Product References
Cytochalasin D restores nuclear size acting on F-actin and IZUMO1 localization in low-quality spermatozoa.
International journal of biological sciences
Martinez G,Cappetta D,Telesca M,Urbanek K,Castaldo G,Dhellemmes M,Mele VG,Chioccarelli T,Porreca V,Barbotin AL,Boursier A,Guillou F,Coutton C,Brouillet S,De Angelis A,Berrino L,Pierantoni R,Cobellis G,Chianese R,Manfrevola F
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Tue May 09 00:00:00 EDT 2023
Expression of HSPA14 in patients with acute HIV-1 infection and its effect on HIV-1 replication.
Frontiers in immunology
Bi M,Kang W,Sun Y
PA1-16889 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to find that the expression level of HSPA14 is higher in peripheral blood CD4+T cells of untreated acute HIV infection patients with low viral load.
Tue Feb 28 00:00:00 EST 2023
Maternal Methyl-Enriched Diet Increases DNMT1, HCN1, and TH Gene Expression and Suppresses Absence Seizures and Comorbid Depression in Offspring of WAG/Rij Rats.
Diagnostics (Basel, Switzerland)
Sarkisova KY,Fedosova EA,Shatskova AB,Rudenok MM,Stanishevskaya VA,Slominsky PA
PA1-16889 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to indicate that maternal methyl-enriched diet (MED) can suppress the genetic absence epilepsy and comorbid depression in offspring of WAG/Rij Rats.
Sat Jan 21 00:00:00 EST 2023
EML1 is essential for retinal photoreceptor migration and survival.
Scientific reports
Poria D,Sun C,Santeford A,Kielar M,Apte RS,Kisselev OG,Chen S,Kefalov VJ
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Mon Feb 21 00:00:00 EST 2022
Constricted migration is associated with stable 3D genome structure differences in cancer cells.
EMBO reports
Golloshi R,Playter C,Freeman TF,Das P,Raines TI,Garretson JH,Thurston D,McCord RP
PA1-16889 was used in Western Blotting to suggest that consistent types of chromosome structure changes are induced or selected by passage through constrictions and that these may epigenetically encode stable differences in gene expression and cellular migration phenotype.
Thu Oct 06 00:00:00 EDT 2022
Transplantation of Human Glial Progenitors to Immunodeficient Neonatal Mice with Amyotrophic Lateral Sclerosis (SOD1/rag2).
Antioxidants (Basel, Switzerland)
Stanaszek L,Rogujski P,Drela K,Fiedorowicz M,Walczak P,Lukomska B,Janowski M
PA1-16889 was used in Western Blotting to develop an immunodeficient model of ALS (double mutant SOD1/rag2), and, in this study, we tested the strategy previously used in dysmyelinated mice of intraventricular transplantation of hGRPs to immunodeficient mice.
Thu May 26 00:00:00 EDT 2022
Optimization of small extracellular vesicle isolation from expressed prostatic secretions in urine for in-depth proteomic analysis.
Journal of extracellular vesicles
Correll VL,Otto JJ,Risi CM,Main BP,Boutros PC,Kislinger T,Galkin VE,Nyalwidhe JO,Semmes OJ,Yang L
PA1-16889 was used in Western Blotting to provide a promising strategy for global proteomic analyses of urinary EVs.
Tue Feb 01 00:00:00 EST 2022
Trade-offs between male fertility reduction and selected growth factors or the klotho response in a lipopolysaccharide-dependent mouse model.
Toxicological research
Solek P,Mytych J,Sujkowska E,Grzegorczyk M,Jasiewicz P,Sowa-Kucma M,Stachowicz K,Koziorowski M,Tabecka-Lonczynska A
PA1-16889 was used in Western Blotting to suggest that the tested ALS and LPS can contribute to a reduction of male fertility, but NS-398, IMI, and IMI+NS-398 may also act as stimulants after LPS.
Fri Apr 01 00:00:00 EDT 2022
Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits.
PloS one
Kolesnikov AV,Lobysheva E,Gnana-Prakasam JP,Kefalov VJ,Kisselev OG
PA1-16889 was used in Western Blotting to conclude that, while farnesylated Gγ subunits are functionally active and largely interchangeable in supporting rod phototransduction, replacement of retina-specific Gγ isoforms by the ubiquitous Gγ11 affects the ability of rods to adapt to background light.
Wed Aug 10 00:00:00 EDT 2022
Temporal and brain region-specific elevations of soluble Amyloid-β40-42 in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.
Aging cell
Tallino S,Winslow W,Bartholomew SK,Velazquez R
PA1-16889 was used in Western Blotting to show that trisomic mice accumulate soluble Aβ40-42 in the basal forebrain, frontal cortex, hippocampus, and cerebellum in an age-specific manner, with elevation in the frontal cortex and hippocampus as early as 4 months of age.
Fri Apr 01 00:00:00 EDT 2022
Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model.
Scientific reports
Kumar MJV,Shah D,Giridharan M,Yadav N,Manjithaya R,Clement JP
PA1-16889 was used in Western Blotting to show that basal autophagy is not altered in R6/2 mice, whilst being functional at a steady-state level in neurons.
Fri Jan 08 00:00:00 EST 2021
Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model.
Scientific reports
Kumar MJV,Shah D,Giridharan M,Yadav N,Manjithaya R,Clement JP
PA1-16889 was used in Western Blotting to show that basal autophagy is not altered in R6/2 mice, whilst being functional at a steady-state level in neurons.
Fri Jan 08 00:00:00 EST 2021
IntelliCage Automated Behavioral Phenotyping Reveals Behavior Deficits in the 3xTg-AD Mouse Model of Alzheimer's Disease Associated With Brain Weight.
Frontiers in aging neuroscience
Winslow W,McDonough I,Tallino S,Decker A,Vural AS,Velazquez R
PA1-16889 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to examine d the behavioral performance of 3xTg-AD mice in the IntelliCage o study mechanisms of pathogenesis and connect these mechanisms with cognitive decline.
Thu Apr 14 00:00:00 EDT 2022
Structure-based virtual screening identifies an 8-hydroxyquinoline as a small molecule GLI1 inhibitor.
Molecular therapy oncolytics
Dash RC,Wen J,Zaino AM,Morel SR,Chau LQ,Wechsler-Reya RJ,Hadden MK
PA1-16889 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to suggest that binding of 1 to GLI1 does not prevent GLI1/DNA binding nor disrupt the GLI1/DNA complex, but rather, it induces specific conformational changes in the overall complex that prevent proper GLI function.
Fri Mar 26 00:00:00 EDT 2021
An acidic polysaccharide (AGC3) isolated from North American ginseng (Panax quinquefolius) suspension culture as a potential immunomodulatory nutraceutical.
Current research in food science
Ghosh R,Bryant DL,Arivett BA,Smith SA,Altman E,Kline PC,Farone AL
PA1-16889 was used in Western Blotting to suggest that AGC3, an acidic polysaccharide fraction isolated from Panax quinquefolius suspension culture, has the potential to be used as an immunostimulatory nutraceutical.
Sun Nov 01 00:00:00 EDT 2020
An acidic polysaccharide (AGC3) isolated from North American ginseng (Panax quinquefolius) suspension culture as a potential immunomodulatory nutraceutical.
Current research in food science
Ghosh R,Bryant DL,Arivett BA,Smith SA,Altman E,Kline PC,Farone AL
PA1-16889 was used in Western Blotting to suggest that AGC3, an acidic polysaccharide fraction isolated from Panax quinquefolius suspension culture, has the potential to be used as an immunostimulatory nutraceutical.
Sun Nov 01 00:00:00 EDT 2020
Dl-3-n-Butylphthalide promotes neovascularization and neurological recovery in a rat model of intracerebral hemorrhage.
BMC neuroscience
Tu E,Chen Q,Tan L,Wang Y
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Fri May 29 00:00:00 EDT 2020
Dl-3-n-Butylphthalide promotes neovascularization and neurological recovery in a rat model of intracerebral hemorrhage.
BMC neuroscience
Tu E,Chen Q,Tan L,Wang Y
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Fri May 29 00:00:00 EDT 2020
Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes.
Cells
Mytych J,Sołek P,Będzińska A,Rusinek K,Warzybok A,Tabęcka-Łonczyńska A,Koziorowski M
PA1-16889 was used in Western Blotting to provide evidence of klotho involvement in the crosstalk on the line ER-Golgi, which may, in turn, affect activation of SASP.
Tue Jan 21 00:00:00 EST 2020
Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes.
Cells
Mytych J,Sołek P,Będzińska A,Rusinek K,Warzybok A,Tabęcka-Łonczyńska A,Koziorowski M
PA1-16889 was used in Western Blotting to provide evidence of klotho involvement in the crosstalk on the line ER-Golgi, which may, in turn, affect activation of SASP.
Tue Jan 21 00:00:00 EST 2020
Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma.
Nature communications
Yang Y,Luo M,Zhang K,Zhang J,Gao T,Connell DO,Yao F,Mu C,Cai B,Shang Y,Chen W
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Thu Jan 23 00:00:00 EST 2020
ECRG4 Represses Cell Proliferation and Invasiveness via NFIC/OGN/NF-κB Signaling Pathway in Bladder Cancer.
Frontiers in genetics
Liang X,Gao J,Wang Q,Hou S,Wu C
PA1-16889 was used in Western Blotting to provide evidence that both ECRG4 and OGN function as tumor repressors and that overexpression of ECRG4 inhibits the NF-κB signaling pathway by promoting NFIC/OGN signaling in BCa cells.
Mon Sep 28 00:00:00 EDT 2020
Radiation-induced DNA damage and repair effects on 3D genome organization.
Nature communications
Sanders JT,Freeman TF,Xu Y,Golloshi R,Stallard MA,Hill AM,San Martin R,Balajee AS,McCord RP
PA1-16889 was used in Western Blotting to investigate the impact of DNA damage response and repair on genome folding in wild type and ATM patient cells.
Wed Dec 02 00:00:00 EST 2020
Neuronal life or death linked to depression treatment: the interplay between drugs and their stress-related outcomes relate to single or combined drug therapies.
Apoptosis : an international journal on programmed cell death
Solek P,Koszla O,Mytych J,Badura J,Chelminiak Z,Cuprys M,Fraczek J,Tabecka-Lonczynska A,Koziorowski M
PA1-16889 was used in Western Blot to study the mechanisms of action of single antidepressants and their combinations.
Tue Oct 01 00:00:00 EDT 2019
YY1 cooperates with TFEB to regulate autophagy and lysosomal biogenesis in melanoma.
Molecular carcinogenesis
Du J,Ren W,Yao F,Wang H,Zhang K,Luo M,Shang Y,O'Connell D,Bei Z,Wang H,Xiong R,Yang Y
PA1-16889 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to identify YY1 as a novel cotranscription factor of TFEB in regulating autophagy and lysosomal functions and suggest YY1 could be a therapeutic target in cancer treatment.
Fri Nov 01 00:00:00 EDT 2019
YY1 cooperates with TFEB to regulate autophagy and lysosomal biogenesis in melanoma.
Molecular carcinogenesis
Du J,Ren W,Yao F,Wang H,Zhang K,Luo M,Shang Y,O'Connell D,Bei Z,Wang H,Xiong R,Yang Y
PA1-16889 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to identify YY1 as a novel cotranscription factor of TFEB in regulating autophagy and lysosomal functions and suggest YY1 could be a therapeutic target in cancer treatment.
Fri Nov 01 00:00:00 EDT 2019
Circulating Microparticles Are Elevated in Treated HIV -1 Infection and Are Deleterious to Endothelial Cell Function.
Journal of the American Heart Association
Hijmans JG,Stockelman KA,Garcia V,Levy MV,Brewster LM,Bammert TD,Greiner JJ,Stauffer BL,Connick E,DeSouza CA
PA1-16889 was used in Western Blotting and Immunoprecptiation to conclude circulating microparticles may contribute to the vascular risk associated with HIV -1 infection.
Tue Feb 19 00:00:00 EST 2019
Circulating Microparticles Are Elevated in Treated HIV -1 Infection and Are Deleterious to Endothelial Cell Function.
Journal of the American Heart Association
Hijmans JG,Stockelman KA,Garcia V,Levy MV,Brewster LM,Bammert TD,Greiner JJ,Stauffer BL,Connick E,DeSouza CA
PA1-16889 was used in Western Blotting and Immunoprecptiation to conclude circulating microparticles may contribute to the vascular risk associated with HIV -1 infection.
Tue Feb 19 00:00:00 EST 2019
Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells.
Cellular and molecular life sciences : CMLS
Driedonks TAP,van der Grein SG,Ariyurek Y,Buermans HPJ,Jekel H,Chow FWN,Wauben MHM,Buck AH,'t Hoen PAC,Nolte-'t Hoen ENM
PA1-16889 was used in Western Blotting to investigate whether immune-activating or -suppressing stimuli imposed on primary dendritic cells affected the release of various small non-coding RNAs via extracellular vesicles.
Mon Oct 01 00:00:00 EDT 2018
Role of TGF-β1/miR-382-5p/SOD2 axis in the induction of oxidative stress in CD34+ cells from primary myelofibrosis.
Molecular oncology
Rossi C,Zini R,Rontauroli S,Ruberti S,Prudente Z,Barbieri G,Bianchi E,Salati S,Genovese E,Bartalucci N,Guglielmelli P,Tagliafico E,Rosti V,Barosi G,Vannucchi AM,Manfredini R
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Sat Dec 01 00:00:00 EST 2018
C-reactive protein expression in adipose tissue of children with acute appendicitis.
Pediatric research
de Dios O,Gavela-Pérez T,Aguado-Roncero P,Pérez-Tejerizo G,Ricote M,González N,Garcés C,Soriano-Guillén L
PA1-16889 was used in Western Blotting to gain insights into the role of visceral adipose tissue as a source of C-reactive protein (CRP) in acute inflammation and to explore the potential relationship of CRP expression with the severity of appendicitis.
Mon Oct 01 00:00:00 EDT 2018
Melatonin receptors subtypes (MT1 and MT2) in the uterus masculinus of mature male european bison. Biological and seasonal reproductive role.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Tabecka-Lonczynska A,Mytych J,Solek P,Kulpa-Greszta M,Koziorowski M
PA1-16889 was used in Dot blot to evaluate the expression of mRNA and protein synthesis for both melatonin receptors in the tissues of uterus masculinus in November and December in European bison.
Thu Feb 01 00:00:00 EST 2018
Protective role of klotho protein on epithelial cells upon co-culture with activated or senescent monocytes.
Experimental cell research
Mytych J,Wos I,Solek P,Koziorowski M
PA116889 was used in western blot to show that ROS-induced DNA damage reduces metabolic activity, inhibits proliferation, and induces cell cycle arrest followed by activation of p16-, p21-, and p27- mediated DNA damage response pathways, premature senescence, and apoptosis induction
Sun Jan 15 00:00:00 EST 2017
Long-term culture with lipopolysaccharide induces dose-dependent cytostatic and cytotoxic effects in THP-1 monocytes.
Toxicology in vitro : an international journal published in association with BIBRA
Mytych J,Romerowicz-Misielak M,Koziorowski M
PA116889 was used in western blot to report the effects of long-term lipopolysaccharide exposure on monocytes
Tue Aug 01 00:00:00 EDT 2017
Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells.
Oncotarget
Salati S,Salvestrini V,Carretta C,Genovese E,Rontauroli S,Zini R,Rossi C,Ruberti S,Bianchi E,Barbieri G,Curti A,Castagnetti F,Gugliotta G,Rosti G,Bergamaschi M,Tafuri A,Tagliafico E,Lemoli R,Manfredini R
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Tue Jul 25 00:00:00 EDT 2017
miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6.
Oncotarget
Rontauroli S,Norfo R,Pennucci V,Zini R,Ruberti S,Bianchi E,Salati S,Prudente Z,Rossi C,Rosti V,Guglielmelli P,Barosi G,Vannucchi A,Tagliafico E,Manfredini R
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Tue Mar 28 00:00:00 EDT 2017
Role of miR-34a-5p in Hematopoietic Progenitor Cells Proliferation and Fate Decision: Novel Insights into the Pathogenesis of Primary Myelofibrosis.
International journal of molecular sciences
Bianchi E,Ruberti S,Rontauroli S,Guglielmelli P,Salati S,Rossi C,Zini R,Tagliafico E,Vannucchi AM,Manfredini R
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Fri Jan 13 00:00:00 EST 2017
EBI2 receptor regulates myelin development and inhibits LPC-induced demyelination.
Journal of neuroinflammation
Rutkowska A,Sailer AW,Dev KK
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Sat Dec 16 00:00:00 EST 2017
Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer.
Clinical epigenetics
Clermont PL,Crea F,Chiang YT,Lin D,Zhang A,Wang JZ,Parolia A,Wu R,Xue H,Wang Y,Ding J,Thu KL,Lam WL,Shah SP,Collins CC,Wang Y,Helgason CD
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Fri Apr 22 00:00:00 EDT 2016
miR-382-5p Controls Hematopoietic Stem Cell Differentiation Through the Downregulation of MXD1.
Stem cells and development
Zini R,Rossi C,Norfo R,Pennucci V,Barbieri G,Ruberti S,Rontauroli S,Salati S,Bianchi E,Manfredini R
PA116889 was used in western blot to explore the role of miR-382-5p in normal hematopoiesis
Sat Oct 01 00:00:00 EDT 2016
MyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity.
PloS one
Collinson-Pautz MR,Slawin KM,Levitt JM,Spencer DM
PA116889 was used in western blot to assess the effects of a genetically encoded chimeric MyD88/CD40 adjuvant
Wed May 31 00:00:00 EDT 2017
Dose-dependent autophagic effect of titanium dioxide nanoparticles in human HaCaT cells at non-cytotoxic levels.
Journal of nanobiotechnology
Lopes VR,Loitto V,Audinot JN,Bayat N,Gutleb AC,Cristobal S
Published figure using beta Actin polyclonal antibody (Product # PA1-16889) in Western Blot
Tue Mar 22 00:00:00 EDT 2016
MYB controls erythroid versus megakaryocyte lineage fate decision through the miR-486-3p-mediated downregulation of MAF.
Cell death and differentiation
Bianchi E,Bulgarelli J,Ruberti S,Rontauroli S,Sacchi G,Norfo R,Pennucci V,Zini R,Salati S,Prudente Z,Ferrari S,Manfredini R
PA1-16889 was used in western blot to demonstrate that MYB affects lineage fate decision through the transactivation of miR-486-3p expression and MAF downregulation.
Tue Dec 01 00:00:00 EST 2015
Evaluation of PAX5 gene in the early stages of leukemic B cells in the childhood B cell acute lymphoblastic leukemia.
Leukemia research
Firtina S,Sayitoglu M,Hatirnaz O,Erbilgin Y,Oztunc C,Cinar S,Yildiz I,Celkan T,Anak S,Unuvar A,Devecioglu O,Timur C,Aydogan G,Akcay A,Atay D,Turkkan E,Karaman S,Orhaner B,Sarper N,Deniz G,Ozbek U
PA1-16889 was used in western blot to study the expression of the PAX5 gene and the presence of transactivation domain mutations in B cells of childhood B cell acute lymphoblastic leukemia
Sun Jan 01 00:00:00 EST 2012
DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes.
Journal of lipid research
Harris CA,Haas JT,Streeper RS,Stone SJ,Kumari M,Yang K,Han X,Brownell N,Gross RW,Zechner R,Farese RV
PA1-16889 was used in western blot to study the role of DGAT enzymes in triacylglycerol synthesis and lipid droplets in adipocytes
Fri Apr 01 00:00:00 EDT 2011
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation.
Nature genetics
Wang J,Hevi S,Kurash JK,Lei H,Gay F,Bajko J,Su H,Sun W,Chang H,Xu G,Gaudet F,Li E,Chen T
PA1-16889 was used in western blot to investigate the role of KDM1 in the regulation of DNA methylation
Thu Jan 01 00:00:00 EST 2009
