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human IgG heavy chain Polyclonal Antibody

human IgG heavy chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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human IgG heavy chain Antibody (16402-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using (Product # 16402-1-AP) (human IgG heavy chain antibody) at dilution of 1:200 (under 4x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

human IgG heavy chain Antibody in Western Blot (WB)

Product Image Gallery

Product Details

16402-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:20,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

View 3 publications 3 publications

RNA Immunoprecipitation (RIP)

View 2 publications 2 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

human IgG heavy chain Fusion Protein Ag9519 (124-473 aa encoded by BC025985)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody detects all the Heavy chain of human immunoglobulin gamma (IgG), IgG1, IgG2, IgG3, IgG4 included.

Immunogen sequence: AAGHLVMGF GAHWGQGKLV SVSPASTKGP SVFPLAPCSR STSESTAALG CLVKDYFPEP VTVSWNSGAL TSGVHTFPAV LQSSGLYSLS SVVTVPSSSL GTKTYTCNVD HKPSNTKVDK RVESKYGPPC PSCPAPEFLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SQEDPEVQFN WYVDGVEVHN AKTKPREEQF NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK GLPSSIEKTI SKAKGQPREP QVYTLPPSQE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSRLTVDKSR WQEGNVFSCS VMHEALHNHY TQKSLSLSLG K (124-473 aa encoded by BC025985)

Target Information

Antibodies are comprised of heavy and light chains. A state of disease can occur if the heavy chain of IgG is overproduced. Diseases associated with gamma heavy chain over production mainly affects older adults and has similarity to malignant lymphoma. On the other hand, some individuals that are affected by gamma heavy chain over production may be asymptomatic.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Tue May 30 00:00:00 EDT 2023

Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.

Journal of physiology and biochemistry

Ding R,Li G,Yao Y,Zhang L,Zhang X,Li J,Shen T,Gao Y,Wu T,Kong S,Huang M,Li Y

Tue Feb 01 00:00:00 EST 2022

A Circ-0007022/miR-338-3p/Neuropilin-1 Axis Reduces the Radiosensitivity of Esophageal Squamous Cell Carcinoma by Activating Epithelial-To-Mesenchymal Transition and PI3K/AKT Pathway.

Frontiers in genetics

Zhang J,Yu Y,Yin X,Feng L,Li Z,Liu X,Yu X,Li B

Sat Jul 16 00:00:00 EDT 2022

Pathologic light chain amyloidosis oligomer detection in urinary extracellular vesicles as a diagnostic tool for response and progression of disease.

Frontiers in oncology

Cooper SA,Dick CJ,Misra P,Leung N,Schinstock CA,Ramirez-Alvarado M

Sat Oct 22 00:00:00 EDT 2022

Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia-inducible factor-1α in colorectal cancer.

Molecular oncology

Fang C,Dai L,Wang C,Fan C,Yu Y,Yang L,Deng H,Zhou Z

Wed Dec 01 00:00:00 EST 2021

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia.

Nature communications

Llorens F,Hermann P,Villar-Piqué A,Diaz-Lucena D,Nägga K,Hansson O,Santana I,Schmitz M,Schmidt C,Varges D,Goebel S,Dumurgier J,Zetterberg H,Blennow K,Paquet C,Baldeiras I,Ferrer I,Zerr I

Thu Jan 30 00:00:00 EST 2020

Oridonin induces apoptosis in HGC-27 cells by activating the JNK signaling pathway.

Oncology letters

Ren DL,Ghoorun RA,Wu XH,Chen HL,Zhou Q,Wu XB

Wed Jan 01 00:00:00 EST 2020

Plasma total prion protein as a potential biomarker for neurodegenerative dementia: diagnostic accuracy in the spectrum of prion diseases.

Neuropathology and applied neurobiology

Llorens F,Villar-Piqué A,Schmitz M,Diaz-Lucena D,Wohlhage M,Hermann P,Goebel S,Schmidt I,Glatzel M,Hauw JJ,Sikorska B,Liberski PP,Riggert J,Ferrer I,Zerr I

Wed Apr 01 00:00:00 EDT 2020

Upregulation of IGF1 by tumor-associated macrophages promotes the proliferation and migration of epithelial ovarian cancer cells.

Oncology reports

Liu L,Wang X,Li X,Wu X,Tang M,Wang X

Thu Feb 01 00:00:00 EST 2018

PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.

Experimental and therapeutic medicine

Xu X,Cui Y,Cao L,Zhang Y,Yin Y,Hu X

Mon May 01 00:00:00 EDT 2017

PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.

Experimental and therapeutic medicine

Xu X,Cui Y,Cao L,Zhang Y,Yin Y,Hu X

Mon May 01 00:00:00 EDT 2017

Identification of Potential Biomarkers for Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment by Vitreous iTRAQ-Based Proteomic Profiling.

International journal of molecular sciences

Wu Z,Ding N,Yu M,Wang K,Luo S,Zou W,Zhou Y,Yan B,Jiang Q

Wed Dec 07 00:00:00 EST 2016

Identification of Potential Biomarkers for Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment by Vitreous iTRAQ-Based Proteomic Profiling.

International journal of molecular sciences

Wu Z,Ding N,Yu M,Wang K,Luo S,Zou W,Zhou Y,Yan B,Jiang Q

Wed Dec 07 00:00:00 EST 2016

Bioinformatics

Protein Aliases: Immunoglobulin G; ImmunoglobulinG

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Entrez Gene ID: (Human) 3503

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Function(s)

immunoglobulin

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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human IgG heavy chain Polyclonal Antibody

human IgG heavy chain Antibody (16402-1-AP) in IHC (P)

Product Details

16402-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

RNA Immunoprecipitation (RIP)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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