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p115, USO1 Antibody (68100-1-IG150UL) in IHC (P)
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using (Product # 68100-1-IG150UL) (p115, USO1 antibody) at dilution of 1:1,000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Product Details
68100-1-IG150UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3B7D8
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: General vesicular transport factor p115; Protein USO1 homolog; TAP; transcytosis associated protein; transcytosis associated protein p115; Transcytosis-associated protein; USO1 homolog, vesicle docking protein; USO1 vesicle docking protein homolog; VDP p115; vesicle docking protein p115; vesicle docking protein, 115 kDa; Vesicle-docking protein
Gene Aliases: 115kDa; P115; TAP; USO1; VDP
UniProt ID: (Human) O60763, (Mouse) Q9Z1Z0, (Rat) P41542
Entrez Gene ID: (Human) 8615, (Mouse) 56041, (Rat) 56042
intracellular protein transport
ER to Golgi vesicle-mediated transport
transcytosis
COPII vesicle coating
Golgi vesicle docking
vesicle fusion with Golgi apparatus
membrane fusion
cell-cell adhesion
transport
protein transport
vesicle-mediated transport
Golgi vesicle transport
intra-Golgi vesicle-mediated transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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