Kambe T

Fri Apr 24 00:00:00 EDT 2020

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.

Journal of neuroscience research

Kaneko M,Noguchi T,Ikegami S,Sakurai T,Kakita A,Toyoshima Y,Kambe T,Yamada M,Inden M,Hara H,Oyanagi K,Inuzuka T,Takahashi H,Hozumi I

Sun Feb 01 00:00:00 EST 2015

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.

Journal of neuroscience research

Kaneko M,Noguchi T,Ikegami S,Sakurai T,Kakita A,Toyoshima Y,Kambe T,Yamada M,Inden M,Hara H,Oyanagi K,Inuzuka T,Takahashi H,Hozumi I

Sun Feb 01 00:00:00 EST 2015

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.

Journal of neuroscience research

Kaneko M,Noguchi T,Ikegami S,Sakurai T,Kakita A,Toyoshima Y,Kambe T,Yamada M,Inden M,Hara H,Oyanagi K,Inuzuka T,Takahashi H,Hozumi I

Sun Feb 01 00:00:00 EST 2015

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.

Journal of neuroscience research

Kaneko M,Noguchi T,Ikegami S,Sakurai T,Kakita A,Toyoshima Y,Kambe T,Yamada M,Inden M,Hara H,Oyanagi K,Inuzuka T,Takahashi H,Hozumi I

Sun Feb 01 00:00:00 EST 2015

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.

Journal of neuroscience research

Kaneko M,Noguchi T,Ikegami S,Sakurai T,Kakita A,Toyoshima Y,Kambe T,Yamada M,Inden M,Hara H,Oyanagi K,Inuzuka T,Takahashi H,Hozumi I

Sun Feb 01 00:00:00 EST 2015

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.

Journal of neuroscience research

Kaneko M,Noguchi T,Ikegami S,Sakurai T,Kakita A,Toyoshima Y,Kambe T,Yamada M,Inden M,Hara H,Oyanagi K,Inuzuka T,Takahashi H,Hozumi I

Sun Feb 01 00:00:00 EST 2015

Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?

Metallomics : integrated biometal science

Grubman A,Pollari E,Duncan C,Caragounis A,Blom T,Volitakis I,Wong A,Cooper J,Crouch PJ,Koistinaho J,Jalanko A,White AR,Kanninen KM

Tue Apr 01 00:00:00 EDT 2014

Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?

Metallomics : integrated biometal science

Grubman A,Pollari E,Duncan C,Caragounis A,Blom T,Volitakis I,Wong A,Cooper J,Crouch PJ,Koistinaho J,Jalanko A,White AR,Kanninen KM

Tue Apr 01 00:00:00 EDT 2014

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.

Acta neuropathologica communications

Grubman A,Lidgerwood GE,Duncan C,Bica L,Tan JL,Parker SJ,Caragounis A,Meyerowitz J,Volitakis I,Moujalled D,Liddell JR,Hickey JL,Horne M,Longmuir S,Koistinaho J,Donnelly PS,Crouch PJ,Tammen I,White AR,Kanninen KM

Fri Feb 28 00:00:00 EST 2014

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.

Acta neuropathologica communications

Grubman A,Lidgerwood GE,Duncan C,Bica L,Tan JL,Parker SJ,Caragounis A,Meyerowitz J,Volitakis I,Moujalled D,Liddell JR,Hickey JL,Horne M,Longmuir S,Koistinaho J,Donnelly PS,Crouch PJ,Tammen I,White AR,Kanninen KM

Fri Feb 28 00:00:00 EST 2014

Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.

Biology open

Kanninen KM,Grubman A,Caragounis A,Duncan C,Parker SJ,Lidgerwood GE,Volitakis I,Ganio G,Crouch PJ,White AR

Sat Jun 15 00:00:00 EDT 2013

Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.

Biology open

Kanninen KM,Grubman A,Caragounis A,Duncan C,Parker SJ,Lidgerwood GE,Volitakis I,Ganio G,Crouch PJ,White AR

Sat Jun 15 00:00:00 EDT 2013

Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway.

The Journal of biological chemistry

Fukunaka A,Kurokawa Y,Teranishi F,Sekler I,Oda K,Ackland ML,Faundez V,Hiromura M,Masuda S,Nagao M,Enomoto S,Kambe T

Fri May 06 00:00:00 EDT 2011

Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway.

The Journal of biological chemistry

Fukunaka A,Kurokawa Y,Teranishi F,Sekler I,Oda K,Ackland ML,Faundez V,Hiromura M,Masuda S,Nagao M,Enomoto S,Kambe T

Fri May 06 00:00:00 EDT 2011

Bioinformatics

Protein Aliases: solute carrier family 30 (zinc transporter), member 6; Solute carrier family 30 member 6; Zinc transporter 6; ZnT-6

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Gene Aliases: MST103; MSTP103; SLC30A6; ZNT6

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UniProt ID: (Human) Q6NXT4

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Entrez Gene ID: (Human) 55676

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zinc ion transmembrane transporter activity transporter

Process(es)

response to zinc ion regulation of sequestering of zinc ion zinc II ion transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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