Product References
Microtubule organizing centers regulate spindle positioning in mouse oocytes.
Developmental cell
Londoño-Vásquez D,Rodriguez-Lukey K,Behura SK,Balboula AZ
322588 was used in Immunocytochemistry-immunofluorescence to provide a model for asymmetric cell division, complementing the current F-actin-based models, and implicate mcMTOCs as a major player in regulating spindle positioning.
Mon Jan 24 00:00:00 EST 2022
Miro1 regulates mitochondrial homeostasis and meiotic resumption of mouse oocyte.
Journal of cellular physiology
Xue Y,Meng TG,Ouyang YC,Liu SL,Guo JN,Wang ZB,Schatten H,Song CY,Guo XP,Sun QY
322588 was used in Immunocytochemistry to evaluate whether Miro1 regulates mouse oocyte maturation by altering mitochondrial homeostasis.
Thu Dec 01 00:00:00 EST 2022
Using ZINC08918027 inhibitor to determine Aurora kinase-chromosomal passenger complex isoforms in mouse oocytes.
BMC research notes
Kratka C,Drutovic D,Blengini CS,Schindler K
322588 was used in Immunohistochemistry to examine the utility of ZINC08918027, an inhibitor that prevents the interaction between AURKB and INCENP in mitotic cells, in disrupting chromosomal passenger complex function in mouse oocytes.
Mon Mar 07 00:00:00 EST 2022
Toxic effects of AZD1208 on mouse oocytes and its possible mechanisms.
Journal of cellular physiology
Yan FZ,Ouyang YC,Meng TG,Zhang HY,Yue W,Zhang XR,Xue Y,Wang ZB,Sun QY
322588 was used in Immunocytochemistry-immunofluorescence to suggest that AZD1208 treatment influences oocyte meiotic progression by causing mitochondrial dysfunctions and subsequent delayed spindle assembly.
Thu Sep 01 00:00:00 EDT 2022
Miro1 depletion disrupts spatial distribution of mitochondria and leads to oocyte maturation defects.
Frontiers in cell and developmental biology
Lee IW,Adhikari D,Carroll J
322588 was used in Immunocytochemistry-immunofluorescence to demonstrate MIRO1 acts as a mitochondrial adaptor, setting mitochondrial distribution in oocytes and early embryos, and disrupting this process compromises in vitro oocyte maturation and embryo development.
Fri Nov 04 00:00:00 EDT 2022
Transient inhibition of CDK2 activity prevents oocyte meiosis I completion and egg activation in mouse.
Journal of cellular physiology
Li J,Chang HY,Yi ZY,Zhang CH,Sun QY,Qian WP
322588 was used in Immunocytochemistry to demonstrate that CDK2 kinase activity is required for proper dynamics of spindle and chromosomes, whose disturbance induces the continuous SAC activation and subsequent inactivation of APC/C activity in oocyte meiosis.
Tue Nov 01 00:00:00 EDT 2022
Age-dependent integrity of the meiotic spindle assembly checkpoint in females requires Aurora kinase B.
Aging cell
Blengini CS,Nguyen AL,Aboelenain M,Schindler K
322588 was used in Immunocytochemistry, Immunohistochemistry to demonstrate a novel function for AURKB in preserving the female reproductive lifespan possibly by protecting oocytes from oxidative stress.
Mon Nov 01 00:00:00 EDT 2021
Cell Division Cycle 5-Like Regulates Metaphase-to-Anaphase Transition in Meiotic Oocyte.
Frontiers in cell and developmental biology
Zhang HY,Li J,Ouyang YC,Meng TG,Zhang CH,Yue W,Sun QY,Qian WP
322588 was used in Immunocytochemistry-immunofluorescence to reveal a novel role for Cdc5L in regulating mouse oocyte meiotic progression by interacting with securin.
Tue Jul 20 00:00:00 EDT 2021
Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle.
The Journal of general physiology
Coleman AK,Joca HC,Shi G,Lederer WJ,Ward CW
322588 was used in Western Blot to add to growing evidence that microtubules contribute to the mechanobiology of striated muscle in health and disease.
Mon Jul 05 00:00:00 EDT 2021
Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle.
The Journal of general physiology
Coleman AK,Joca HC,Shi G,Lederer WJ,Ward CW
322588 was used in Western Blot to add to growing evidence that microtubules contribute to the mechanobiology of striated muscle in health and disease.
Mon Jul 05 00:00:00 EDT 2021
Aurora kinase A is essential for meiosis in mouse oocytes.
PLoS genetics
Blengini CS,Ibrahimian P,Vaskovicova M,Drutovic D,Solc P,Schindler K
322588 was used in Immunocytochemistry to conclude that AURKA has multiple functions essential to completing MI that are distinct from AURKB and AURKC.
Thu Apr 01 00:00:00 EDT 2021
Knockout of mouse receptor accessory protein 6 leads to sperm function and morphology defects†.
Biology of reproduction
Devlin DJ,Agrawal Zaneveld S,Nozawa K,Han X,Moye AR,Liang Q,Harnish JM,Matzuk MM,Chen R
322588 was used in Immunohistochemistry to reveal an important role for REEP6 in sperm motility and morphology and is the first reported function for a REEP protein in reproductive processes.
Tue May 26 00:00:00 EDT 2020
Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†.
Biology of reproduction
Devlin DJ,Nozawa K,Ikawa M,Matzuk MM
322588 was used in Immunocytochemistry-immunoflourescence to study the role of family with sequence similarity 170 (FAM170) members A and B in male mice fertility.
Tue Aug 04 00:00:00 EDT 2020
NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.
Cell reports
Nourreddine S,Lavoie G,Paradis J,Ben El Kadhi K,Méant A,Aubert L,Grondin B,Gendron P,Chabot B,Bouvier M,Carreno S,Roux PP
322588 was used in Immunocytochemistry-immunoflourescence to indicate that the NF45-NF90 complex plays essential roles in mitosis by competing with the SMD machinery for a common set of mRNAs.
Tue May 19 00:00:00 EDT 2020
RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.
Molecular cell
Liccardi G,Ramos Garcia L,Tenev T,Annibaldi A,Legrand AJ,Robertson D,Feltham R,Anderton H,Darding M,Peltzer N,Dannappel M,Schünke H,Fava LL,Haschka MD,Glatter T,Nesvizhskii A,Schmidt A,Harris PA,Bertin J,Gough PJ,Villunger A,Silke J,Pasparakis M,Bianchi K,Meier P
322588 was used in Immunocytochemistry-immunoflourescence to assess the role of ripoptosome-mediated regulation of Polo-like kinase 1 in faithful chromosome segregation during mitosis.
Thu Feb 07 00:00:00 EST 2019
LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency.
PLoS pathogens
De Leo A,Deng Z,Vladimirova O,Chen HS,Dheekollu J,Calderon A,Myers KA,Hayden J,Keeney F,Kaufer BB,Yuan Y,Robertson E,Lieberman PM
322588 was used in Immunocytochemistry-immunoflourescence to investigate the molecular basis for the formation of functional, higher-ordered macro-molecular domains.
Tue Jan 01 00:00:00 EST 2019
The cyclin B2/CDK1 complex inhibits separase activity in mouse oocyte meiosis I.
Development (Cambridge, England)
Li J,Ouyang YC,Zhang CH,Qian WP,Sun QY
322588 was used in Immunocytochemistry-Immunofluorescence to study the interaction between cyclin B2/CDK1 and separase in mouse oocytes.
Mon Dec 02 00:00:00 EST 2019
Loss of the E2 SUMO-conjugating enzyme Ube2i in oocytes during ovarian folliculogenesis causes infertility in mice.
Development (Cambridge, England)
Rodriguez A,Briley SM,Patton BK,Tripurani SK,Rajapakshe K,Coarfa C,Rajkovic A,Andrieux A,Dejean A,Pangas SA
322588 was used in Immunocytochemistry-immunoflourescence to show that SUMOylation is required in the mammalian oocyte during folliculogenesis for both oocyte development and communication with ovarian somatic cells.
Mon Dec 02 00:00:00 EST 2019
Cigarette and ENDS preparations differentially regulate ion channels and mucociliary clearance in primary normal human bronchial 3D cultures.
American journal of physiology. Lung cellular and molecular physiology
Rayner RE,Makena P,Prasad GL,Cormet-Boyaka E
322588 was used in Immunohistochemistry to compare the effects of acute exposure of primary normal human bronchial epithelial (NHBE) 3D cultures at air-liquid interface to combustible cigarette and ENDS preparations on mucociliary function, including ion channel function, ciliary beat frequency (CBF), and airway surface liquid (ASL) height.
Thu Aug 01 00:00:00 EDT 2019
Optimization of Normal Human Bronchial Epithelial (NHBE) Cell 3D Cultures for in vitro Lung Model Studies.
Scientific reports
Rayner RE,Makena P,Prasad GL,Cormet-Boyaka E
322588 was used in Immunohistochemistry-immunofluorescence to evaluate the ability to expand primary normal human bronchial epithelial cells in different culture conditions while maintaining their 3D culture characteristics.
Thu Jan 24 00:00:00 EST 2019
A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma.
Cancers
White CL,Jayasekara WSN,Picard D,Chen J,Watkins DN,Cain JE,Remke M,Gough DJ
322588 was used in Immunohistochemistry to identify a sex-specific role for the transcription factor Signal Transducer and Activator of Transcription 3 in the Sonic Hedgehog medulloblastoma subgroup.
Fri Nov 01 00:00:00 EDT 2019
A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis.
Nature communications
Kim YH,Choi J,Yang MJ,Hong SP,Lee CK,Kubota Y,Lim DS,Koh GY
322588 was used in Immunocytochemistry-Immunofluorescence to delineate a crucial coupling between extracellular hypoxia and an intracellular reactive oxygen species-MST1-FOXO1 cascade in establishing endothelial tip cell polarity during sprouting angiogenesis.
Tue Feb 19 00:00:00 EST 2019
Rainbow-Seq: Combining Cell Lineage Tracing with Single-Cell RNA Sequencing in Preimplantation Embryos.
iScience
Biase FH,Wu Q,Calandrelli R,Rivas-Astroza M,Zhou S,Chen Z,Zhong S
322588 was used in Immunocytochemistry to develop and present Rainbow-seq, a method that combines cell division lineage tracing with single-cell RNA sequencing in mouse embryos.
Fri Sep 28 00:00:00 EDT 2018
Immunofluorescence Technique to Detect Subcellular Structures Critical to Oocyte Maturation.
Methods in molecular biology (Clifton, N.J.)
Blengini CS,Schindler K
322588 was used in Immunocytochemistry-immunofluorescence to successfully apply immunofluoresence technique to visualise anti-centromeric antigen (ACA), anti-Aurora kinase A (AURKA) and anti-alpha and gamma-tubulin antibodies for mouse oocyte studies.
Fri Mar 22 00:00:00 EDT 2019
The effects of antiviral treatment on breast cancer cell line.
Infectious agents and cancer
Shaimerdenova M,Karapina O,Mektepbayeva D,Alibek K,Akilbekova D
Thu Oct 01 00:00:00 EDT 2020
The effects of antiviral treatment on breast cancer cell line.
Infectious agents and cancer
Shaimerdenova M,Karapina O,Mektepbayeva D,Alibek K,Akilbekova D
Thu Oct 01 00:00:00 EDT 2020
Automated classification and characterization of the mitotic spindle following knockdown of a mitosis-related protein.
BMC bioinformatics
Khushi M,Dean IM,Teber ET,Chircop M,Arthur JW,Flores-Rodriguez N
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Thu Dec 28 00:00:00 EST 2017
Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes.
Journal of cell science
Balboula AZ,Nguyen AL,Gentilello AS,Quartuccio SM,Drutovic D,Solc P,Schindler K
322588 was used in immunocytochemistry to determine the role of haspin in bipolar spindle assembly
Sat Oct 01 00:00:00 EDT 2016
Monomethyl Auristatin E Phosphate Inhibits Human Prostate Cancer Growth.
The Prostate
Cunningham D,Parajuli KR,Zhang C,Wang G,Mei J,Zhang Q,Liu S,You Z
322588 was used in immunocytochemistry to research inhibition of human prostate cancer growth by monomethyl auristatin e phosphate
Tue Nov 01 00:00:00 EDT 2016
Monomethyl Auristatin E Phosphate Inhibits Human Prostate Cancer Growth.
The Prostate
Cunningham D,Parajuli KR,Zhang C,Wang G,Mei J,Zhang Q,Liu S,You Z
322588 was used in immunocytochemistry to research inhibition of human prostate cancer growth by monomethyl auristatin e phosphate
Tue Nov 01 00:00:00 EDT 2016
Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture.
Nature communications
Stritt S,Nurden P,Favier R,Favier M,Ferioli S,Gotru SK,van Eeuwijk JM,Schulze H,Nurden AT,Lambert MP,Turro E,Burger-Stritt S,Matsushita M,Mittermeier L,Ballerini P,Zierler S,Laffan MA,Chubanov V,Gudermann T,Nieswandt B,Braun A
322588 was used in immunocytochemistry to determine the role of TRPM7 channel function defects and how they deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture
Tue Mar 29 00:00:00 EDT 2016
Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture.
Nature communications
Stritt S,Nurden P,Favier R,Favier M,Ferioli S,Gotru SK,van Eeuwijk JM,Schulze H,Nurden AT,Lambert MP,Turro E,Burger-Stritt S,Matsushita M,Mittermeier L,Ballerini P,Zierler S,Laffan MA,Chubanov V,Gudermann T,Nieswandt B,Braun A
322588 was used in immunocytochemistry to determine the role of TRPM7 channel function defects and how they deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture
Tue Mar 29 00:00:00 EDT 2016
The Clathrin-dependent Spindle Proteome.
Molecular & cellular proteomics : MCP
Rao SR,Flores-Rodriguez N,Page SL,Wong C,Robinson PJ,Chircop M
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunocytochemistry
Mon Aug 01 00:00:00 EDT 2016
Open-source image reconstruction of super-resolution structured illumination microscopy data in ImageJ.
Nature communications
Müller M,Mönkemöller V,Hennig S,Hübner W,Huser T
322588 was used in immunocytochemistry to determine characteristics of ImageJ through open-source image reconstruction of super-resolution structured illumination microscopy data
Mon Mar 21 00:00:00 EDT 2016
Recovery of altered neuromuscular junction morphology and muscle function in mdx mice after injury.
Cellular and molecular life sciences : CMLS
Pratt SJP,Shah SB,Ward CW,Kerr JP,Stains JP,Lovering RM
322588 was used in immunohistochemistry to investigate mdx mice after injury and recovery of altered neuromuscular junction morphology and muscle function
Thu Jan 01 00:00:00 EST 2015
RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse.
Biology of reproduction
Balboula AZ,Stein P,Schultz RM,Schindler K
322588 was used in immunocytochemistry to assess the role of RBBP4 during meiosis
Wed Apr 01 00:00:00 EDT 2015
Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes.
Journal of cell science
Nguyen AL,Gentilello AS,Balboula AZ,Shrivastava V,Ohring J,Schindler K
322588 was used in Immunofluorescence to implicate haspin as a regulator of the CPC and chromosome segregation during MI, while highlighting important differences in how chromosome segregation is regulated between MI and mitosis.
Mon Dec 01 00:00:00 EST 2014
Knockdown of RBBP7 unveils a requirement of histone deacetylation for CPC function in mouse oocytes.
Cell cycle (Georgetown, Tex.)
Balboula AZ,Stein P,Schultz RM,Schindler K
322588 was used in Immunocytochemistry-immunoflourescence to identify RBBP7 as a novel regulator of histone deacetylation during oocyte maturation and provide evidence that such deacetylation is required for proper chromosome segregation.
Thu Apr 16 00:00:00 EDT 2015
Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect.
Nature communications
Bender M,Stritt S,Nurden P,van Eeuwijk JM,Zieger B,Kentouche K,Schulze H,Morbach H,Stegner D,Heinze KG,Dütting S,Gupta S,Witke W,Falet H,Fischer A,Hartwig JH,Nieswandt B
322588 was used in Immunocytochemistry-immunofluorescence to identify Profilin1 as a regulator of microtubule organisation and identify the mechanism underlying the platelet formation defect in Wiskott-Aldrich syndrome.
Thu Sep 04 00:00:00 EDT 2014
Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes.
PLoS genetics
Balboula AZ,Schindler K
322588 was used in immunocytochemistry to determine how disruption of aurora C kinase reveals functions of aurora B kinase during meiosis in mouse oocytes
Sat Feb 01 00:00:00 EST 2014
CLP36 is a negative regulator of glycoprotein VI signaling in platelets.
Circulation research
Gupta S,Braun A,Morowski M,Premsler T,Bender M,Nagy Z,Sickmann A,Hermanns HM,Bösl M,Nieswandt B
322588 was used in Immunofluorescecne to examine the role of CLP36 in platelet physiology both in vitro and in vivo.
Fri Nov 09 00:00:00 EST 2012