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gamma catenin Polyclonal Antibody

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Questions & Answers

Questions & Answers

Antibody Testing Data (12)

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 12

gamma catenin Antibody (11146-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human pancreas cancer using 11146-1-AP (Plakoglobin/gamma catenin antibody) at dilution of 1:50 (under 10x lens).

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

gamma catenin Antibody in Western Blot (WB)

gamma catenin Antibody in Western Blot (WB)

gamma catenin Antibody in Western Blot (WB)

gamma catenin Antibody in Western Blot (WB)

gamma catenin Antibody in Western Blot (WB)

Product Image Gallery

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human pancreas cancer using 11146-1-AP (Plakoglobin/gamma catenin antibody) at dilution of 1:50 (under 10x lens).

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer slide using 11146-1-AP (Plakoglobin/gamma catenin antibody at dilution of 1:50.

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer slide using 11146-1-AP (Plakoglobin/gamma catenin antibody at dilution of 1:50.

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer slide using 11146-1-AP (Plakoglobin/gamma catenin antibody at dilution of 1:50.

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer slide using 11146-1-AP (Plakoglobin/gamma catenin antibody at dilution of 1:50.

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human skin slide using 11146-1-AP (Plakoglobin/gamma catenin antibody at dilution of 1:50.

gamma catenin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human skin slide using 11146-1-AP (Plakoglobin/gamma catenin antibody at dilution of 1:50.

gamma catenin Antibody in Western Blot (WB) — Mouse heart tissue were subjected to SDS PAGE followed by western blot with 11146-1-AP ( Plakoglobin/gamma catenin antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

gamma catenin Antibody in Western Blot (WB) — Human heart tissue were subjected to SDS PAGE followed by western blot with 11146-1-AP (Plakoglobin/gamma catenin antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours.

gamma catenin Antibody in Western Blot (WB) — T-47D cells were subjected to SDS PAGE followed by western blot with 11146-1-AP (Plakoglobin/gamma catenin antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

gamma catenin Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 11146-1-AP (Plakoglobin/gamma catenin antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

gamma catenin Antibody in Western Blot (WB) — A431 cells were subjected to SDS PAGE followed by western blot with 11146-1-AP (Plakoglobin/gamma catenin antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

Product Details

11146-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

-

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

gamma catenin Fusion Protein Ag1627 (396-745 aa encoded by BC011865)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LVNQLSVDD VNVLTCATGT LSNLTCNNSK NKTLVTQNSG VEALIHAILR AGDKDDITEP AVCALRHLTS RHPEAEMAQN SVRLNYGIPA IVKLLNQPNQ WPLVKATIGL IRNLALCPAN HAPLQEAAVI PRLVQLLVKA HQDAQRHVAA GTQQPYTDGV RMEEIVEGCT GALHILARDP MNRMEIFRLN TIPLFVQLLY SSVENIQRVA AGVLCELAQD KEAADAIDAE GASAPLMELL HSRNEGTATY AAAVLFRISE DKNPDYRKRV SVELTNSLFK HDPAAWEAAQ SMIPINEPYG DDLDATYRPM YSSDVPLDPL EMHMDMDGDY PIDTYSDGLR PPYPTADHML A (396-745 aa encoded by BC011865)

Target Information

JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.

Cell reports

Xie W,Gao S,Yang Y,Li H,Zhou J,Chen M,Yang S,Zhang Y,Zhang L,Meng X,Xie S,Liu M,Li D,Chen Y,Zhou J

Tue Dec 27 00:00:00 EST 2022

CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.

Cell reports

Xie W,Gao S,Yang Y,Li H,Zhou J,Chen M,Yang S,Zhang Y,Zhang L,Meng X,Xie S,Liu M,Li D,Chen Y,Zhou J

Tue Dec 27 00:00:00 EST 2022

CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.

Cell reports

Xie W,Gao S,Yang Y,Li H,Zhou J,Chen M,Yang S,Zhang Y,Zhang L,Meng X,Xie S,Liu M,Li D,Chen Y,Zhou J

Tue Dec 27 00:00:00 EST 2022

CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.

Cell reports

Xie W,Gao S,Yang Y,Li H,Zhou J,Chen M,Yang S,Zhang Y,Zhang L,Meng X,Xie S,Liu M,Li D,Chen Y,Zhou J

Tue Dec 27 00:00:00 EST 2022

CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.

Cell reports

Xie W,Gao S,Yang Y,Li H,Zhou J,Chen M,Yang S,Zhang Y,Zhang L,Meng X,Xie S,Liu M,Li D,Chen Y,Zhou J

Tue Dec 27 00:00:00 EST 2022

Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.

Biochemical and biophysical research communications

Fang Y,Li F,Qi C,Mao X,Xu Y,Zhao Z,Wu H,Zhang Z

Thu Aug 13 00:00:00 EDT 2020

The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.

The Journal of clinical investigation

Li W,Zhang Z,Liu X,Cheng X,Zhang Y,Han X,Zhang Y,Liu S,Yang J,Xu B,He L,Sun L,Liang J,Shang Y

Fri Sep 01 00:00:00 EDT 2017

The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.

The Journal of clinical investigation

Li W,Zhang Z,Liu X,Cheng X,Zhang Y,Han X,Zhang Y,Liu S,Yang J,Xu B,He L,Sun L,Liang J,Shang Y

Fri Sep 01 00:00:00 EDT 2017

Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.

PloS one

Sun B,Bai Y,Zhang L,Gong L,Qi X,Li H,Wang F,Chi X,Jiang Y,Shao S

Wed Nov 20 00:00:00 EST 2019

Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.

PloS one

Sun B,Bai Y,Zhang L,Gong L,Qi X,Li H,Wang F,Chi X,Jiang Y,Shao S

Wed Nov 20 00:00:00 EST 2019

Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis.

Oncogene

Shriver M,Stroka KM,Vitolo MI,Martin S,Huso DL,Konstantopoulos K,Kontrogianni-Konstantopoulos A

Thu Aug 06 00:00:00 EDT 2015

Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis.

Oncogene

Shriver M,Stroka KM,Vitolo MI,Martin S,Huso DL,Konstantopoulos K,Kontrogianni-Konstantopoulos A

Thu Aug 06 00:00:00 EDT 2015

Bioinformatics

Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; OTTHUMP00000164735

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Gene Aliases: ARVD12; CTNNG; D930025P04Rik; DP3; DPIII; JUP; PDGB; PG; PKGB

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UniProt ID: (Human) P14923, (Rat) Q6P0K8, (Mouse) Q02257

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Entrez Gene ID: (Human) 3728, (Rat) 81679, (Mouse) 16480

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transcription coactivator activity signal transducer activity structural molecule activity structural constituent of cell wall protein binding protein kinase binding protein phosphatase binding protein homodimerization activity alpha-catenin binding cadherin binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication cadherin binding involved in cell-cell adhesion nuclear hormone receptor binding

Process(es)

desmosome assembly cytoskeletal anchoring at plasma membrane signal transduction single organismal cell-cell adhesion cell migration adherens junction organization adherens junction assembly regulation of cell proliferation positive regulation of protein import into nucleus skin development detection of mechanical stimulus positive regulation of sequence-specific DNA binding transcription factor activity protein heterooligomerization endothelial cell-cell adhesion cellular response to indole-3-methanol bundle of His cell-Purkinje myocyte adhesion involved in cell communication regulation of heart rate by cardiac conduction establishment of protein localization to plasma membrane positive regulation of canonical Wnt signaling pathway regulation of ventricular cardiac muscle cell action potential cell adhesion regulation of cell fate specification positive regulation of transcription from RNA polymerase II promoter ventricular cardiac muscle cell action potential bundle of His cell to Purkinje myocyte communication regulation of nucleic acid-templated transcription

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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