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Invitrogen
gamma Catenin Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 10
gamma Catenin Antibody (PA5-95204) in ICC/IF
Immunocytochemistry analysis of gamma Catenin using anti-gamma Catenin antibody (Product # PA5-95204) . gamma Catenin was detected in a section of A431 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 2μg/mL rabbit anti-gamma Catenin antibody (Product # PA5-95204) overnight at 4°C. DyLight... View More
Product Details
PA5-95204
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human gamma Catenin recombinant protein (Position: M556-A745).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807008
Product Specific Information
Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse and rat gamma Catenin.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; OTTHUMP00000164735
Gene Aliases: ARVD12; CTNNG; D930025P04Rik; DP3; DPIII; JUP; PDGB; PG; PKGB
UniProt ID: (Human) P14923, (Rat) Q6P0K8, (Mouse) Q02257
Entrez Gene ID: (Human) 3728, (Rat) 81679, (Mouse) 16480
transcription coactivator activity
signal transducer activity
structural molecule activity
structural constituent of cell wall
protein binding
protein kinase binding
protein phosphatase binding
protein homodimerization activity
alpha-catenin binding
cadherin binding
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
cadherin binding involved in cell-cell adhesion
nuclear hormone receptor binding
desmosome assembly
cytoskeletal anchoring at plasma membrane
signal transduction
single organismal cell-cell adhesion
cell migration
adherens junction organization
adherens junction assembly
regulation of cell proliferation
positive regulation of protein import into nucleus
skin development
detection of mechanical stimulus
positive regulation of sequence-specific DNA binding transcription factor activity
protein heterooligomerization
endothelial cell-cell adhesion
cellular response to indole-3-methanol
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
positive regulation of canonical Wnt signaling pathway
regulation of ventricular cardiac muscle cell action potential
cell adhesion
regulation of cell fate specification
positive regulation of transcription from RNA polymerase II promoter
ventricular cardiac muscle cell action potential
bundle of His cell to Purkinje myocyte communication
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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