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Invitrogen
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Store as concentrated solution.
Centrifuge briefly prior to opening vial.
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains|The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism|Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome|Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms|Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BCC7; BMFS5; LFS1; P53; TRP53; tumor protein p53
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