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Antibody detects endogenous levels of total hnRNP C1/C2.
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.
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Protein Aliases: heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); heterogeneous nuclear ribonucleoprotein C1; heterogeneous nuclear ribonucleoprotein C2; Heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous ribonucleoprotein C1/C2; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1 / hnRNP C2; hnRNP C1/C2; hnRNP C2; hnRNP core protein C; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; snoRNA MBI-122
Gene Aliases: AL022939; C1; C2; D14Wsu171e; HNRNP; hnRNP C; hnrnp-C; HNRNPC; hnRNPC1; hnRNPC2; HNRPC; Hnrpc1; Hnrpc2; SNRPC
UniProt ID: (Human) P07910, (Mouse) Q9Z204
Entrez Gene ID: (Human) 3183, (Rat) 290046, (Mouse) 15381
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