Invitrogen

delta Catenin Monoclonal Antibody (15D2)

Advanced Verification

This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.

24 Published Figures

21 References

View all (82) delta Catenin antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

delta Catenin Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 30

delta Catenin Antibody (33-9600) in ICC/IF

Immunofluorescent analysis of p120 Catenin (C-Term) was done on 70% confluent log phase U-2 OS cells. The cells were fixed with 4% paraformaldehyde for 15 minutes; permeabilized with 0.25% Triton™ X-100 for 10 minutes followed by blocking with 5% BSA for 1 hour at room temperature. The cells were incubated with p120 Catenin (C-Term) Mouse Monoclonal Antibody (Product # 33-9600) at 1 µg/mL in 1% BSA and incu... View More

delta Catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

delta Catenin Antibody in Western Blot (WB)

delta Catenin Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

delta Catenin Antibody in Immunohistochemistry (IHC)

delta Catenin Antibody in Western Blot, Immunohistochemistry (WB, IHC)

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Product Details

33-9600

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

View 10 publications 10 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

Assay-dependent

View 4 publications 4 publications

ELISA (ELISA)

Assay-dependent

Immunoprecipitation (IP)

Assay-dependent

Miscellaneous PubMed (Misc)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Published species

Deer, Dog, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

15D2

Immunogen

Recombinant fusion protein derived from the C-terminus of murine p120ct

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2533151

Target Information

Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hydrocephalus in Mice Is Underpinned by Changes in Ependymal Cell Physiology.

Cells

Harkins D,Harvey TJ,Atterton C,Miller I,Currey L,Oishi S,Kasherman M,Davila RA,Harris L,Green K,Piper H,Parton RG,Thor S,Cooper HM,Piper M

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Immunocytochemistry

Tue Aug 02 00:00:00 EDT 2022

Hydrocephalus in Mice Is Underpinned by Changes in Ependymal Cell Physiology.

Cells

Harkins D,Harvey TJ,Atterton C,Miller I,Currey L,Oishi S,Kasherman M,Davila RA,Harris L,Green K,Piper H,Parton RG,Thor S,Cooper HM,Piper M

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Immunocytochemistry

Tue Aug 02 00:00:00 EDT 2022

Adherens Junction Integrity Is a Critical Determinant of Sodium Iodide Symporter Residency at the Plasma Membrane of Thyroid Cells.

Cancers

Faria M,Vareda J,Miranda M,Bugalho MJ,Silva AL,Matos P

33-9600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to indicate that the loss of epithelial cell-cell adhesion may contribute to RAI refractoriness, indicating that in addition to stimulating NIS expression, successful resensitization therapies might require the employment of agents that improve cell-cell adhesion and NIS PM retention in refractory TC cells.

Mon Oct 31 00:00:00 EDT 2022

Adherens Junction Integrity Is a Critical Determinant of Sodium Iodide Symporter Residency at the Plasma Membrane of Thyroid Cells.

Cancers

Faria M,Vareda J,Miranda M,Bugalho MJ,Silva AL,Matos P

Mon Oct 31 00:00:00 EDT 2022

Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling.

The Journal of cell biology

Kourtidis A,Necela B,Lin WH,Lu R,Feathers RW,Asmann YW,Thompson EA,Anastasiadis PZ

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Immunofluorescence

Mon Oct 02 00:00:00 EDT 2017

Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling.

The Journal of cell biology

Kourtidis A,Necela B,Lin WH,Lu R,Feathers RW,Asmann YW,Thompson EA,Anastasiadis PZ

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Immunofluorescence

Mon Oct 02 00:00:00 EDT 2017

Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.

Molecular carcinogenesis

Wang R,Chen YS,Dashwood WM,Li Q,Löhr CV,Fischer K,Ho E,Williams DE,Dashwood RH

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Western Blot

Sat Jul 01 00:00:00 EDT 2017

Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer.

PloS one

Kourtidis A,Yanagisawa M,Huveldt D,Copland JA,Anastasiadis PZ

33-9600 was used in western blot to study the role of p20 phosphorylation in tumor transformation.

Tue Apr 26 00:00:00 EDT 2016

Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer.

PloS one

Kourtidis A,Yanagisawa M,Huveldt D,Copland JA,Anastasiadis PZ

33-9600 was used in western blot to study the role of p20 phosphorylation in tumor transformation.

Tue Apr 26 00:00:00 EDT 2016

Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer.

PloS one

Kourtidis A,Yanagisawa M,Huveldt D,Copland JA,Anastasiadis PZ

33-9600 was used in western blot to study the role of p20 phosphorylation in tumor transformation.

Tue Apr 26 00:00:00 EDT 2016

p120-catenin differentially regulates cell migration by Rho-dependent intracellular and secreted signals.

EMBO reports

Epifano C,Megias D,Perez-Moreno M

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Western Blot

Thu May 01 00:00:00 EDT 2014

CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions.

The Journal of cell biology

Shahbazi MN,Megias D,Epifano C,Akhmanova A,Gundersen GG,Fuchs E,Perez-Moreno M

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Western Blot

Mon Dec 23 00:00:00 EST 2013

CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions.

The Journal of cell biology

Shahbazi MN,Megias D,Epifano C,Akhmanova A,Gundersen GG,Fuchs E,Perez-Moreno M

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Western Blot

Mon Dec 23 00:00:00 EST 2013

CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions.

The Journal of cell biology

Shahbazi MN,Megias D,Epifano C,Akhmanova A,Gundersen GG,Fuchs E,Perez-Moreno M

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Western Blot

Mon Dec 23 00:00:00 EST 2013

The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development.

Developmental biology

Wang Q,Lin JL,Chan SY,Lin JJ

33-9600 was used in immunocytochemistry and western blot to study the intercalated disc of the heart.

Fri Feb 15 00:00:00 EST 2013

Targeting Src family kinases inhibits bevacizumab-induced glioma cell invasion.

PloS one

Huveldt D,Lewis-Tuffin LJ,Carlson BL,Schroeder MA,Rodriguez F,Giannini C,Galanis E,Sarkaria JN,Anastasiadis PZ

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Immunohistochemistry

Wed Aug 28 00:00:00 EDT 2013

Targeting Src family kinases inhibits bevacizumab-induced glioma cell invasion.

PloS one

Huveldt D,Lewis-Tuffin LJ,Carlson BL,Schroeder MA,Rodriguez F,Giannini C,Galanis E,Sarkaria JN,Anastasiadis PZ

Published figure using delta Catenin monoclonal antibody (Product # 33-9600) in Immunohistochemistry

Wed Aug 28 00:00:00 EDT 2013

Altered E-cadherin expression and p120 catenin localization in esophageal squamous cell carcinoma.

Annals of surgical oncology

Chung Y,Lam AK,Luk JM,Law S,Chan KW,Lee PY,Wong J

33-9600 was used in immunohistochemistry - paraffin section to assess the clinical significance of E-cadherin and p120ctn expression in esophageal squamous cell carcinoma

Thu Nov 01 00:00:00 EDT 2007

Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex.

Journal of cell science

Kim YJ,Sauer C,Testa K,Wahl JK,Svoboda RA,Johnson KR,Wheelock MJ,Knudsen KA

33-9600 was used in immunocytochemistry and western blot to identify and characterize a novel classical cadherin adhesion system

Thu Sep 01 00:00:00 EDT 2005

Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses.

Proceedings of the National Academy of Sciences of the United States of America

Tinkle CL,Lechler T,Pasolli HA,Fuchs E

Tue Jan 13 00:00:00 EST 2004

Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses.

Proceedings of the National Academy of Sciences of the United States of America

Tinkle CL,Lechler T,Pasolli HA,Fuchs E

Tue Jan 13 00:00:00 EST 2004

Regulation of cell-cell interactions by phosphatidic acid phosphatase 2b/VCIP.

The EMBO journal

Humtsoe JO,Feng S,Thakker GD,Yang J,Hong J,Wary KK

Tue Apr 01 00:00:00 EST 2003

Regulation of cell-cell interactions by phosphatidic acid phosphatase 2b/VCIP.

The EMBO journal

Humtsoe JO,Feng S,Thakker GD,Yang J,Hong J,Wary KK

Tue Apr 01 00:00:00 EST 2003

Cadherin junctions in mammary tumors.

Journal of mammary gland biology and neoplasia

Wheelock MJ,Soler AP,Knudsen KA

33-9600 was used in immunohistochemistry (paraffin) to discuss using expression of cadherins and catenins as prognosis markers for cancer.

Sun Jul 01 00:00:00 EDT 2001

Bioinformatics

Protein Aliases: Cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin-associated protein), delta 1; Catenin delta-1; catenin src; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); p120-catenin

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Gene Aliases: AA409437; AU019353; CAS; Catns; CTNND; CTNND1; KIAA0384; mKIAA0384; P120; p120(CAS); p120(CTN); P120CAS; P120CTN

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UniProt ID: (Human) O60716, (Mouse) P30999

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Entrez Gene ID: (Human) 1500, (Dog) 483489, (Mouse) 12388, (Rat) 311163

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Function(s)

receptor binding protein binding protein kinase binding cadherin binding cadherin binding involved in cell-cell adhesion protein phosphatase binding protein domain specific binding cell adhesion molecule binding intermediate filament binding protein

Process(es)

transcription, DNA-templated regulation of transcription, DNA-templated cell adhesion brain development Wnt signaling pathway single organismal cell-cell adhesion adherens junction organization negative regulation of canonical Wnt signaling pathway morphogenesis of a polarized epithelium salivary gland morphogenesis keratinocyte differentiation epithelial cell differentiation involved in salivary gland development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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delta Catenin Monoclonal Antibody (15D2)

delta Catenin Antibody (33-9600) in ICC/IF

Product Details

33-9600

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

ELISA (ELISA)

Immunoprecipitation (IP)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

Bioinformatics

Performance Guarantee

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