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eIF4G Antibody (PA5-96717) in IHC (P)
Immunohistochemistry analysis of eIF4G in paraffin-embedded human colon carcinoma. Samples were incubated with eIF4G Polyclonal antibody (Product # PA5-96717) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
PA5-96717
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human EIF4G1 (NP_8865533)
Conjugate
Form
Liquid
Concentration
1.4 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808519
Product Specific Information
Immunogen sequence: PEELLNGAPS PPAVDLSPVS EPEEQAKEVT ASMAPPTIPS ATPATAPSAT SPAQEEEMEE EEEEEEGEAG EAGEAESEKG GEELLPPEST PIPANLSQNL E; Positive Samples: THP-1
Target Information
The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686A1451; eIF-4-gamma 1; EIF4-gamma; eucaryotic translation initiation factor 4G; Eukaryotic translation initiation factor 4 gamma 1; eukaryotic translation initiation factor 4 gamma, 1; OTTHUMP00000210577; OTTHUMP00000210586; OTTHUMP00000210587; OTTHUMP00000210588; OTTHUMP00000210595; OTTHUMP00000210602; OTTHUMP00000210603; p220
Gene Aliases: EIF-4G1; EIF4F; EIF4G; EIF4G1; EIF4GI; P220; PARK18
UniProt ID: (Human) Q04637
Entrez Gene ID: (Human) 1981
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
nuclear-transcribed mRNA poly(A) tail shortening
behavioral fear response
translational initiation
regulation of translational initiation
viral process
regulation of mRNA stability
positive regulation of neuron differentiation
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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