Invitrogen

beta Catenin Polyclonal Antibody (CAT-15)

Advanced Verification

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

75 Published Figures

122 References

View all (242) beta Catenin antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

beta Catenin Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 88

beta Catenin Antibody (71-2700) in ICC/IF

HeLa cells were plated on coverslips overnight. The next day the cells were fixed and permeabilized using the Image-iT® Fixation/Permeabilization Kit (Product # R37602) according to protocol. Cells were then incubated with 3 µg/mL anti-B-catenin antibody (Product # 71-2700) for 60 min at room temperature followed by three washes with dPBS. Cells were then incubated with a 1:1000 dilution of goat anti-rabbit... View More

beta Catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

beta Catenin Antibody in Immunoprecipitation (IP)

beta Catenin Antibody in Western Blot (WB)

beta Catenin Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

beta Catenin Antibody in Western Blot, Immunohistochemistry (Paraffin) (WB, IHC (P))

beta Catenin Antibody in Immunohistochemistry (Frozen) (IHC (F))

beta Catenin Antibody in Western Blot, Immunohistochemistry (WB, IHC)

beta Catenin Antibody in Immunohistochemistry (IHC)

beta Catenin Antibody in ChIP Assay (ChIP)

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Product Details

71-2700

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

View 44 publications 44 publications

Immunohistochemistry (IHC)

View 19 publications 19 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

View 3 publications 3 publications

Immunohistochemistry (Frozen) (IHC (F))

View 5 publications 5 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 34 publications 34 publications

ELISA (ELISA)

0.1-1 mg/mL

Immunoprecipitation (IP)

5-10 µg

View 4 publications 4 publications

ChIP assay (ChIP)

View 9 publications 9 publications

Miscellaneous PubMed (Misc)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Chicken, Human, Mouse, Rat, Xenopus

Published species

Amphibian, Avian, Dog, Human, Mouse, Pig, Rabbit, Rat, Xenopus

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Clone

CAT-15

Immunogen

A 15-amino acid synthetic peptide derived from the C-terminus of the human/mouse beta-catenin protein.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533982

Product Specific Information

This antibody can be used to specifically immunoprecipitate the ~ 92 kDa beta-catenin protein from native cell lysates. It is suitable for use in immunoprecipitation (IP) and IP/western applications. Note that when the antibody is used for straight western blotting, cross-reactivity with a ~100 kDa protein of unknown identity is sometimes observed. Suggested positive control lysates include HeLa and A431.

Target Information

Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis. Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats. A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development. In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation. The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Sirtuin 6 Overexpression Improves Rotator Cuff Tendon-to-Bone Healing in the Aged.

Cells

Moon YJ,Cui B,Cho SY,Hwang JW,Chung HC,Kwon J,Kim D,Jang KY,Kim JR,Wang SI

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Thu Aug 10 00:00:00 EDT 2023

Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling.

iScience

Knop JL,Burkard N,Danesh M,Kintrup S,Dandekar T,Srivastava M,Springer R,Hiermaier M,Wagner NM,Waschke J,Flemming S,Schlegel N

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Fri Oct 20 00:00:00 EDT 2023

Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis.

iScience

Azbazdar Y,Tejeda-Munoz N,Monka JC,Dayrit A,Binder G,Ozhan G,De Robertis EM

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Fri Oct 20 00:00:00 EDT 2023

Multi-Targeting Approach in Glioblastoma Using Computer-Assisted Drug Discovery Tools to Overcome the Blood-Brain Barrier and Target EGFR/PI3Kp110β Signaling.

Cancers

Franco C,Kausar S,Silva MFB,Guedes RC,Falcao AO,Brito MA

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Tue Jul 19 00:00:00 EDT 2022

Shielding of actin by the endoplasmic reticulum impacts nuclear positioning.

Nature communications

Janota CS,Pinto A,Pezzarossa A,Machado P,Costa J,Campinho P,Franco CA,Gomes ER

71-2700 was used in Immunocytochemistry to suggest that the ER mediates asymmetric nucleo-cytoskeleton connections to position the nucleus.

Thu May 19 00:00:00 EDT 2022

A Drug Screening Reveals Minocycline Hydrochloride as a Therapeutic Option to Prevent Breast Cancer Cells Extravasation across the Blood-Brain Barrier.

Biomedicines

Godinho-Pereira J,Lopes MD,Garcia AR,Botelho HM,Malhó R,Figueira I,Brito MA

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Tue Aug 16 00:00:00 EDT 2022

PA1 participates in the maintenance of blood-testis barrier integrity via cooperation with JUN in the Sertoli cells of mice.

Cell & bioscience

Liu B,Liu C,Ma B,Zhang R,Zhao Z,Xiao S,Cao W,Ma Y,Zhu G,Li W,Li Z

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunohistochemistry

Mon Apr 04 00:00:00 EDT 2022

PA1 participates in the maintenance of blood-testis barrier integrity via cooperation with JUN in the Sertoli cells of mice.

Cell & bioscience

Liu B,Liu C,Ma B,Zhang R,Zhao Z,Xiao S,Cao W,Ma Y,Zhu G,Li W,Li Z

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunohistochemistry

Mon Apr 04 00:00:00 EDT 2022

3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-caffeoylquinic acid (TCQA).

Cells

Bejaoui M,Oliva AK,Ke MS,Ferdousi F,Isoda H

71-2700 was used in Western Blotting to compare the expression of signalling molecules and metabolism-associated proteins of DPCs treated with minoxidil (an FDA-approved drug for hair loss treatment) and 3,4,5-tri-O-caffeoylquinic acid (TCQA) (recently found to induce hair growth in vitro and in vivo) in 3D spheroid hanging drops and a 2D monolayer using DNA microarray analysis.

Thu Jun 30 00:00:00 EDT 2022

EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS ^G12D tumor development and propagation.

eLife

Pribluda A,Daemen A,Lima AN,Wang X,Hafner M,Poon C,Modrusan Z,Katakam AK,Foreman O,Eastham J,Hung J,Haley B,Garcia JT,Jackson EL,Junttila MR

71-2700 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, ChIP Assay to reveal EHMT2 as a critical regulator of Wnt signaling, implicating Ehmt2 as a potential target in lung cancer and other AT2-mediated lung pathologies.

Fri Aug 19 00:00:00 EDT 2022

Lysosomes are required for early dorsal signaling in the Xenopus embryo.

Proceedings of the National Academy of Sciences of the United States of America

Tejeda-Muñoz N,De Robertis EM

71-2700 was used in Immunocytochemistry to report that cathepsin D was activated in lysosomes specifically on the dorsal marginal zone of the embryo at the 64-cell stage, long before zygotic transcription starts.

Tue Apr 26 00:00:00 EDT 2022

Hedgehog regulation of epithelial cell state and morphogenesis in the larynx.

eLife

Ramachandran J,Zhou W,Bardenhagen AE,Nasr T,Yates ER,Zorn AM,Ji H,Vokes SA

71-2700 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to propose that SHH signaling has a default role in maintaining epithelial identity throughout the anterior foregut and that regionalized reductions in SHH trigger epithelial remodeling.

Fri Nov 18 00:00:00 EST 2022

Jamming Transitions in Astrocytes and Glioblastoma Are Induced by Cell Density and Tension.

Cells

Hohmann U,von Widdern JC,Ghadban C,Giudice MCL,Lemahieu G,Cavalcanti-Adam EA,Dehghani F,Hohmann T

71-2700 was used in Immunocytochemistry-immunofluorescence to analyze collective migration dynamics of astrocytes and glioblastoma cells using live cell imaging.

Wed Dec 21 00:00:00 EST 2022

Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause.

Nature genetics

Zhou J,Azizan EAB,Cabrera CP,Fernandes-Rosa FL,Boulkroun S,Argentesi G,Cottrell E,Amar L,Wu X,O'Toole S,Goodchild E,Marker A,Senanayake R,Garg S,Åkerström T,Backman S,Jordan S,Polubothu S,Berney DM,Gluck A,Lines KE,Thakker RV,Tuthill A,Joyce C,Kaski JP,Karet Frankl FE,Metherell LA,Teo AED,Gurnell M,Parvanta L,Drake WM,Wozniak E,Klinzing D,Kuan JL,Tiang Z,Gomez Sanchez CE,Hellman P,Foo RSY,Mein CA,Kinsler VA,Björklund P,Storr HL,Zennaro MC,Brown MJ

71-2700 was used in Immunocytochemistry to identify gain-of-function mutations in both CTNNB1 and GNA11 by whole-exome sequencing of 3/41 aldosterone-producing adenomas.

Wed Sep 01 00:00:00 EDT 2021

Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration.

Current biology : CB

Calero-Cuenca FJ,Osorio DS,Carvalho-Marques S,Sridhara SC,Oliveira LM,Jiao Y,Diaz J,Janota CS,Cadot B,Gomes ER

71-2700 was used in Immunocytochemistry to study Ctdnep1 and Eps8L2 interactions and demonstrate how these interactions are important for nuclear positioning and cell migration.

Mon Apr 12 00:00:00 EDT 2021

Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration.

Current biology : CB

Calero-Cuenca FJ,Osorio DS,Carvalho-Marques S,Sridhara SC,Oliveira LM,Jiao Y,Diaz J,Janota CS,Cadot B,Gomes ER

71-2700 was used in Immunocytochemistry to study Ctdnep1 and Eps8L2 interactions and demonstrate how these interactions are important for nuclear positioning and cell migration.

Mon Apr 12 00:00:00 EDT 2021

Food-Derived High Arginine Peptides Promote Spermatogenesis Recovery in Busulfan Treated Mice.

Frontiers in cell and developmental biology

Liu W,Zhang L,Gao A,Khawar MB,Gao F,Li W

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Sat Jan 08 00:00:00 EST 2022

Behind Brain Metastases Formation: Cellular and Molecular Alterations and Blood-Brain Barrier Disruption.

International journal of molecular sciences

Godinho-Pereira J,Garcia AR,Figueira I,Malhó R,Brito MA

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Wed Jun 30 00:00:00 EDT 2021

Behind Brain Metastases Formation: Cellular and Molecular Alterations and Blood-Brain Barrier Disruption.

International journal of molecular sciences

Godinho-Pereira J,Garcia AR,Figueira I,Malhó R,Brito MA

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Wed Jun 30 00:00:00 EDT 2021

Picturing Breast Cancer Brain Metastasis Development to Unravel Molecular Players and Cellular Crosstalk.

Cancers

Figueira I,Galego S,Custódio-Santos T,Vicente R,Molnár K,Haskó J,Malhó R,Videira M,Wilhelm I,Krizbai I,Brito MA

71-2700 was used in Immunocytochemistry to provide further understanding of BC brain metastasis formation, disclosing potential therapeutic targets.

Mon Feb 22 00:00:00 EST 2021

IL-20 Cytokines Are Involved in Epithelial Lesions Associated with Virus-Induced COPD Exacerbation in Mice.

Biomedicines

Le Roux M,Ollivier A,Kervoaze G,Beke T,Gillet L,Pichavant M,Gosset P

71-2700 was used in Immunohistochemistry to show that PVM infection and CS exposure additively upregulates the IL-20 pathway, leading to the promotion of epithelial damages.

Sun Dec 05 00:00:00 EST 2021

A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells.

eLife

Guo Q,Kim A,Li B,Ransick A,Bugacov H,Chen X,Lindström N,Brown A,Oxburgh L,Ren B,McMahon AP

71-2700 was used in ChIP assay to conclude that β-catenin's direct transcriptional role is restricted to the induction of NPCs, where rising β-catenin levels switch inhibitory TCF7L1/TCF7L2 complexes to activating LEF1/TCF7 complexes at primed gene targets poised for rapid initiation of a nephrogenic program.

Mon Feb 15 00:00:00 EST 2021

Pinhead antagonizes Admp to promote notochord formation.

iScience

Itoh K,Ossipova O,Sokol SY

71-2700 was used in Western Blot to evaluate the molecular targets and signaling mechanisms of the Pinhead protein during Xenopus gastrulation.

Fri Jun 25 00:00:00 EDT 2021

Myocyte Enhancer Factor 2C as a New Player in Human Breast Cancer Brain Metastases.

Cells

Galego S,Kauppila LA,Malhó R,Pimentel J,Brito MA

71-2700 was used in Immunocytochemistry to ascertain MEF2C expression in human BCBM, establish the relationship with disease severity, disclose the involvement of vascular endothelial growth factor receptor-2 (VEGFR-2) and β-catenin, also known as KDR and CTNNB1, respectively, and investigate if matched primary tumors express the protein.

Fri Feb 12 00:00:00 EST 2021

Osteocytes but not osteoblasts directly build mineralized bone structures.

International journal of biological sciences

Wang K,Ren Y,Lin S,Jing Y,Ma C,Wang J,Yuan XB,Han X,Zhao H,Wang Z,Zheng M,Xiao Y,Chen L,Olsen BR,Feng JQ

71-2700 was used in Western Blotting to study the ability of osteocytes and osteoblasts to directly build mineralized bone structures, and show that defects in osteocytes lead to the onset of hypophosphatemia rickets.

Wed Mar 16 00:00:00 EDT 2022

3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes.

Frontiers in cell and developmental biology

Bejaoui M,Villareal MO,Isoda H

71-2700 was used in Western Blot to suggest that 3,4,5-tri-O-caffeoylquinic acid (TCQA) can trigger β-catenin activation to enhance pigmentation during the anagen phase of the hair cycle.

Fri Nov 03 00:00:00 EDT 2023

3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes.

Frontiers in cell and developmental biology

Bejaoui M,Villareal MO,Isoda H

71-2700 was used in Western Blot to suggest that 3,4,5-tri-O-caffeoylquinic acid (TCQA) can trigger β-catenin activation to enhance pigmentation during the anagen phase of the hair cycle.

Fri Nov 03 00:00:00 EDT 2023

Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p.

International journal of molecular medicine

Cao Y,Lv W,Ding W,Li J

71-2700 was used in Western Blotting to determine the molecular mechanisms governing sevoflurane's action in hepatocellular carcinoma cells.

Wed Jul 01 00:00:00 EDT 2020

Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p.

International journal of molecular medicine

Cao Y,Lv W,Ding W,Li J

71-2700 was used in Western Blotting to determine the molecular mechanisms governing sevoflurane's action in hepatocellular carcinoma cells.

Wed Jul 01 00:00:00 EDT 2020

miR-187-3p increases gemcitabine sensitivity in breast cancer cells by targeting FGF9 expression.

Experimental and therapeutic medicine

Wu Y,Tao L,Liang J,Qiao Y,Liu W,Yu H,Yu X,Liu L

71-2700 was used in Western Blotting to elucidate the potential effects of miR-187-3p on gemcitabine sensitivity in the breast cancer cell line, MDA-MB-231 using reverse transcription quantitative-PCR, cell viability, flow cytometry, luciferase reporter assay and western blot analysis.

Sat Aug 01 00:00:00 EDT 2020

Evaluation of morphokinetic characteristics of zona pellucida free mouse pre-implantation embryos using time-lapse monitoring system.

The International journal of developmental biology

Kim J,Lee J,Choi YJ,Kwon O,Lee TB,Jun JH

71-2700 was used in Immunocytochemistry to compare the morphokinetic characteristics of ZP intact and ZP free mouse pre-implantation embryos with time-lapse monitoring system.

Thu Oct 14 00:00:00 EDT 2021

Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP.

Journal of extracellular vesicles

Li Z,Moniruzzaman M,Dastgheyb RM,Yoo SW,Wang M,Hao H,Liu J,Casaccia P,Nogueras-Ortiz C,Kapogiannis D,Slusher BS,Haughey NJ

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in ChIP assay

Tue Dec 01 00:00:00 EST 2020

Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP.

Journal of extracellular vesicles

Li Z,Moniruzzaman M,Dastgheyb RM,Yoo SW,Wang M,Hao H,Liu J,Casaccia P,Nogueras-Ortiz C,Kapogiannis D,Slusher BS,Haughey NJ

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in ChIP assay

Tue Dec 01 00:00:00 EST 2020

Endogenously produced LG3/4/5-peptide protects testes against toxicant-induced injury.

Cell death & disease

Li L,Mao B,Wu S,Li H,Lv L,Ge R,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Mon Jun 08 00:00:00 EDT 2020

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network.

eLife

Mukherjee S,Chaturvedi P,Rankin SA,Fish MB,Wlizla M,Paraiso KD,MacDonald M,Chen X,Weirauch MT,Blitz IL,Cho KW,Zorn AM

71-2700 was used in Chromatin immunoprecipitation to define the Sox17-governed endoderm gene regulatory network (GRN) in Xenopus gastrulae.

Mon Sep 07 00:00:00 EDT 2020

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network.

eLife

Mukherjee S,Chaturvedi P,Rankin SA,Fish MB,Wlizla M,Paraiso KD,MacDonald M,Chen X,Weirauch MT,Blitz IL,Cho KW,Zorn AM

71-2700 was used in Chromatin immunoprecipitation to define the Sox17-governed endoderm gene regulatory network (GRN) in Xenopus gastrulae.

Mon Sep 07 00:00:00 EDT 2020

Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen.

Poultry science

Pardyak L,Kaminska A,Brzoskwinia M,Hejmej A,Kotula-Balak M,Jankowski J,Ciereszko A,Bilinska B

71-2700 was used in Immunohistochemistry (Paraffin) to provide new information on the localization and expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys, and compare expression of junctional protein genes between 2 turkey population, one that produces white normal semen (WNS) and the other that produces yellow abnormal semen.

Wed Jan 01 00:00:00 EST 2020

Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen.

Poultry science

Pardyak L,Kaminska A,Brzoskwinia M,Hejmej A,Kotula-Balak M,Jankowski J,Ciereszko A,Bilinska B

Wed Jan 01 00:00:00 EST 2020

Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen.

Poultry science

Pardyak L,Kaminska A,Brzoskwinia M,Hejmej A,Kotula-Balak M,Jankowski J,Ciereszko A,Bilinska B

Wed Jan 01 00:00:00 EST 2020

Testin regulates the blood-testis barrier via disturbing occludin/ZO-1 association and actin organization.

Journal of cellular physiology

Su L,Wang Z,Xie S,Hu D,Cheng YC,Mruk DD,Guan Y

71-2700 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to suggest that besides as a monitor for Sertoli-germ cell junction integrity, testin is also an essential molecule to maintain Sertoli-Sertoli junctions.

Tue Sep 01 00:00:00 EDT 2020

ERK1/2 Phosphorylation of FHOD Connects Signaling and Nuclear Positioning Alternations in Cardiac Laminopathy.

Developmental cell

Antoku S,Wu W,Joseph LC,Morrow JP,Worman HJ,Gundersen GG

71-2700 was used in Immunocytochemistry-immunoflourescence to show that phosphorylation of FHOD proteins by ERK1/2 is a critical switch for nuclear positioning and may play a role in the pathogenesis of cardiomyopathy caused by LMNA mutations.

Mon Dec 02 00:00:00 EST 2019

Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β-catenin modulator Annexin A1.

EMBO reports

Rubinstein MR,Baik JE,Lagana SM,Han RP,Raab WJ,Sahoo D,Dalerba P,Wang TC,Han YW

71-2700 was used in Western Blotting to extend the "adenoma-carcinoma" model and identify microbes such as F. nucleatum as cancer "facilitators".

Mon Apr 01 00:00:00 EDT 2019

Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo.

Developmental biology

Bharathan NK,Dickinson AJG

71-2700 was used in Immunohistochemistry to study the role of Desmoplakin in the apical expansion of cells during radial intercalation.

Sat Jun 15 00:00:00 EDT 2019

[Di (2-ethylhexyl) phthalate-induced hypospadias in SD rats is related with Mafb expression: a transcriptome profiling-based study].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

Han X,Shao W,Yue Z,Xing L,Shen L,Long C,Zhang D,He D,Lin T,Wei G

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Tue Apr 30 00:00:00 EDT 2019

β-catenin-mediated hair growth induction effect of 3,4,5-tri-O-caffeoylquinic acid.

Aging

Bejaoui M,Villareal MO,Isoda H

71-2700 was used in Western Blotting to suggest that Β-catenin activation by TCQA promoted the initiation of the anagen phase of the hair cycle.

Sat Jun 29 00:00:00 EDT 2019

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

Nature communications

Shooshtarizadeh P,Helness A,Vadnais C,Brouwer N,Beauchemin H,Chen R,Bagci H,Staal FJT,Coté JF,Möröy T

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in ChIP assay

Wed Mar 20 00:00:00 EDT 2019

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

Nature communications

Shooshtarizadeh P,Helness A,Vadnais C,Brouwer N,Beauchemin H,Chen R,Bagci H,Staal FJT,Coté JF,Möröy T

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in ChIP assay

Wed Mar 20 00:00:00 EDT 2019

Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization.

Cell death & disease

Li L,Mao B,Yan M,Wu S,Ge R,Lian Q,Cheng CY

71-2700 was used in Immunohistochemistry-immunofluorescence to study the role of Dishevelled 3 in supporting Sertoli cell tight junction-permeability barrier function.

Tue Feb 26 00:00:00 EST 2019

α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart.

Development (Cambridge, England)

Vite A,Zhang C,Yi R,Emms S,Radice GL

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Thu Mar 08 00:00:00 EST 2018

Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis.

American journal of physiology. Endocrinology and metabolism

Wen Q,Tang EI,Lui WY,Lee WM,Wong CKC,Silvestrini B,Cheng CY

71-2700 was used in Western Blotting to investigate the role of dynein 1 in supporting the transport of spermatids and organelles across the seminiferous epithelium during spermatogenesis.

Thu Nov 01 00:00:00 EDT 2018

Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines.

Virulence

Liu J,Ma'ayeh S,Peirasmaki D,Lundström-Stadelmann B,Hellman L,Svärd SG

71-2700 was used in Western Blotting to characterise the role of the three main cysteine proteases secreted by Giardia intestinalis in the development of Giardiasis.

Mon Dec 31 00:00:00 EST 2018

Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines.

Virulence

Liu J,Ma'ayeh S,Peirasmaki D,Lundström-Stadelmann B,Hellman L,Svärd SG

71-2700 was used in Western Blotting to characterise the role of the three main cysteine proteases secreted by Giardia intestinalis in the development of Giardiasis.

Mon Dec 31 00:00:00 EST 2018

Development of a polarized pancreatic ductular cell epithelium for physiological studies.

Journal of applied physiology (Bethesda, Md. : 1985)

O'Malley Y,Rotti PG,Thornell IM,Vanegas Calderón OG,Febres-Aldana C,Durham K,Yao J,Li X,Zhu Z,Norris AW,Zabner J,Engelhardt JF,Uc A

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Sun Jul 01 00:00:00 EDT 2018

Downregulation of ROS1 enhances the therapeutic efficacy of arsenic trioxide in acute myeloid leukemia cell lines.

Oncology letters

Li J

71-2700 was used in Western Blotting to investigate the function of ROS proto-oncogene 1 receptor tyrosine kinase in regulating the migration and proliferation of acute myeloid leukaemia cells through Wnt/Β-catenin signalling, and in arsenic trioxide treatment.

Fri Jun 01 00:00:00 EDT 2018

Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis.

Cell death & disease

Wen Q,Li N,Xiao X,Lui WY,Chu DS,Wong CKC,Lian Q,Ge R,Lee WM,Silvestrini B,Cheng CY

71-2700 was used in Immunohistochemistry to demonstrate that Spire 1 is an ectoplasmic specialization regulator to support germ cell development during spermatogenesis.

Mon Feb 12 00:00:00 EST 2018

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion.

Nature cell biology

Labernadie A,Kato T,Brugués A,Serra-Picamal X,Derzsi S,Arwert E,Weston A,González-Tarragó V,Elosegui-Artola A,Albertazzi L,Alcaraz J,Roca-Cusachs P,Sahai E,Trepat X

71-2700 was used in Immunohistochemistry to investigate the interactions between cancer-associated fibroblasts and cancer cells which drive cooperative tumour invasion.

Wed Mar 01 00:00:00 EST 2017

Antagonistic Activities of Sox2 and Brachyury Control the Fate Choice of Neuro-Mesodermal Progenitors.

Developmental cell

Koch F,Scholze M,Wittler L,Schifferl D,Sudheer S,Grote P,Timmermann B,Macura K,Herrmann BG

71-2700 was used in Chromatin immunoprecipitation to determine the roles and interactions of Sox2, Brachyury and Tbx6 in neuro-mesodermal progenitor potency and lineage choice.

Mon Sep 11 00:00:00 EDT 2017

Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs.

Development (Cambridge, England)

Stevens ML,Chaturvedi P,Rankin SA,Macdonald M,Jagannathan S,Yukawa M,Barski A,Zorn AM

71-2700 was used in Chromatin immunoprecipitation to identify the transcriptomes of Xenopus foregut and hindgut progenitors, which are conserved with mammals.

Sat Apr 01 00:00:00 EDT 2017

Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Gao Y,Mruk D,Chen H,Lui WY,Lee WM,Cheng CY

712700 was used in immunocytochemistry and western blot to explore how laminin2 in the basement membrane modulates the blood testis barrier dynamics during spermatogenesis

Wed Feb 01 00:00:00 EST 2017

DTX3L is upregulated in glioma and is associated with glioma progression.

International journal of molecular medicine

Xu P,Tao X,Zhao C,Huang Q,Chang H,Ban N,Bei Y,Xia X,Shen C,Wang K,Xu L,Wu P,Ren J,Wang D

71-2700 was used in Western Blotting to investigate the clinical significance and biological function of Deltex-3-like in human glioma.

Tue Aug 01 00:00:00 EDT 2017

Basement Membrane Laminin α2 Regulation of BTB Dynamics via Its Effects on F-Actin and Microtubule Cytoskeletons Is Mediated Through mTORC1 Signaling.

Endocrinology

Gao Y,Chen H,Lui WY,Lee WM,Cheng CY

71-2700 was used in Western Blotting to study the mechanism of laminin α2-mediated regulation in Sertoli cell blood-testes barrier dynamics.

Sat Apr 01 00:00:00 EDT 2017

Bioengineered Submucosal Organoids for In Vitro Modeling of Colorectal Cancer.

Tissue engineering. Part A

Devarasetty M,Skardal A,Cowdrick K,Marini F,Soker S

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunohistochemistry

Sun Oct 01 00:00:00 EDT 2017

Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2.

Scientific reports

Gao Y,Chen H,Xiao X,Lui WY,Lee WM,Mruk DD,Cheng CY

71-2700 was used in Immunocytochemistry-immunoflourescence to investigate the effect of PFOS on Setoli cell blood-testis barrier, showing that injury occurs via Akt1/2 and disrupts F-actin and microtubule organization.

Mon Apr 24 00:00:00 EDT 2017

Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2.

Scientific reports

Gao Y,Chen H,Xiao X,Lui WY,Lee WM,Mruk DD,Cheng CY

Mon Apr 24 00:00:00 EDT 2017

Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2.

Scientific reports

Gao Y,Chen H,Xiao X,Lui WY,Lee WM,Mruk DD,Cheng CY

Mon Apr 24 00:00:00 EDT 2017

Intra-axonal Synthesis of SNAP25 Is Required for the Formation of Presynaptic Terminals.

Cell reports

Batista AFR,Martínez JC,Hengst U

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Tue Sep 26 00:00:00 EDT 2017

Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice.

Nature communications

Xiang FL,Fang M,Yutzey KE

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in ChIP assay

Thu Sep 28 00:00:00 EDT 2017

Aroclor1254 disrupts the blood-testis barrier by promoting endocytosis and degradation of junction proteins via p38 MAPK pathway.

Cell death & disease

Jia X,Xu Y,Wu W,Fan Y,Wang G,Zhang T,Su W

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Thu May 25 00:00:00 EDT 2017

Aroclor1254 disrupts the blood-testis barrier by promoting endocytosis and degradation of junction proteins via p38 MAPK pathway.

Cell death & disease

Jia X,Xu Y,Wu W,Fan Y,Wang G,Zhang T,Su W

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Thu May 25 00:00:00 EDT 2017

Aroclor1254 disrupts the blood-testis barrier by promoting endocytosis and degradation of junction proteins via p38 MAPK pathway.

Cell death & disease

Jia X,Xu Y,Wu W,Fan Y,Wang G,Zhang T,Su W

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Thu May 25 00:00:00 EDT 2017

Aroclor1254 disrupts the blood-testis barrier by promoting endocytosis and degradation of junction proteins via p38 MAPK pathway.

Cell death & disease

Jia X,Xu Y,Wu W,Fan Y,Wang G,Zhang T,Su W

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunocytochemistry

Thu May 25 00:00:00 EDT 2017

Wnt11 regulates cardiac chamber development and disease during perinatal maturation.

JCI insight

Touma M,Kang X,Gao F,Zhao Y,Cass AA,Biniwale R,Xiao X,Eghbali M,Coppola G,Reemtsen B,Wang Y

71-2700 was used in Western Blot to show Wnt11-mediated signalling promotes the chamber-specific growth of the neonatal heart and influences pathogenesis in response to hypoxia and cyanotic congenital heart defect.

Thu Sep 07 00:00:00 EDT 2017

The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent.

eNeuro

Acharya KD,Nettles SA,Sellers KJ,Im DD,Harling M,Pattanayak C,Vardar-Ulu D,Lichti CF,Huang S,Edwards DP,Srivastava DP,Denner L,Tetel MJ

71-2700 was used in Western Blot to provide evidence for novel functions of progestin receptor (PR) in synaptic modulation and energy homeostasis to affect health and disease.

Wed May 30 00:00:00 EDT 2018

Hemodynamics associated with atrial fibrillation directly alters thrombotic potential of endothelial cells.

Thrombosis research

Simmers MB,Cole BK,Ogletree ML,Chen Z,Xu Y,Kong LJ,Mackman N,Blackman BR,Wamhoff BR

71-2700 was used in immunocytochemistry to study the direct alteration of thrombotic potential of endothelial cells and the hemodynamics associated with atrial fibrillation

Fri Jul 01 00:00:00 EDT 2016

N-Cadherin Regulates Cell Migration Through a Rab5-Dependent Temporal Control of Macropinocytosis.

Traffic (Copenhagen, Denmark)

Wen MH,Wang JY,Chiu YT,Wang MP,Lee SP,Tai CY

71-2700 was used in Immunocytochemistry to study the involvement of N-cadherin in the maturation of macropinocytosis through Rab5 recruitment, linking macropinocytosis and cell migration.

Fri Jul 01 00:00:00 EDT 2016

Interleukin 1alpha-induced disruption of the Sertoli cell cytoskeleton affects gap junctional communication.

Cellular signalling

Chojnacka K,Bilinska B,Mruk DD

71-2700 was used in immunocytochemistry and western blot to characterize disruption of the sertolic cell cytoskeleton by interleukin 1alpha and its affect on gap junctional communication

Sun May 01 00:00:00 EDT 2016

A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening.

Biotechnology and bioengineering

Skardal A,Devarasetty M,Forsythe S,Atala A,Soker S

71-2700 was used in immunohistochemistry - paraffin section to study an in vitro model for tumor progression modeling and drug screening by using a reductionist metastasis-on-a-chip platform

Thu Sep 01 00:00:00 EDT 2016

Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells.

Scientific reports

Gao Y,Lui WY,Lee WM,Cheng CY

71-2700 was used in immunocytochemistry and western blot report that crumbs homolog 3 is an actin microfilament regulator

Thu Jun 30 00:00:00 EDT 2016

Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells.

Scientific reports

Gao Y,Lui WY,Lee WM,Cheng CY

71-2700 was used in immunocytochemistry and western blot report that crumbs homolog 3 is an actin microfilament regulator

Thu Jun 30 00:00:00 EDT 2016

Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis.

Scientific reports

Shukla S,Sinha S,Khan S,Kumar S,Singh K,Mitra K,Maurya R,Meeran SM

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Wed Feb 24 00:00:00 EST 2016

Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis.

Scientific reports

Shukla S,Sinha S,Khan S,Kumar S,Singh K,Mitra K,Maurya R,Meeran SM

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Wed Feb 24 00:00:00 EST 2016

Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis.

Scientific reports

Shukla S,Sinha S,Khan S,Kumar S,Singh K,Mitra K,Maurya R,Meeran SM

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Wed Feb 24 00:00:00 EST 2016

Glucose-Induced Oxidative Stress Reduces Proliferation in Embryonic Stem Cells via FOXO3A/β-Catenin-Dependent Transcription of p21(cip1).

Stem cell reports

McClelland Descalzo DL,Satoorian TS,Walker LM,Sparks NR,Pulyanina PY,Zur Nieden NI

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Tue Jul 12 00:00:00 EDT 2016

Glucose-Induced Oxidative Stress Reduces Proliferation in Embryonic Stem Cells via FOXO3A/β-Catenin-Dependent Transcription of p21(cip1).

Stem cell reports

McClelland Descalzo DL,Satoorian TS,Walker LM,Sparks NR,Pulyanina PY,Zur Nieden NI

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Tue Jul 12 00:00:00 EDT 2016

Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier.

Spermatogenesis

Li N,Lee WM,Cheng CY

712700 was used in immunocytochemistry and western blot to examine the organization of actin microfilaments in Sertoli cell at the blood testis barrier

Fri Apr 01 00:00:00 EDT 2016

Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Li N,Mruk DD,Wong CK,Lee WM,Han D,Cheng CY

71-2700 was used in immunohistochemistry and western blot to study the role of plastin 3 in ectoplasmic specialization dynamics during spermatogenesis in the rat testis

Tue Sep 01 00:00:00 EDT 2015

Flutamide alters the distribution of c-Src and affects the N-cadherin-β-catenin complex in the seminiferous epithelium of adult rat.

Andrology

Zarzycka M,Chojnacka K,Mruk DD,Gorowska E,Hejmej A,Kotula-Balak M,Pardyak L,Bilinska B

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunohistochemistry (Paraffin)

Fri May 01 00:00:00 EDT 2015

Flutamide alters the distribution of c-Src and affects the N-cadherin-β-catenin complex in the seminiferous epithelium of adult rat.

Andrology

Zarzycka M,Chojnacka K,Mruk DD,Gorowska E,Hejmej A,Kotula-Balak M,Pardyak L,Bilinska B

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunohistochemistry (Paraffin)

Fri May 01 00:00:00 EDT 2015

Flutamide alters the distribution of c-Src and affects the N-cadherin-β-catenin complex in the seminiferous epithelium of adult rat.

Andrology

Zarzycka M,Chojnacka K,Mruk DD,Gorowska E,Hejmej A,Kotula-Balak M,Pardyak L,Bilinska B

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunohistochemistry (Paraffin)

Fri May 01 00:00:00 EDT 2015

Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro.

Annals of biomedical engineering

Skardal A,Devarasetty M,Rodman C,Atala A,Soker S

71-2700 was used in immunocytochemistry and immunohistochemistry to investigate using liver-tumor organoids for in vitro modeling of liver metastasis

Thu Oct 01 00:00:00 EDT 2015

Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress.

Molecular biology of the cell

ErLin S,WenJie W,LiNing W,BingXin L,MingDe L,Yan S,RuiFa H

71-2700 was used in western blot to study the role of Musashi-1 in blood-testis barrier structure during spermatogenesis

Fri May 15 00:00:00 EDT 2015

Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress.

Molecular biology of the cell

ErLin S,WenJie W,LiNing W,BingXin L,MingDe L,Yan S,RuiFa H

71-2700 was used in western blot to study the role of Musashi-1 in blood-testis barrier structure during spermatogenesis

Fri May 15 00:00:00 EDT 2015

Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress.

Molecular biology of the cell

ErLin S,WenJie W,LiNing W,BingXin L,MingDe L,Yan S,RuiFa H

71-2700 was used in western blot to study the role of Musashi-1 in blood-testis barrier structure during spermatogenesis

Fri May 15 00:00:00 EDT 2015

Flutamide alters β-catenin expression and distribution, and its interactions with E-cadherin in the porcine corpus luteum of mid- and late pregnancy.

Histology and histopathology

Grzesiak M,Mitan A,Janik ME,Knapczyk-Stwora K,Slomczynska M

71-2700 was used in immunohistochemistry, immunoprecipitation, and western blot to test if flutamide-induced androgen deficiency during mid- and late pregnancy alters luteal expression of adherens junction protein, beta-catenin, and E-cadherin

Sun Nov 01 00:00:00 EDT 2015

Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins.

Human reproduction (Oxford, England)

Xiao X,Mruk DD,Tang EI,Wong CK,Lee WM,John CM,Turek PJ,Silvestrini B,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Sun Jun 01 00:00:00 EDT 2014

rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9.

Journal of cell science

Mok KW,Mruk DD,Cheng CY

Sat Nov 15 00:00:00 EST 2014

Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr(407): an in vitro study.

Endocrinology

Wan HT,Mruk DD,Wong CK,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Wed Jan 01 00:00:00 EST 2014

c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution.

American journal of physiology. Endocrinology and metabolism

Xiao X,Mruk DD,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Tue Jan 15 00:00:00 EST 2013

Intercellular adhesion molecule-2 is involved in apical ectoplasmic specialization dynamics during spermatogenesis in the rat.

The Journal of endocrinology

Xiao X,Cheng CY,Mruk DD

71-2700 was used in western blot to assess the role of intercellular adhesion molecule-2 in the testis

Tue Jan 01 00:00:00 EST 2013

Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*.

PloS one

Qian X,Mruk DD,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Mon Sep 23 00:00:00 EDT 2013

Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*.

PloS one

Qian X,Mruk DD,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Mon Sep 23 00:00:00 EDT 2013

Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*.

PloS one

Qian X,Mruk DD,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Mon Sep 23 00:00:00 EDT 2013

Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat.

Proceedings of the National Academy of Sciences of the United States of America

Lie PP,Mruk DD,Mok KW,Su L,Lee WM,Cheng CY

Tue Jul 31 00:00:00 EDT 2012

Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat.

Proceedings of the National Academy of Sciences of the United States of America

Lie PP,Mruk DD,Mok KW,Su L,Lee WM,Cheng CY

Tue Jul 31 00:00:00 EDT 2012

Regulation of the blood-testis barrier by coxsackievirus and adenovirus receptor.

American journal of physiology. Cell physiology

Su L,Mruk DD,Cheng CY

Mon Oct 15 00:00:00 EDT 2012

Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis.

Molecular and cellular biology

Swope D,Cheng L,Gao E,Li J,Radice GL

Thu Mar 01 00:00:00 EST 2012

Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis.

Molecular and cellular biology

Swope D,Cheng L,Gao E,Li J,Radice GL

Thu Mar 01 00:00:00 EST 2012

Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis.

Molecular and cellular biology

Swope D,Cheng L,Gao E,Li J,Radice GL

Thu Mar 01 00:00:00 EST 2012

Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis.

Molecular and cellular biology

Swope D,Cheng L,Gao E,Li J,Radice GL

Thu Mar 01 00:00:00 EST 2012

Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis.

Endocrinology

Su W,Mruk DD,Lie PP,Lui WY,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Mon Oct 01 00:00:00 EDT 2012

Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis.

Endocrinology

Su W,Mruk DD,Lie PP,Lui WY,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Mon Oct 01 00:00:00 EDT 2012

Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis.

Endocrinology

Su W,Mruk DD,Lie PP,Lui WY,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Mon Oct 01 00:00:00 EDT 2012

Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis.

Endocrinology

Su W,Mruk DD,Lie PP,Lui WY,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Western Blot

Mon Oct 01 00:00:00 EDT 2012

Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.

Genesis (New York, N.Y. : 2000)

Swope D,Li J,Muller EJ,Radice GL

71-2700 was used in western blot to study plakoglobin using hypomorphic mice.

Mon Oct 01 00:00:00 EDT 2012

Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.

Genesis (New York, N.Y. : 2000)

Swope D,Li J,Muller EJ,Radice GL

71-2700 was used in western blot to study plakoglobin using hypomorphic mice.

Mon Oct 01 00:00:00 EDT 2012

Tumor necrosis factor α-mediated restructuring of the Sertoli cell barrier in vitro involves matrix metalloprotease 9 (MMP9), membrane-bound intercellular adhesion molecule-1 (ICAM-1) and the actin cytoskeleton.

Spermatogenesis

Lydka M,Bilinska B,Cheng CY,Mruk DD

71-2700 was used in western blot to examine the effects of TNFalpha on Sertoli cell barrier function

Mon Oct 01 00:00:00 EDT 2012

Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis.

Spermatogenesis

Tang EI,Xiao X,Mruk DD,Qian XJ,Mok KW,Jenardhanan P,Lee WM,Mathur PP,Cheng CY

71-2700 was used in immunoprecipitation to examine the role of actin and tubulin in ectoplasmic specialization

Sun Apr 01 00:00:00 EDT 2012

Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal.

Nature cell biology

Yi F,Pereira L,Hoffman JA,Shy BR,Yuen CM,Liu DR,Merrill BJ

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in ChIP assay

Sun Jun 19 00:00:00 EDT 2011

c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes.

The international journal of biochemistry & cell biology

Xiao X,Mruk DD,Lee WM,Cheng CY

71-2700 was used in western blot to elucidate how c-Yes regulates the blood-testis barrier and apical ectoplasmic specialization integrity.

Fri Apr 01 00:00:00 EDT 2011

Drug transporters and blood--testis barrier function.

The Journal of endocrinology

Su L,Mruk DD,Lee WM,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Wed Jun 01 00:00:00 EDT 2011

Drug transporters and blood--testis barrier function.

The Journal of endocrinology

Su L,Mruk DD,Lee WM,Cheng CY

Published figure using beta Catenin polyclonal antibody (Product # 71-2700) in Immunofluorescence

Wed Jun 01 00:00:00 EDT 2011

A study to assess the assembly of a functional blood-testis barrier in developing rat testes.

Spermatogenesis

Mok KW,Mruk DD,Lee WM,Cheng CY

71-2700 was used in Western Blotting to identify a precise time window when the blood-testis barrier is established in the developing rat testis during the final stage of cell cycle progression and meiosis.

Fri Jul 01 00:00:00 EDT 2011

A study to assess the assembly of a functional blood-testis barrier in developing rat testes.

Spermatogenesis

Mok KW,Mruk DD,Lee WM,Cheng CY

Fri Jul 01 00:00:00 EDT 2011

Different responses in transformation of MDCK cells in 2D and 3D culture by v-Src as revealed by microarray techniques, RT-PCR and functional assays.

Laboratory investigation; a journal of technical methods and pathology

Töyli M,Rosberg-Kulha L,Capra J,Vuoristo J,Eskelinen S

71-2700 was used in immunocytochemistry to study the differentiation and transformation of canine kidney MDCK cells cultured in either a 2D or 3D environment

Tue Jun 01 00:00:00 EDT 2010

The Wnt antagonists Frzb-1 and Crescent locally regulate basement membrane dissolution in the developing primary mouth.

Development (Cambridge, England)

Dickinson AJ,Sive HL

71-2700 was used in western blot to identify genes that contribute to primary mouth anlage

Wed Apr 01 00:00:00 EDT 2009

Drug transporter, P-glycoprotein (MDR1), is an integrated component of the mammalian blood-testis barrier.

The international journal of biochemistry & cell biology

Su L,Cheng CY,Mruk DD

71-2700 was used in immunocytochemistry to determine the role of P-glycoprotein in the blood-testis barrier

Tue Dec 01 00:00:00 EST 2009

Immunofluorescent analysis of connexin-43 using monoclonal antibodies to its extracellular domain.

Bulletin of experimental biology and medicine

Baklaushev VP,Gurina OI,Yusubalieva GM,Grinenko NF,Cytrin EB,Victorov IV,Chekhonin VP

71-2700 was used in immunohistochemistry - frozen section to assess the use of connexin-43 monoclonal antibodies

Thu Oct 01 00:00:00 EDT 2009

N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.

Journal of molecular and cellular cardiology

Li J,Levin MD,Xiong Y,Petrenko N,Patel VV,Radice GL

71-2700 was used in immunocytochemistry to explore the relationship between N-cadherin and connexin43 in the heart

Sat Mar 01 00:00:00 EST 2008

C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques.

Circulation research

Maass K,Shibayama J,Chase SE,Willecke K,Delmar M

71-2700 was used in Immunoprecipitation to conclude that the carboxyl-terminal domain of Cx43 is involved in regulating the localization, number and size of Cx43 plaques in vivo.

Fri Dec 07 00:00:00 EST 2007

Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis.

Journal of andrology

Mruk DD,Lau AS,Sarkar O,Xia W

71-2700 was used in Western Blotting to suggest that Rab4A participates in adherens junction dynamics in the testis.

Thu Dec 27 00:00:00 EST 2007

Disruption of Sertoli-germ cell adhesion function in the seminiferous epithelium of the rat testis can be limited to adherens junctions without affecting the blood-testis barrier integrity: an in vivo study using an androgen suppression model.

Journal of cellular physiology

Xia W,Wong CH,Lee NP,Lee WM,Cheng CY

71-2700 was used in immunohistochemistry - frozen section to study regulation of the blood-testis barrier

Sat Oct 01 00:00:00 EDT 2005

Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway.

Endocrinology

Wong CH,Mruk DD,Siu MK,Cheng CY

71-2700 was used in Immunohistochemistry-immunofluorescence to elucidate the regulation of blood-testis barrier dynamics by alpha(2)-macroglobulin.

Fri Apr 01 00:00:00 EST 2005

TGF-beta3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: An in vivo study.

Developmental biology

Xia W,Cheng CY

71-2700 was used in immunohistochemistry - frozen section to test if TGF-beta3 regulates anchoring junction dynamics in the blood-testis barrier

Fri Apr 15 00:00:00 EDT 2005

Differential expression of E-cadherin, N-cadherin and beta-catenin in proximal and distal segments of the rat nephron.

BMC physiology

Prozialeck WC,Lamar PC,Appelt DM

71-2700 was used in immunohistochemistry - frozen section to report the patterns of cadherin expression in frozen sections of adult rat kidney

Mon May 17 00:00:00 EDT 2004

Cadmium alters the localization of N-cadherin, E-cadherin, and beta-catenin in the proximal tubule epithelium.

Toxicology and applied pharmacology

Prozialeck WC,Lamar PC,Lynch SM

71-2700 was used in immunohistochemistry - frozen section to test if Cd affects cadherin-dependent junctions in the proximal tubule epithelium in vivo.

Sun Jun 15 00:00:00 EDT 2003

Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?

Biology of reproduction

Lee NP,Mruk D,Lee WM,Cheng CY

71-2700 was used in immunohistochemistry - frozen section to show that the cadherin/catenin complex is present between Sertoli and germ cells and is used for the assembly of functional adheren junctions.

Sat Feb 01 00:00:00 EST 2003

Bioinformatics

Protein Aliases: armadillo homolog; Bcatenin; beta 1 88kDa; beta catenin; Beta-catenin; Betacatenin; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; Catenin beta-1; Catenin beta1; Catenin β 1; Catenin β1; CTNB1; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; NYD-SP19; OTTHUMP00000209289; P14L; PP8304; RP5-1118M15.1; β catenin; βcatenin

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Gene Aliases: armadillo; B-catenin; beta-catenin; Bfc; Catnb; CHBCAT; CTNNB; CTNNB1; ctnnb1-a; ctnnb1-b; Mesc; MRD19; OK/SW-cl.35; PRO2286; XELAEV_18031149mg

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UniProt ID: (Human) P35222, (Mouse) Q02248, (Rat) Q9WU82

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Entrez Gene ID: (Chicken) 395964, (Human) 1499, (Mouse) 12387, (Rat) 84353, (Xenopus) 399274

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Function(s)

RNA polymerase II transcription factor binding RNA polymerase II activating transcription factor binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity signal transducer activity protein binding protein C-terminus binding transcription factor binding enzyme binding kinase binding protein kinase binding protein phosphatase binding estrogen receptor binding protein complex binding ionotropic glutamate receptor binding nuclear hormone receptor binding transcription regulatory region DNA binding ion channel binding alpha-catenin binding cadherin binding SMAD binding androgen receptor binding nitric-oxide synthase binding I-SMAD binding repressing transcription factor binding cadherin binding involved in cell-cell adhesion euchromatin binding DNA binding chromatin binding R-SMAD binding

Process(es)

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beta Catenin Polyclonal Antibody (CAT-15)

beta Catenin Antibody (71-2700) in ICC/IF

Product Details

71-2700

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

ELISA (ELISA)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

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