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Invitrogen
gamma Catenin Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 9
gamma Catenin Antibody (PA5-29930) in ICC/IF
Immunofluorescence analysis of gamma Catenin was performed using 70% confluent log phase HaCaT cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with gamma Catenin Polyclonal Antibody (Product # PA5-29930) at 1:200 dilution in 0.1% BSA, incubated at 4 de... View More
Product Details
PA5-29930
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 503 and 725 of Human JUP
Conjugate
Form
Liquid
Concentration
0.36 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2547404
Product Specific Information
Recommended positive controls: A431.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (87%), Dog (99%), Pig (98%), Chicken (97%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gamma-catenin; Junction plakoglobin; OTTHUMP00000164735
Gene Aliases: ARVD12; CTNNG; D930025P04Rik; DP3; DPIII; JUP; PDGB; PG; PKGB
UniProt ID: (Human) P14923, (Mouse) Q02257
Entrez Gene ID: (Human) 3728, (Mouse) 16480
transcription coactivator activity
signal transducer activity
structural molecule activity
structural constituent of cell wall
protein binding
protein kinase binding
protein phosphatase binding
protein homodimerization activity
alpha-catenin binding
cadherin binding
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
cadherin binding involved in cell-cell adhesion
desmosome assembly
cytoskeletal anchoring at plasma membrane
signal transduction
single organismal cell-cell adhesion
cell migration
adherens junction organization
adherens junction assembly
regulation of cell proliferation
positive regulation of protein import into nucleus
skin development
detection of mechanical stimulus
positive regulation of sequence-specific DNA binding transcription factor activity
protein heterooligomerization
endothelial cell-cell adhesion
cellular response to indole-3-methanol
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
positive regulation of canonical Wnt signaling pathway
regulation of ventricular cardiac muscle cell action potential
cell adhesion
regulation of cell fate specification
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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