Alomone Labs, LTD

mu-Opioid Receptor (OPRM1) (extracellular) Polyclonal Antibody, Atto™ 488

View all (31) OPRM1 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

AOR-011-AG-50UL

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

10-15 µg/5x10^5 cells
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CSPAPGSWLNLSHVDGN, corresponding to amino acid residues 22-38 of rat mu-Opioid receptor, Extracellular, N-terminus
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Conjugate

Atto™ 488 Atto™ 488 Atto™ 488

Excitation/Emission Max

501/523 nm

Form

Lyophilized

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Information

The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: hMOP; KIAA0403; M-OR-1; MOP; MOP receptor; MOR-1; MOR-1C; Mu opiate receptor; Mu opioid receptor; mu opioid receptor hMOR-1a; mu opioid receptor splice variant mMOR-1Z; mu opioid receptor splice variant rMOR-1S; mu opioid receptor splice variant rMOR-1Z; Mu-type opioid receptor; MUOR1; Opioid mu receptor; Opioid Receptor; Opioid receptor B; opioid receptor, mu 1; OTTHUMP00000017463

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Gene Aliases: LMOR; M-OR-1; MOP; MOP-R; MOR; MOR-1; MOR-1O; MOR1; MORA; muOR; OPRM; OPRM1; Oprrm1; Ror-b

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UniProt ID: (Human) P35372, (Rat) Q64120, (Mouse) P42866

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Entrez Gene ID: (Human) 4988, (Rat) 25601, (Mouse) 18390

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Function(s)
G-protein alpha-subunit binding G-protein coupled receptor activity beta-endorphin receptor activity voltage-gated calcium channel activity protein binding protein C-terminus binding protein domain specific binding filamin binding G-protein beta-subunit binding morphine receptor activity neuropeptide binding opioid receptor activity signal transducer activity G-protein coupled receptor transmembrane signal receptor
Process(es)
acute inflammatory response to antigenic stimulus G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-activating dopamine receptor signaling pathway negative regulation of adenylate cyclase activity phospholipase C-activating G-protein coupled receptor signaling pathway neuropeptide signaling pathway chemical synaptic transmission sensory perception locomotory behavior negative regulation of cell proliferation response to radiation sensory perception of pain adenylate cyclase-inhibiting opioid receptor signaling pathway response to food positive regulation of appetite response to lipopolysaccharide cellular response to stress wound healing response to cocaine eating behavior estrous cycle behavioral response to ethanol positive regulation of neurogenesis regulation of sensory perception of pain excitatory postsynaptic potential negative regulation of Wnt protein secretion positive regulation of ERK1 and ERK2 cascade calcium ion transmembrane transport response to growth factor cellular response to morphine regulation of N-methyl-D-aspartate selective glutamate receptor activity immune response G-protein coupled receptor signaling pathway adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration opioid receptor signaling pathway response to morphine positive regulation of cAMP-mediated signaling negative regulation of cAMP-mediated signaling negative regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process response to ethanol negative regulation of cytosolic calcium ion concentration signal transduction negative regulation of cAMP biosynthetic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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