Product References
The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes.
The Journal of biological chemistry
Song L,Wang D,Abbas G,Li M,Cui M,Wang J,Lin Z,Zhang XE
Wed Mar 01 00:00:00 EST 2023
Acetyl-CoA Acetyltransferase 2 Confers Radioresistance by Inhibiting Ferroptosis in Esophageal Squamous Cell Carcinoma.
International journal of radiation oncology, biology, physics
Heng J,Li Z,Liu L,Zheng Z,Zheng Y,Xu X,Liao L,Xu H,Huang H,Li E,Xu L
Wed Nov 15 00:00:00 EST 2023
LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.
Journal of ovarian research
Dey G,Bharti R,Braley C,Alluri R,Esakov E,Crean-Tate K,McCrae K,Joehlin-Price A,Rose PG,Lathia J,Gong Z,Reizes O
Tue Jun 27 00:00:00 EDT 2023
Co-Expression of Chromatin Assembly Factor 1 Subunit A and Proliferating Cell Nuclear Antigen Is a Prognostic Biomarker of Esophageal Cancer.
Biomedicines
Wen B,Deng DX,Liao LD,Zhang ZD,Zheng YQ,Dong K,Xu LY,Li EM
Sun Apr 16 00:00:00 EDT 2023
BmCBP Catalyzes the Acetylation of BmApoLp-II Protein and Regulates Its Stability in Silkworm, Bombyx mori.
Insects
Chen Y,Lv J,Zu G,Yang F,Geng J,You Z,Jiang C,Sheng Q,Nie Z
Thu Mar 23 00:00:00 EDT 2023
Wnt4 and ephrinB2 instruct apical constriction via Dishevelled and non-canonical signaling.
Nature communications
Yoon J,Sun J,Lee M,Hwang YS,Daar IO
Fri Jan 20 00:00:00 EST 2023
Alphavirus infection triggers antiviral RNAi immunity in mammals.
Cell reports
Kong J,Bie Y,Ji W,Xu J,Lyu B,Xiong X,Qiu Y,Zhou X
Tue May 30 00:00:00 EDT 2023
FAM122A Is Required for Mesendodermal and Cardiac Differentiation of Embryonic Stem Cells.
Stem cells (Dayton, Ohio)
Yang YS,Liu MH,Yan ZW,Chen GQ,Huang Y
Tue Apr 25 00:00:00 EDT 2023
Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling.
The Journal of experimental medicine
Andreani V,Ramamoorthy S,Fässler R,Grosschedl R
Mon Jan 02 00:00:00 EST 2023
Chemotherapeutic drugs-induced pyroptosis mediated by gasdermin E promotes the progression and chemoresistance of pancreatic cancer.
Cancer letters
Li S,Yue M,Xu H,Zhang X,Mao T,Quan M,Ma J,Wang Y,Ge W,Wang Y,Xue S,Shentu D,Cui J,Wang L
Wed Jun 28 00:00:00 EDT 2023
The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function.
Journal of cell science
Critchley WR,Smith GA,Zachary IC,Harrison MA,Ponnambalam S
Mon May 15 00:00:00 EDT 2023
Sitravatinib as a potent FLT3 inhibitor can overcome gilteritinib resistance in acute myeloid leukemia.
Biomarker research
Zhang Y,Wang P,Wang Y,Shen Y
Tue Jan 24 00:00:00 EST 2023
Isoliquiritigenin inhibits virus replication and virus-mediated inflammation via NRF2 signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang H,Jia X,Zhang M,Cheng C,Liang X,Wang X,Xie F,Wang J,Yu Y,He Y,Dong Q,Wang Y,Xu A
Thu Jun 01 00:00:00 EDT 2023
An extracellular vesicle targeting ligand that binds to Arc proteins and facilitates Arc transport in vivo.
eLife
Lee PH,Anaya M,Ladinsky MS,Reitsma JM,Zinn K
Fri Jun 16 00:00:00 EDT 2023
TGF-β1 activates neutrophil signaling and gene expression but not migration.
bioRxiv : the preprint server for biology
Hein LE,SenGupta S,Gunasekaran G,Johnson C,Parent CA
Sat May 27 00:00:00 EDT 2023
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
The FEBS journal
Hao Z,Yuan Q,Tang H,Lei C,Chen Y,Su H,Zhang C
Tue Aug 01 00:00:00 EDT 2023
Brain heterotopia formation by ciliopathic breakdown of neuroepithelial and blood-cerebrospinal fluid barriers.
Brain pathology (Zurich, Switzerland)
Jung HJ,Yeo S,Jang J,Pleasure S,Choe Y
Sat Jul 01 00:00:00 EDT 2023
Cisplatin-induced pyroptosis is mediated via the CAPN1/CAPN2-BAK/BAX-caspase-9-caspase-3-GSDME axis in esophageal cancer.
Chemico-biological interactions
Li RY,Zheng ZY,Li ZM,Heng JH,Zheng YQ,Deng DX,Xu XE,Liao LD,Lin W,Xu HY,Huang HC,Li EM,Xu LY
Fri Jul 01 00:00:00 EDT 2022
A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.
Cell stem cell
Du J,Zheng L,Gao P,Yang H,Yang WJ,Guo F,Liang R,Feng M,Wang Z,Zhang Z,Bai L,Bu Y,Xing S,Zheng W,Wang X,Quan L,Hu X,Wu H,Chen Z,Chen L,Wei K,Zhang Z,Zhu X,Zhang X,Tu Q,Zhao SM,Lei X,Xiong JW
Thu Apr 07 00:00:00 EDT 2022
ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin's lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway.
Chemico-biological interactions
Ma C,Liu M,Zhang J,Cai H,Wu Y,Zhang Y,Ji Y,Shan H,Zou Z,Yang L,Liu L,Xu H,Lei H,Liu C,Zhou L,Cao Y,Zhou H,Wu Y
Wed Jan 05 00:00:00 EST 2022
Interference in melanoma CD248 function reduces vascular mimicry and metastasis.
Journal of biomedical science
Kuo CH,Wu YF,Chang BI,Hsu CK,Lai CH,Wu HL
Fri Nov 18 00:00:00 EST 2022
Pharmacological Inhibition of Class III Alcohol Dehydrogenase 5: Turning Remote Ischemic Conditioning Effective in a Diabetic Stroke Model.
Antioxidants (Basel, Switzerland)
Zaidi SK,Hoda MN,Tabrez S,Khan MI
Tue Oct 18 00:00:00 EDT 2022
DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells.
The Journal of investigative dermatology
Kamada H,Yasuhira S,Shibazaki M,Amano H,Maesawa C
Thu Sep 01 00:00:00 EDT 2022
Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development.
Cell reports
Sun J,Yoon J,Lee M,Lee HK,Hwang YS,Daar IO
Tue Feb 01 00:00:00 EST 2022
Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration.
Nucleic acids research
Zhang Q,Wang S,Li W,Yau E,Hui H,Singh PK,Achuthan V,Young Karris MA,Engelman AN,Rana TM
Fri Jul 08 00:00:00 EDT 2022
Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.
Cell reports
Ding P,Xu Y,Li L,Lv X,Li L,Chen J,Zhou D,Wang X,Wang Q,Zhang W,Liao T,Ji QH,Lei QY,Hu W
Tue May 31 00:00:00 EDT 2022
Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation.
PloS one
Thevkar-Nagesh P,Habault J,Voisin M,Ruff SE,Ha S,Ruoff R,Chen X,Rawal S,Zahr T,Szabo G,Rogatsky I,Fisher EA,Garabedian MJ
Thu Sep 08 00:00:00 EDT 2022
XBP1 variant 1 promotes mitosis of cancer cells involving upregulation of the polyglutamylase TTLL6.
Human molecular genetics
Zhong Y,Yan W,Ruan J,Fang M,Yu C,Du S,Rai G,Tao D,Henderson MJ,Fang S
Wed Aug 17 00:00:00 EDT 2022
Echovirus 11 infection induces pyroptotic cell death by facilitating NLRP3 inflammasome activation.
PLoS pathogens
Wang C,Yang R,Yang F,Han Y,Ren Y,Xiong X,Wang X,Bi Y,Li L,Qiu Y,Xu Y,Zhou X
Mon Aug 01 00:00:00 EDT 2022
TNFα activation and TGFβ blockage act synergistically for smooth muscle cell calcification in patients with venous thrombosis via TGFβ/ERK pathway.
Journal of cellular and molecular medicine
Wang P,Pan Y,Yang C,Zhang L,Zhao Z,Ye K,Li L,Xia S,Lu X,Shi H,Li W,Yin M
Mon Aug 01 00:00:00 EDT 2022
Transcription Factor ASCL1 Acts as a Novel Potential Therapeutic Target for the Treatment of the Cushing's Disease.
The Journal of clinical endocrinology and metabolism
Chen Z,Jia Q,Zhao Z,Zhang Q,Chen Y,Qiao N,Ye Z,Ji C,Zhang Y,He W,Shi C,Cai Y,Yao B,Han R,Wang Y,Shou X,Shen M,Cao X,Zhou X,Cheng H,Zhu J,Hu Y,Zhang Z,Ye H,Li Y,Li S,Wang Y,Ma Z,Ni T,Zhao Y
Thu Jul 14 00:00:00 EDT 2022
Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.
The Journal of biological chemistry
Wang X,Yang Y,Zhao D,Zhang S,Chen Y,Chen Y,Feng K,Li X,Han J,Iwakiri Y,Duan Y,Yang X
Tue Feb 01 00:00:00 EST 2022
ORMDL3 regulates cigarette smoke-induced endoplasmic reticulum stress in airway smooth muscle cells.
The Journal of allergy and clinical immunology
Chen R,Michaeloudes C,Liang Y,Bhavsar PK,Chung KF,Ip MSM,Mak JCW
Fri Apr 01 00:00:00 EDT 2022
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway.
Cell death & disease
Qiu Z,Wang X,Yang Z,Liao S,Dong W,Sun T,Wu H,Zhang Q,Pan Z,Lam SM,Shui G,Jin J
Mon May 30 00:00:00 EDT 2022
Bombyx mori cypovirus (BmCPV) induces PINK1-Parkin mediated mitophagy via interaction of VP4 with host Tom40.
Developmental and comparative immunology
Zhu M,Pan J,Zhang M,Tong X,Zhang Y,Zhang Z,Liang Z,Zhang X,Hu X,Xue R,Cao G,Gong C
Sat Jan 01 00:00:00 EST 2022
Aging Impairs Adaptive Unfolded Protein Response and Drives Beta Cell Dedifferentiation in Humans.
The Journal of clinical endocrinology and metabolism
Song J,Ni Q,Sun J,Xie J,Liu J,Ning G,Wang W,Wang Q
Fri Nov 25 00:00:00 EST 2022
Retinal neurodegeneration in a mouse model of green-light-induced myopia.
Experimental eye research
Ji S,Ye L,Zhang L,Xu D,Dai J
Sat Oct 01 00:00:00 EDT 2022
Branched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming.
Frontiers in immunology
Cai Z,Li W,Brenner M,Bahiraii S,Heiss EH,Weckwerth W
Tue Nov 01 00:00:00 EDT 2022
From Initiation to Maintenance: HIV-1 Gp120-induced Neuropathic Pain Exhibits Different Molecular Mechanisms in the Mouse Spinal Cord Via Bioinformatics Analysis Based on RNA Sequencing.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Huang J,Lin F,Hu Y,Bloe CB,Wang D,Zhang W
Thu Dec 01 00:00:00 EST 2022
Very-low-density lipoprotein receptor-enhanced lipid metabolism in pancreatic stellate cells promotes pancreatic fibrosis.
Immunity
Yang X,Chen J,Wang J,Ma S,Feng W,Wu Z,Guo Y,Zhou H,Mi W,Chen W,Yin B,Lin Y
Tue Jul 12 00:00:00 EDT 2022
Long noncoding RNA DIO3OS induces glycolytic-dominant metabolic reprogramming to promote aromatase inhibitor resistance in breast cancer.
Nature communications
Chen X,Luo R,Zhang Y,Ye S,Zeng X,Liu J,Huang D,Liu Y,Liu Q,Luo ML,Song E
Tue Nov 22 00:00:00 EST 2022
PINCH-1 promotes IGF-1 receptor expression and skin cancer progression through inhibition of the GRB10-NEDD4 complex.
Theranostics
Wang X,Wang R,Jiang K,Zhu M,Guo L,Wu C
Tue Apr 12 00:00:00 EDT 2022
Involvement of SIRT3-GSK3β deacetylation pathway in the effects of maternal diabetes on oocyte meiosis.
Cell proliferation
Xin Y,Jin Y,Ge J,Huang Z,Han L,Li C,Wang D,Zhu S,Wang Q
Fri Jan 01 00:00:00 EST 2021
100 Hz Electroacupuncture Alleviated Chronic Itch and GRPR Expression Through Activation of Kappa Opioid Receptors in Spinal Dorsal Horn.
Frontiers in neuroscience
Li HP,Wang XY,Chen C,Li JJ,Yu C,Lin LX,Yu ZE,Jin ZY,Zhu H,Xiang HC,Hu XF,Cao J,Jing XH,Li M
Thu Apr 21 00:00:00 EDT 2022
LIM domain-containing 2 (LIMD2) promotes the progress of ovarian cancer via the focal adhesion signaling pathway.
Bioengineered
Chen L,Qian J,You Q,Ma J
Wed Dec 01 00:00:00 EST 2021
Selective HSP90β inhibition results in TNF and TRAIL mediated HIF1α degradation.
Immunobiology
Heck AL,Mishra S,Prenzel T,Feulner L,Achhammer E,Särchen V,Blagg BSJ,Schneider-Brachert W,Schütze S,Fritsch J
Mon Mar 01 00:00:00 EST 2021
GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner.
Cell death & disease
Xia Z,Zhang X,Liu P,Zhang R,Huang Z,Li D,Xiao X,Wu M,Ning N,Zhang Q,Zhang J,Liu M,Jiao B,Ren R
Sat Jan 09 00:00:00 EST 2021
SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes.
Frontiers in cell and developmental biology
Giordano I,Pirone L,Muratore V,Landaluze E,Pérez C,Lang V,Garde-Lapido E,Gonzalez-Lopez M,Barroso-Gomila O,Vertegaal ACO,Aransay AM,Rodriguez JA,Rodriguez MS,Sutherland JD,Barrio R
Sat Oct 09 00:00:00 EDT 2021
FAM122A promotes acute myeloid leukemia cell growth through inhibiting PP2A activity and sustaining MYC expression.
Haematologica
Liu MH,Chen J,Yang YS,Wang YQ,Chen GQ,Zhang Y,Huang Y
Mon Mar 01 00:00:00 EST 2021
Characterizing the distributions of IDO-1 expressing macrophages/microglia in human and murine brains and evaluating the immunological and physiological roles of IDO-1 in RAW264.7/BV-2 cells.
PloS one
Ji R,Ma L,Chen X,Sun R,Zhang L,Saiyin H,Wei W
Thu Dec 23 00:00:00 EST 2021
Heterologous prime-boost immunizations with chimpanzee adenoviral vectors elicit potent and protective immunity against SARS-CoV-2 infection.
Cell discovery
Liu J,Xu K,Xing M,Zhuo Y,Guo J,Du M,Wang Q,An Y,Li J,Gao P,Wang Y,He F,Guo Y,Li M,Zhang Y,Zhang L,Gao GF,Dai L,Zhou D
Sat Dec 18 00:00:00 EST 2021
RAB27A-dependent release of exosomes by liver cancer stem cells induces Nanog expression in their differentiated progenies and confers regorafenib resistance.
Journal of gastroenterology and hepatology
Huang H,Hou J,Liu K,Liu Q,Shen L,Liu B,Lu Q,Zhang N,Che L,Li J,Jiang S,Wang B,Wen Q,Hu L,Gao J
Wed Dec 01 00:00:00 EST 2021
Design, synthesis and bioactivity study on 5-phenylfuran derivatives as potent reversal agents against P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cell.
European journal of medicinal chemistry
Li YS,Yang X,Zhao DS,Cai Y,Huang Z,Wu R,Wang SJ,Liu GJ,Wang J,Bao XZ,Ye XY,Wei B,Cui ZN,Wang H
Thu Apr 15 00:00:00 EDT 2021
Regulation of local GTP availability controls RAC1 activity and cell invasion.
Nature communications
Bianchi-Smiraglia A,Wolff DW,Marston DJ,Deng Z,Han Z,Moparthy S,Wombacher RM,Mussell AL,Shen S,Chen J,Yun DH,O'Brien Cox A,Furdui CM,Hurley E,Feltri ML,Qu J,Hollis T,Kengne JBN,Fongang B,Sousa RJ,Kandel ME,Kandel ES,Hahn KM,Nikiforov MA
Tue Oct 19 00:00:00 EDT 2021
Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.
Frontiers in cell and developmental biology
Zhou B,Xiao M,Hu H,Pei X,Xue Y,Miao G,Wang J,Li W,Du Y,Zhang P,Wei T
Tue Aug 10 00:00:00 EDT 2021
miR-198 inhibits the progression of renal cell carcinoma by targeting BIRC5.
Cancer cell international
Yuan C,Su Z,Liao S,Li D,Zhou Z,Wang Y,Quan M,Zeng L,Lv C,Shen C,Gong W,Wu J,Chen X,Hu W,Lv X,Si W,Yu X
Wed Jul 21 00:00:00 EDT 2021
PINCH-1 promotes Δ1-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
Amino acids
Cui C,Wang J,Guo L,Wu C
Wed Dec 01 00:00:00 EST 2021
Mitochondrial dysfunction caused by novel ATAD3A mutations.
Molecular genetics and metabolism
Dorison N,Gaignard P,Bayot A,Gelot A,Becker PH,Fourati S,Lebigot E,Charles P,Wai T,Therond P,Slama A
Wed Jun 30 00:00:00 EDT 2021
Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase.
Cell chemical biology
Wu X,Spence JS,Das T,Yuan X,Chen C,Zhang Y,Li Y,Sun Y,Chandran K,Hang HC,Peng T
Thu May 21 00:00:00 EDT 2020
Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria.
Cell
Yang R,Mele F,Worley L,Langlais D,Rosain J,Benhsaien I,Elarabi H,Croft CA,Doisne JM,Zhang P,Weisshaar M,Jarrossay D,Latorre D,Shen Y,Han J,Ogishi M,Gruber C,Markle J,Al Ali F,Rahman M,Khan T,Seeleuthner Y,Kerner G,Husquin LT,Maclsaac JL,Jeljeli M,Errami A,Ailal F,Kobor MS,Oleaga-Quintas C,Roynard M,Bourgey M,El Baghdadi J,Boisson-Dupuis S,Puel A,Batteux F,Rozenberg F,Marr N,Pan-Hammarström Q,Bogunovic D,Quintana-Murci L,Carroll T,Ma CS,Abel L,Bousfiha A,Di Santo JP,Glimcher LH,Gros P,Tangye SG,Sallusto F,Bustamante J,Casanova JL
Wed Dec 23 00:00:00 EST 2020
Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol.
The EMBO journal
Wang S,Li W,Hui H,Tiwari SK,Zhang Q,Croker BA,Rawlings S,Smith D,Carlin AF,Rana TM
Mon Nov 02 00:00:00 EST 2020
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer.
Nature communications
Xu Q,Li Y,Gao X,Kang K,Williams JG,Tong L,Liu J,Ji M,Deterding LJ,Tong X,Locasale JW,Li L,Shats I,Li X
Fri Aug 07 00:00:00 EDT 2020
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
Nature communications
Guo L,Cui C,Wang J,Yuan J,Yang Q,Zhang P,Su W,Bao R,Ran J,Wu C
Thu Oct 01 00:00:00 EDT 2020
Wnt/β-catenin signaling regulates brain-derived neurotrophic factor release from spinal microglia to mediate HIV1 gp120-induced neuropathic pain.
Molecular pain
Zhou X,Tao L,Zhao M,Wu S,Obeng E,Wang D,Zhang W
Thu Jun 03 00:00:00 EDT 2021
miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells.
Oncotarget
Monteleone NJ,Lutz CS
Tue Jun 30 00:00:00 EDT 2020
Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis.
Diabetes
Tian N,Liu Q,Li Y,Tong L,Lu Y,Zhu Y,Zhang P,Chen H,Hu L,Meng J,Feng M,Li M,Zheng L,Li B,Xu T,Wu L,Tong X
Wed Jul 01 00:00:00 EDT 2020
Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth.
Cell reports
Rong B,Zhang Q,Wan J,Xing S,Dai R,Li Y,Cai J,Xie J,Song Y,Chen J,Zhang L,Yan G,Zhang W,Gao H,Han JJ,Qu Q,Ma H,Tian Y,Lan F
Tue Dec 22 00:00:00 EST 2020
PTPN2 regulates the activation of KRAS and plays a critical role in proliferation and survival of KRAS-driven cancer cells.
The Journal of biological chemistry
Huang Z,Liu M,Li D,Tan Y,Zhang R,Xia Z,Wang P,Jiao B,Liu P,Ren R
Fri Dec 25 00:00:00 EST 2020
KLF9-dependent ROS regulate melanoma progression in stage-specific manner.
Oncogene
Bagati A,Moparthy S,Fink EE,Bianchi-Smiraglia A,Yun DH,Kolesnikova M,Udartseva OO,Wolff DW,Roll MV,Lipchick BC,Han Z,Kozlova NI,Jowdy P,Berman AE,Box NF,Rodriguez C,Bshara W,Kandel ES,Soengas MS,Paragh G,Nikiforov MA
Wed May 01 00:00:00 EDT 2019
The histone deacetylase inhibitor LBH589 inhibits undifferentiated pleomorphic sarcoma growth via downregulation of FOS-like antigen 1.
Molecular carcinogenesis
Saitoh Y,Bureta C,Sasaki H,Nagano S,Maeda S,Furukawa T,Taniguchi N,Setoguchi T
Fri Feb 01 00:00:00 EST 2019
The histone deacetylase inhibitor LBH589 inhibits undifferentiated pleomorphic sarcoma growth via downregulation of FOS-like antigen 1.
Molecular carcinogenesis
Saitoh Y,Bureta C,Sasaki H,Nagano S,Maeda S,Furukawa T,Taniguchi N,Setoguchi T
Fri Feb 01 00:00:00 EST 2019
Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells.
Cell death & disease
Zhu ZC,Liu JW,Yang C,Li MJ,Wu RJ,Xiong ZQ
Mon Feb 11 00:00:00 EST 2019
Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Nature immunology
Melum E,Jiang X,Baker KD,Macedo MF,Fritsch J,Dowds CM,Wang J,Pharo A,Kaser A,Tan C,Pereira CS,Kelly SL,Duan J,Karlsen TH,Exley MA,Schütze S,Zajonc DM,Merrill AH,Schuchman EH,Zeissig S,Blumberg RS
Sun Dec 01 00:00:00 EST 2019
Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14.
Nutrients
Scheiber IF,Alarcon NO,Zhao N
Fri Jun 28 00:00:00 EDT 2019
Bombyx mori cypovirus encoded small peptide inhibits viral multiplication.
Developmental and comparative immunology
Hu X,Chen F,Zhu L,Yu L,Zhu M,Liang Z,Zhang X,Xue R,Cao G,Gong C
Mon Jul 01 00:00:00 EDT 2019
Neurotensin receptor 1 is a new therapeutic target for human undifferentiated pleomorphic sarcoma growth.
Molecular carcinogenesis
Tokumoto H,Setoguchi T,Saitoh Y,Sasaki H,Nagano S,Maeda S,Tanimoto A,Taniguchi N
Sun Dec 01 00:00:00 EST 2019
XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis.
Cell death & disease
Zhu ZC,Liu JW,Yang C,Zhao M,Xiong ZQ
Tue May 21 00:00:00 EDT 2019
miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer.
Scientific reports
Monteleone NJ,Moore AE,Iacona JR,Lutz CS,Dixon DA
Mon Apr 01 00:00:00 EDT 2019
Synergistic effect of arsenic trioxide, vismodegib and temozolomide on glioblastoma.
Oncology reports
Bureta C,Saitoh Y,Tokumoto H,Sasaki H,Maeda S,Nagano S,Komiya S,Taniguchi N,Setoguchi T
Sat Jun 01 00:00:00 EDT 2019
An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis.
Molecular cell
Mayank AK,Pandey V,Vashisht AA,Barshop WD,Rayatpisheh S,Sharma T,Haque T,Powers DN,Wohlschlegel JA
Thu Jul 25 00:00:00 EDT 2019
Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages.
Cell
Su S,Zhao J,Xing Y,Zhang X,Liu J,Ouyang Q,Chen J,Su F,Liu Q,Song E
Thu Oct 04 00:00:00 EDT 2018
Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages.
Cell
Su S,Zhao J,Xing Y,Zhang X,Liu J,Ouyang Q,Chen J,Su F,Liu Q,Song E
Thu Oct 04 00:00:00 EDT 2018
Triggering receptor expressed on myeloid cells 2 (TREM2) dependent microglial activation promotes cisplatin-induced peripheral neuropathy in mice.
Brain, behavior, and immunity
Hu LY,Zhou Y,Cui WQ,Hu XM,Du LX,Mi WL,Chu YX,Wu GC,Wang YQ,Mao-Ying QL
Thu Feb 01 00:00:00 EST 2018
Triggering receptor expressed on myeloid cells 2 (TREM2) dependent microglial activation promotes cisplatin-induced peripheral neuropathy in mice.
Brain, behavior, and immunity
Hu LY,Zhou Y,Cui WQ,Hu XM,Du LX,Mi WL,Chu YX,Wu GC,Wang YQ,Mao-Ying QL
Thu Feb 01 00:00:00 EST 2018
KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect.
Annals of neurology
Metz KA,Teng X,Coppens I,Lamb HM,Wagner BE,Rosenfeld JA,Chen X,Zhang Y,Kim HJ,Meadow ME,Wang TS,Haberlandt ED,Anderson GW,Leshinsky-Silver E,Bi W,Markello TC,Pratt M,Makhseed N,Garnica A,Danylchuk NR,Burrow TA,Jayakar P,McKnight D,Agadi S,Gbedawo H,Stanley C,Alber M,Prehl I,Peariso K,Ong MT,Mordekar SR,Parker MJ,Crooks D,Agrawal PB,Berry GT,Loddenkemper T,Yang Y,Maegawa GHB,Aouacheria A,Markle JG,Wohlschlegel JA,Hartman AL,Hardwick JM
Thu Nov 01 00:00:00 EDT 2018
KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect.
Annals of neurology
Metz KA,Teng X,Coppens I,Lamb HM,Wagner BE,Rosenfeld JA,Chen X,Zhang Y,Kim HJ,Meadow ME,Wang TS,Haberlandt ED,Anderson GW,Leshinsky-Silver E,Bi W,Markello TC,Pratt M,Makhseed N,Garnica A,Danylchuk NR,Burrow TA,Jayakar P,McKnight D,Agadi S,Gbedawo H,Stanley C,Alber M,Prehl I,Peariso K,Ong MT,Mordekar SR,Parker MJ,Crooks D,Agrawal PB,Berry GT,Loddenkemper T,Yang Y,Maegawa GHB,Aouacheria A,Markle JG,Wohlschlegel JA,Hartman AL,Hardwick JM
Thu Nov 01 00:00:00 EDT 2018
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
American journal of human genetics
Bozal-Basterra L,Martín-Ruíz I,Pirone L,Liang Y,Sigurðsson JO,Gonzalez-Santamarta M,Giordano I,Gabicagogeascoa E,de Luca A,Rodríguez JA,Wilkie AOM,Kohlhase J,Eastwood D,Yale C,Olsen JV,Rauchman M,Anderson KV,Sutherland JD,Barrio R
Thu Feb 01 00:00:00 EST 2018
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
American journal of human genetics
Bozal-Basterra L,Martín-Ruíz I,Pirone L,Liang Y,Sigurðsson JO,Gonzalez-Santamarta M,Giordano I,Gabicagogeascoa E,de Luca A,Rodríguez JA,Wilkie AOM,Kohlhase J,Eastwood D,Yale C,Olsen JV,Rauchman M,Anderson KV,Sutherland JD,Barrio R
Thu Feb 01 00:00:00 EST 2018
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Oncogene
Zhu ZC,Liu JW,Li K,Zheng J,Xiong ZQ
Tue May 01 00:00:00 EDT 2018
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Oncogene
Zhu ZC,Liu JW,Li K,Zheng J,Xiong ZQ
Tue May 01 00:00:00 EDT 2018
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.
The Journal of cell biology
Papadopoulos N,Lennartsson J,Heldin CH
Mon May 07 00:00:00 EDT 2018
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.
The Journal of cell biology
Papadopoulos N,Lennartsson J,Heldin CH
Mon May 07 00:00:00 EDT 2018
[6]-Gingerol enhances the radiosensitivity of gastric cancer via G2/M phase arrest and apoptosis induction.
Oncology reports
Luo Y,Chen X,Luo L,Zhang Q,Gao C,Zhuang X,Yuan S,Qiao T
Tue May 01 00:00:00 EDT 2018
[6]-Gingerol enhances the radiosensitivity of gastric cancer via G2/M phase arrest and apoptosis induction.
Oncology reports
Luo Y,Chen X,Luo L,Zhang Q,Gao C,Zhuang X,Yuan S,Qiao T
Tue May 01 00:00:00 EDT 2018
Identifying the SUMO1 modification of FAM122A leading to the degradation of PP2A-Cα by ubiquitin-proteasome system.
Biochemical and biophysical research communications
Fan F,Zhao J,Liu Y,Zhao H,Weng L,Li Q,Chen G,Xu Y
Thu Jun 07 00:00:00 EDT 2018
Identifying the SUMO1 modification of FAM122A leading to the degradation of PP2A-Cα by ubiquitin-proteasome system.
Biochemical and biophysical research communications
Fan F,Zhao J,Liu Y,Zhao H,Weng L,Li Q,Chen G,Xu Y
Thu Jun 07 00:00:00 EDT 2018
Construction of a GLI3 compound heterozygous knockout human embryonic stem cell line WAe001-A-20 by CRISPR/Cas9 editing.
Stem cell research
Wei R,Yuan F,Wu Y,Liu Y,You K,Yang Z,Chen Y,Getachew A,Wang N,Xu Y,Zhuang Y,Yang F,Li YX
Mon Oct 01 00:00:00 EDT 2018
Construction of a GLI3 compound heterozygous knockout human embryonic stem cell line WAe001-A-20 by CRISPR/Cas9 editing.
Stem cell research
Wei R,Yuan F,Wu Y,Liu Y,You K,Yang Z,Chen Y,Getachew A,Wang N,Xu Y,Zhuang Y,Yang F,Li YX
Mon Oct 01 00:00:00 EDT 2018
Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals.
Immunity
Qiu Y,Xu Y,Zhang Y,Zhou H,Deng YQ,Li XF,Miao M,Zhang Q,Zhong B,Hu Y,Zhang FC,Wu L,Qin CF,Zhou X
Tue Oct 16 00:00:00 EDT 2018
miR-146a suppresses 5-lipoxygenase activating protein (FLAP) expression and Leukotriene B4 production in lung cancer cells.
Oncotarget
Iacona JR,Monteleone NJ,Lutz CS
Fri Jun 01 00:00:00 EDT 2018
miR-146a suppresses 5-lipoxygenase activating protein (FLAP) expression and Leukotriene B4 production in lung cancer cells.
Oncotarget
Iacona JR,Monteleone NJ,Lutz CS
Fri Jun 01 00:00:00 EDT 2018
The Natural Compound Myricetin Effectively Represses the Malignant Progression of Prostate Cancer by Inhibiting PIM1 and Disrupting the PIM1/CXCR4 Interaction.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Ye C,Zhang C,Huang H,Yang B,Xiao G,Kong D,Tian Q,Song Q,Song Y,Tan H,Wang Y,Zhou T,Zi X,Sun Y
Fri Sep 14 00:00:00 EDT 2018
Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals.
Immunity
Qiu Y,Xu Y,Zhang Y,Zhou H,Deng YQ,Li XF,Miao M,Zhang Q,Zhong B,Hu Y,Zhang FC,Wu L,Qin CF,Zhou X
Tue Jun 20 00:00:00 EDT 2017
Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals.
Immunity
Qiu Y,Xu Y,Zhang Y,Zhou H,Deng YQ,Li XF,Miao M,Zhang Q,Zhong B,Hu Y,Zhang FC,Wu L,Qin CF,Zhou X
Tue Jun 20 00:00:00 EDT 2017
The Polyphenol Oleuropein Aglycone Modulates the PARP1-SIRT1 Interplay: An In Vitro and In Vivo Study.
Journal of Alzheimer's disease : JAD
Luccarini I,Pantano D,Nardiello P,Cavone L,Lapucci A,Miceli C,Nediani C,Berti A,Stefani M,Casamenti F
Tue Sep 06 00:00:00 EDT 2016
The Polyphenol Oleuropein Aglycone Modulates the PARP1-SIRT1 Interplay: An In Vitro and In Vivo Study.
Journal of Alzheimer's disease : JAD
Luccarini I,Pantano D,Nardiello P,Cavone L,Lapucci A,Miceli C,Nediani C,Berti A,Stefani M,Casamenti F
Tue Sep 06 00:00:00 EDT 2016
