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Invitrogen
alpha Galactosidase Polyclonal Antibody
FIGURE: 1 / 1
alpha Galactosidase Antibody (PA1-9528) in WB
PloS one 2016 -
Fig 4 Western Blot of purified WT and mutant alphaGal. Purified WT and mutant enzymes were subjected to Western blotting using a polyclonal antibody raised against residues 55-64 and 396-407 of alpha Gal. (a) Blot at shorter and (b) longer exposure.
Product Details
PA1-9528
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Bacteria
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
Mix of synthetic peptides corresponding to residues 55-64 and 396-407 of human alpha Galactosidase
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
IgY fraction
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2263438
Product Specific Information
PA1-9528 detects Alpha Galactosidase in human samples.
PA1-9528 has been successfully used in Western blot and ELISA procedures.
The PA1-9528 immunogen is a mix of synthetic peptides corresponding to residues 55-64 and 396-407 of human alpha Galactosidase.
Store at 4ºC for one week, and -20ºC for long term storage.
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: agalsidase alfa; Alpha-D-galactosidase A; Alpha-D-galactoside galactohydrolase; alpha-D-galactoside galactohydrolase 1; alpha-gal A; Alpha-galactosidase A; galactosidase, alpha; Galactosylgalactosylglucosylceramidase GLA; Melibiase
Gene Aliases: GALA; GLA
UniProt ID: (Human) P06280
Entrez Gene ID: (Human) 2717
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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